Clinical trials: Healthy Adult Volunteers
Healthy
Bioequivalence Study of Gabapentin 400 mg Capsules Under Fed Conditions
To compare the single-dose oral bioavailability of metformin HCI liquid 500 mg/5 mL of Ranbaxy with Glucophage® 1000 mg tablets of Bristol-Myers, USA following administration of a 1000 mg dose in healthy, adult, male and female…
- Trial name
- NCT00778765
- Testing
- 400 mg Gabapentin Capsules
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Healthy
GRC 27864 First in Man, Single Ascending Dose Study in Healthy Volunteers
A Single Dose Study of GRC 27864 in Healthy Volunteers.
- Trial name
- NCT02179645
- Testing
- GRC 27864, Celecoxib
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Gastritis
Clinical Trial to Evaluate the Safety and Pharmacokinetic/Pharmacodynamic Characteristics of DW1903
A Randomized, Open-label, Oral in healthy male volunteers
- Trial name
- NCT05155072
- Testing
- DW1903, DW1903-R1, DW1903-R2
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Healthy
A Multiple-Dose Study to Assess the Safety, Tolerability, and Steady State Pharmacokinetics of APD791 in Healthy Volunteers
The APD791-002 study is designed primarily to evaluate the safety, tolerability, and pharmacokinetics of APD791 when administered for 7 days to healthy adult subjects.
- Trial name
- NCT00619931
- Testing
- APD791
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Arena Pharmaceuticals
Type2 Diabetes Mellitus
A Clinical Trial to Investigate the Pharmacokinetics and Safety/Tolerability of CKD-386 in Healthy Adult Volunteers
The purpose of this study is to evaluate the pharmacokinetics and Safety/Tolerability of CKD-386
- Trial name
- NCT04223895
- Testing
- CKD-386 Formulation 1, CKD-386 Formulation 2, D012, D326 and D337
- Volunteers
- 30 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Healthy
A Phase 1 Study of BLKR201 in Healthy Adult Participants
The goal of this clinical trial is to learn if BLKR201 is safe in healthy adults. Researchers will also learn how the body absorbs and processes BLKR201 and how food may affect it.
- Trial name
- NCT07501039
- Testing
- BLKR201
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Formation Bio, Inc.
Healthy
A Study to Learn How Different Amounts of the Study Medicine Called PF-07940369 Are Tolerated and Act in the Body in Healthy Adults.
The purpose of the study is to evaluate the safety, tolerability, and Pharmacokinetics (Pharmacokinetics [PK] to better understand how the drug is changed and eliminated from your body after you take it) of single ascending oral…
- Trial name
- NCT06532383
- Testing
- PF-07940369
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Adult Participants
A Phase 1 Study of KHN707 Tablets in Healthy Participants
This is a single-center, randomized, double-blind, placebo-controlled study . The objective is to evaluate the safety , tolerability and PK profile of KHN707 tablets in Chinese healthy participants.
- Trial name
- NCT07557537
- Testing
- KHN707 tablet
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Chengdu Kanghong Pharmaceutical Group Co., Ltd.
Healthy Volunteers
Study to Evaluate Bioavailability of Apremilast Oral Suspension Relative to Tablet and to Assess Effect of Food on the Pharmacokinetics (PK) of the Oral Suspension
The purpose of this study is to assess how much of apremilast is found in the blood unchanged when administered as an oral suspension compared to when it is administered as a tablet formulation.
- Trial name
- NCT02641353
- Testing
- Apremilast Tablet, Apremilast Oral Suspension
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Amgen
Decompression Sickness
NASA Exercise Prebreathe Study
This study evaluates oxygen prebreathe protocols and exercise conditions to reduce risk of decompression sickness during simulated extravehicular activity.
- Trial name
- NCT07702539
- Testing
- Oxygen Prebreathe and Hypobaric Exposure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duke University
Meningococcal Immunisation, Healthy Volunteers
Study of an Investigational Pentavalent Meningococcal ABCYW Vaccine in Adults and Adolescents
The purpose of VAN00010 study is to assess the safety and immunogenicity of the investigational pentavalent meningococcal ABCYW vaccine in adults and adolescents. The study duration will be up to 12 months for all participants.
- Trial name
- NCT06128733
- Testing
- Pentavalent Meningococcal ABCYW vaccine, MenACYW conjugate vaccine, Meningococcal group B vaccine
- Where
- 47 sites in United States, Puerto Rico
- Volunteers
- 1,215 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Healthy
Effect of Gamma Tocopherol Supplementation on Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Normal Adults
The purpose of this research study is to learn whether high dose vitamin E (gamma tocopherol) will affect the way your body responds to an acute inflammation in your lungs.
- Trial name
- GammaTox (NCT00631085)
- Testing
- gamma tocopherol
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy, Adults
Cerebral Oxygenation Values in Healthy Adults Volunteers Measured With RheoPatch and NIRO-200NX
Noninvasive measurement of cerebral tissue oxygen saturation levels by near infrared spectroscopy (NIRS) is clinical routine in perioperative medicine.
- Trial name
- NCT05460585
- Testing
- Cerebral oximetry using Rheopatch, Cerebral oximetry using NIRO-200NX
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy Adult Females
Pharmacokinetics of Tenofovir, Emtricitabine, Maraviroc, and Raltegravir in Cervical, Vaginal, and Rectal Tissues and Secretions
The purpose of this study is to develop a predictive antiretroviral pharmacokinetic model of mucosal fluid and tissue distribution in genital tract fluid, rectal fluid and 3 mucosal tissues.
- Trial name
- NCT01330199
- Testing
- Pharmacokinetic Sampling
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
A Study to Compare Different Preparations of Sisunatovir in Healthy Adult Participants.
The purpose of this study is to learn how different preparations of sisunatovir are taken up into the blood when taken on an empty stomach or with a meal in healthy adults.
- Trial name
- NCT05994963
- Testing
- sisunatovir
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteers
A Study to Compare Two Bioanalytical Assays for Tebipenem
The primary purpose of the study is to compare the concentrations of tebipenem (TBP), the active moiety of tebipenem pivoxil hydrobromide (TBP-PI-HBr), as determined by two bioanalytical assays, a whole blood assay and a plasma…
- Trial name
- NCT05856747
- Testing
- TBP-PI-HBr
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Spero Therapeutics
Human Brain and Cognition
Investigating the Plasticity of Human Predictive Coding Through Neuromodulation
The hypothesis of the study is to investigate how different trm (tES) methods (transcranial Alternating Current Stimulation, tACS, and transcranial Random Noise Stimulation, tRNS) applied at different stimulation frequencies and…
- Trial name
- PREDICOM (NCT06374433)
- Testing
- Occipital tACS at IAF-2Hz, Occipital tACS at IAF+2Hz, Frontal tACS at 4-7 Hz
- Where
- Italy
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Human Volunteers
A Study To Estimate The Effect Of Ketoconazole On The Pharmacokinetics Of Pf-04937319 In Healthy Subjects
This study will evaluate the potential for a drug-drug interaction of PF-04937319 with ketoconazole, a potent inhibitor of the drug metabolizing enzyme CYP3A.
- Trial name
- NCT01468714
- Testing
- PF-04937319 / ketoconazole
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Subjects
VNRX-5024 Safety and PK in Healthy Adult Volunteers
This is a 2-part dose-ranging study to evaluate the safety and pharmacokinetics of escalating doses of VNRX-5024. Subjects will be enrolled in one of three dose cohorts.
- Trial name
- NCT04314206
- Testing
- VNRX-5024
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Basilea Pharmaceutica
Healthy Volunteers
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Mitapivat (AG-348) in Healthy Adult Participants
This is a Phase 1, randomized, single-dose, double-blinded, 4-period, crossover study to evaluate the pharmacokinetics, safety, and tolerability of mitapivat in healthy adult participants under fasted and fed (high-fat meal)…
- Trial name
- NCT04472832
- Testing
- Mitapivat 100 mg, Mitapivat 300 mg
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Agios Pharmaceuticals, Inc.
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