Clinical trials: Healthy Adult Volunteers
Adult Healthy Volunteers
Open Label Phase 1 Pharmacokinetics and Tolerability Study of Single TAB08 Administration in Healthy Volunteers
The purpose of this study is to assess safety and tolerability of ascending dosed of TAB08 after single i.v. infusion to the adult healthy volunteers.
- Trial name
- NCT01885624
- Testing
- TAB08
- Where
- Russia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Theramab LLC
Healthy Volunteers in Fed and Fasted State
Pharmacokinetics of Zelquistinel in Fasted or Fed State
The primary purpose of this study is to assess the effect of food on the rate and extent of absorption of a single dose of Zelquistinel 3 mg or 10 mg oral tablets tablets in healthy adult volunteers.
- Trial name
- GATE-251 (NCT07099989)
- Testing
- Zelquistinel 3 mg, Zelquistinel 10 mg
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Syndeio Biosciences, Inc
Pharmacodynamic Response to Small Doses of Insulin
Transdermal Insulin Response In Healthy Volunteers
Bio-fermentation produced Human insulin is available without prescription in the U.S. This study is a physician-initiated trial of a formula enabling transdermal delivery of human insulin.
- Trial name
- NCT04857320
- Testing
- Human insulin
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Transdermal Delivery Solutions Corp
Healthy
Pharmacokinetic Study Of Ibuprofen Injection (IVIb) In Healthy Adult Subjects
The primary objective of this study is to evaluate the pharmacokinetic profile of a single dose of IVIb administered over 5-7 minutes.
- Trial name
- NCT00867880
- Testing
- IVIb
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Healthy Volunteers
Phase 1 Study of IPG1094 Safety, Tolerability, and PK in Healthy Participants
This is a phase 1, first-in-human, randomized, double-blind, placebo-controlled, single dose escalation study to evaluate the safety, tolerability, and PK of single dose orally administered IPG1094 in healthy adult participants.
- Trial name
- NCT05112159
- Testing
- IPG1094 300 mg SAD, IPG1094 600 mg SAD, IPG1094 900 mg SAD
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Nanjing Immunophage Biotech Co., Ltd
Healthy Volunteers
A Study of the Safety, Tolerability, and Bioavailability of Orally Administered Venglustat in Healthy Adult Participants
The purpose of this study is to assess the effect of food on the bioavailability of venglustat and to assess the relative bioavailability of venglustat tablet swallowed whole with water versus a tablet chewed and then swallowed…
- Trial name
- NCT06418620
- Testing
- Venglustat
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Sanofi
Respiratory Syncytial Virus Infection, Healthy Volunteers
Study of a Respiratory Syncytial Virus Candidate Formulation in Adults Aged 60 Years and Older
The purpose of this Phase IIb study is to evaluate the efficacy of the RSV vaccine candidate for the prevention of lower respiratory tract disease (LRTD) due to RSV.
- Trial name
- NCT06251024
- Testing
- RSV vaccine candidate
- Where
- 25 sites in Australia, Chile and 4 more
- Volunteers
- 4,541 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Lower Extremity Arterial Occlusive Diseases
The Safety and Tolerability of Alprostadil Liposome for Injection in Healthy Adult Volunteers
Conducted in Chinese healthy adult volunteers,the study aims to observe the safety, tolerability and pharmacokinetic of single-dose administration of different doses of Alprostadil Liposome for Injection as well as to confirm the…
- Trial name
- NCT03669562
- Testing
- Alprostadil Liposome for Injection
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Healthy Volunteer
Comparative Bioavailability Study of Tablet and Granule Formulations of ADC189 and the Study of Ultra-high Dose
Part 1 of this study will compare the pharmacokinetic performance of tablet and granule formulations of ADC189 under fasted conditions in healthy volunteers. A randomized, two-period, two-treatment crossover design is used.
- Trial name
- NCT06428903
- Testing
- ADC189 tablet, ADC189 granules, ADC189 180mg
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Jiaxing AnDiCon Biotech Co.,Ltd
Hypertension
A Clinical Trial to Evaluate the Safety and Pharmacokinetics of AJU-C52H in Healthy Volunteers
To evaluate the safety and pharmacokinetic characteristics of AJU-C52H in healthy adults
- Trial name
- NCT05077462
- Testing
- C52R1M Tab. and C52R2 Tab., AJU-C52H
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Healthy
Evaluation of Pharmacokinetic/Pharmacodynamic Properties and Safety of Leucostim® Compared to Neupogen® in Healthy Adult Volunteers
A Randomized, Open-label, Two-way Crossover, Open-label Clinical Trial to Compare Pharmacokinetic/Pharmacodynamic Properties and Safety after Subcutaneous Administration of Leucostim® and Neupogen® in Healthy Adult Volunteers
- Trial name
- NCT02725086
- Testing
- Leucostim®, Neupogen®
- Where
- South Korea
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Healthy Volunteer
A Study of Drug-Drug Interaction Between Danoprevir Coadministered With Low-Dose Ritonavir and Tenofovir Disoproxil Fumarate or Atazanavir
This randomized, open-label, multiple-treatment multiple-dose, 2-period, 2-sequence study will evaluate potential drug-drug interactions between danoprevir (DNV) when coadministered with low-dose ritonavir (r) and tenofovir…
- Trial name
- NCT01592305
- Testing
- atazanavir, danoprevir, ritonavir
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Allergic Contact Dermatitis
Evaluation of EB01 Cream for the Treatment of Chronic Allergic Contact Dermatitis
The purpose of this study is to evaluate the safety and efficacy of EB01 Cream (0.2%, 1.0%, 2.0%) applied twice per day (BID) for the treatment of moderate to severe chronic allergic contact dermatitis (ACD).
- Trial name
- NCT03680131
- Testing
- EB01 Cream 0.2%, EB01 Cream 1.0%, EB01 Cream 2.0%
- Where
- 15 sites in United States, Canada
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Edesa Biotech Inc.
Healthy Adults
Safety of an Oral Probiotic in Healthy Adults
The purpose of this study is to evaluate the safety of an oral probiotic in healthy individuals.
- Trial name
- NCT04492631
- Testing
- Streptococcus salivarius DB-B5
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Dose Biosystems Inc.
Chronic Hepatitis b
Bioequivalence Study of Entecavir Tablets and Baraclude® Under Fasting Condition in Chinese Healthy Volunteers
A single-center, open-Label, randomized, single-dose, two-period, two-sequence, crossover study to assess the bioequivalence of test formulation entecavir tablets 1.0 mg with reference formulation entecavir tablets (Baraclude®)…
- Trial name
- NCT03847246
- Testing
- Baraclude® tablets,1.0 mg, Entecavir tablets,1.0 mg
- Where
- China
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Healthy Volunteers
Comparative Immunogenicity Study Comparing TPI-120 to Neulasta® in Healthy Adult Subjects
This study will compare treatment emergent incidence rate of ADA between TPI-120 and US licensed Neulasta in normal healthy adult subjects
- Trial name
- TPI-120 (NCT03202927)
- Testing
- PEGFILGRASTIM
- Where
- 2 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Adello Biologics, LLC
Healthy Volunteers
A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants
The Purpose of this study is to assess the relative bioavailability, dose proportionality, the impact of food on the rate and extent of absorption, palatability of the selected pediatric formulation of maribavir and the safety…
- Trial name
- NCT04131556
- Testing
- Maribavir
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shire
Healthy Volunteers
Evaluation of Oral PF614 Relative to OxyContin (PF614-102)
This is a single-center study incorporating 2 parts: A Multiple Ascending Dose Study (Part A) and a comparative Bioavailability/Bioequivalence and Food Effect study (Part B).
- Trial name
- NCT05043766
- Testing
- PF614, Naltrexone Hydrochloride, OxyContin
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ensysce Biosciences
Healthy Volunteers (HV)
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of KR25102 in Healthy Volunteers
Phase 1 Single Ascending Doses(SAD): Six cohorts of 53 healthy volunteers (HVs) will receive a single IV bolus injection of study drug or placebo.
- Trial name
- NCT07618156
- Testing
- KR25102 for Injection
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Jiangxi Kvvit Pharmaceutical Co., Ltd.
Healthy Adult Volunteer
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetics of DW4421-T1 and DW4421S-T1 in Healthy Adult Volunteers
Safety and pharmacokinetic characteristics evaluation of DW4421-T1 and DW4421S-T1
- Trial name
- NCT07364851
- Testing
- DW4421-T1, DW4421S-T1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.