Clinical trials: Healthy Adult Volunteers
Atopic Dermatitis
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)
This is a Phase 1, randomized, blinded, placebo controlled, single-ascending dose (SAD) and multiple-ascending dose (MAD) study of BBT001 in healthy volunteers (HVs) and adult patients with moderate to severe Atopic Dermatitis…
- Trial name
- NCT06808477
- Testing
- BBT001
- Where
- 14 sites in United States, Australia and 2 more
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Bambusa Therapeutics
Healthy Volunteers
Study to Assess Adverse Events and Compare How Oral Ubrogepant and Oral Atogepant Moves Through the Body of Healthy Female Adult Volunteers
This study will assess adverse events and compare how ubrogepant and atogepant tablets move through the body of healthy adult lactating female participants.
- Trial name
- NCT05892757
- Testing
- Atogepant, Ubrogepant
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- AbbVie
Healthy, Immunisation Against Streptococcus Pneumoniae
Phase I Study With V-212 Vaccinations in Healthy Adult Volunteers
Virometix AG, is conducting research into a vaccine (V-212) to prevent pneumococcal disease, which is any type of illness caused by infection with a bacterium called Streptococcus pneumoniae (S. pneumoniae).
- Trial name
- NCT06975319
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Virometix
Group B Streptococcal Infections
Phase I/II Study to a Assess the GBS-06 Vaccine Manufactured by Inventprise, Inc., in Healthy, Non-Pregnant, Adult Women of Childbearing Age.
To assess the safety and tolerability of IVT GBS-06 vaccine administered as a single-dose regimen, at three dosage levels in healthy, non-pregnant, adult women of childbearing age (WOCBA).
- Trial name
- NCT06611371
- Testing
- IVT GBS-06
- Where
- 2 sites in United States, South Africa
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Inventprise Inc.
Healthy Volunteers
A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.
The objective of this study is to assess the effect of repeated doses of ABBV-722 on the single dose pharmacokinetics (PK) of Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin
- Trial name
- NCT07567781
- Testing
- ABBV-722, Midazolam, Metformin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AbbVie
Healthy Volunteers
Single-Dose Study of MT203
The purpose of this study is to evaluate safety, pharmacokinetics and pharmacodynamics of single subcutaneous injection of MT203 in healthy adult Japanese and Caucasian male participants.
- Trial name
- NCT02354599
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy
Drug Interaction Study Between Erdosteine and Bepotastine Besilate in Healthy Adult Volunteers
The purpose of this study is to evaluate the drug-drug interaction between Erdosteine and Bepotastine besilate in healthy adult volunteers.
- Trial name
- NCT02332044
- Testing
- Erdos, Talion, Erdos, Talion
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy
To Demonstrate the Relative Bioavailability of Cefzil 250 mg/5 ml Cefprozil Oral Suspension Fed Conditions
To demonstrate the relative bioavailability of Cefzil 250 mg/5 ml oral suspension fed conditions.
- Trial name
- NCT00881400
- Testing
- Cefprozil 250 mg/5 ml Oral Suspension (Sandoz, Austria), Cefzil (Cefprozil) 250 mg/5 ml Oral Suspension (Bristol-Myers Squibb, USA)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sandoz
Healthy Volunteers
A Study to Evaluate Single and Multiple Doses of SEP-631 in Healthy Adult Volunteers
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and food effects of oral SEP-631 in healthy adult volunteers.
- Trial name
- NCT07069036
- Testing
- SEP-631
- Where
- Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Septerna, Inc.
Infection, Human Immunodeficiency Virus
Drug Interaction Study Between Dolutegravir and Prednisone
Dolutegravir (DTG, GSK1349572 is an integrase inhibitor that is currently in Phase 3 clinical development for the treatment of human immunodeficiency virus (HIV) infection.
- Trial name
- NCT01425099
- Testing
- Dolutegravir, Prednisone
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Healthy Volunteers
A Study to Test a Single Dose of a New Tablet Formulation of TRTL-729
This study assesses the safety, tolerability, and pharmacokinetics (PK) of the tablet formulation of TRTL-729 in healthy adults.
- Trial name
- NCT07811063
- Testing
- TRTL-729
- Where
- New Zealand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tortugas Neuroscience, Inc.
Assisted Reproduction
A Study to Evaluate the Mass Balance of [14C]SHR7280 in Healthy Adult Volunteers
Evaluate the Mass Balance of [14C]SHR7280 in Healthy Adult Volunteers.
- Trial name
- NCT06408948
- Testing
- [14C]SHR7280
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Covid19, SARS CoV 2 Infection
Safety and Immunogenicity Study of Recombinant Protein RBD Candidate Vaccine Against SARS-CoV-2 in Adult Healthy Volunteers (COVID-19)
This is a first-in-human, phase I/IIa, randomized, controlled, observer-blinded, dose-escalation, multicentre clinical trial to evaluate safety and immunogenicity of COVID-19 HIPRA vaccine in adult healthy volunteers.
- Trial name
- NCT05007509
- Testing
- COVID-19 vaccine HIPRA 10, COVID-19 vaccine HIPRA 20, COVID-19 vaccine HIPRA 40
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laboratorios Hipra, S.A.
Healthy Volunteers, Healthy
A Phase 1, Randomized, Placebo-and Positive-Controlled Crossover Study to Determine the Effect of Single-Dose GC4419 on QTc Interval in Healthy Volunteers
This is a partially double-blind study in healthy adult subjects, which will be conducted as a placebo- and active-controlled, single-dose, crossover study.
- Trial name
- NCT03164109
- Testing
- GC4419 IV, Oral moxifloxacin
- Where
- Australia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Galera Therapeutics, Inc.
Healthy Volunteers
Phase 1 Study to Evaluate the PK, Safety, Tolerability of BIIB023 in Chinese, Japanese, and Caucasian Healthy Volunteers
Rationale for the Study: Phase 1 pharmacokinetic (PK) data is needed in Chinese and Japanese populations to support future clinical development of BIIB023 in China and Japan.
- Trial name
- NCT01407406
- Testing
- BIIB023 - low dose IV Dose, BIIB023 - high dose IV Dose
- Where
- 2 sites in Australia, China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biogen
The Focus of the Study is Healthy Volunteers
Appetite Regulation by a Breakfast Soft Bread
The aim of this study is to evaluate the appetite rating of a soft bread with a high content of fibre and protein (Puravita Breakfast®) as well as its capacity to modulate postprandial levels of glucose, insulin and…
- Trial name
- NCT02090049
- Testing
- Puravita Breakfast, Control
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Puratos
Healthy Participants
A Study to Evaluate the Safety, Tolerability and Immunogenicity of Ad35.RSV.FA2 Regimens Boosted With Ad26.RSV.FA2 in Healthy Adult Participants
The purpose of this study is to assess the safety and tolerability of intramuscular homologous and heterologous prime-boost regimens of Ad35.RSV.FA2 (human adenovirus-vectored vaccine candidate) and Ad26.RSV.FA2 in healthy…
- Trial name
- NCT02440035
- Testing
- Ad35.RSV.FA2, Ad26.RSV.FA2
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV
Healthy
A Study To Investigate Safety And Pharmacokinetics Of A Single Dose Of PF-00868554 (Filibuvir) In Japanese Healthy Adult Volunteers
A single dose of PF-00868554 (filibuvir) will be safety and tolerable in Japanese healthy volunteers. The pharmacokinetics in Japanese will be consistent to that available in Western population.
- Trial name
- NCT01051232
- Testing
- Active
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteers
Drug-Drug Interaction Study of Itraconazole, Rifampicin and Midazolam With SIM0417/Ritonavir in Healthy Participants
This is a phase 1, open-label, fixed-sequence, 2-period drug-drug interaction study to evaluate the pharmacokinetic interactions of itraconazole, rifampicin, midazolam, and SIM0417/ritonavir in healthy Chinese subjects.
- Trial name
- NCT05665647
- Testing
- Cohort 1: SIM0417/ritonavir and itraconazole, Cohort 2: SIM0417/ritonavir and rifampicin, Cohort 3: SIM0417/ritonavir and midazolam
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Healthy, Adults
Cerebral Oxygenation Values in Healthy Adults Volunteers Measured With RheoPatch and NIRO-200NX
Noninvasive measurement of cerebral tissue oxygen saturation levels by near infrared spectroscopy (NIRS) is clinical routine in perioperative medicine.
- Trial name
- NCT05460585
- Testing
- Cerebral oximetry using Rheopatch, Cerebral oximetry using NIRO-200NX
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern