Clinical trials: Healthy Adult Volunteers
Tuberculosis
A Leukapheresis Study for Immune Responses in Healthy US Adults Who Receive BCG Vaccination Followed by Boosting With AERAS-402
Healthy adults received BCG on Study Day -84, followed by randomization on Study Day 0 to receive 2 booster doses in a blinded fashion of either AERAS-402 (N=9) or placebo (N=2) on Study Days 0 and 28.
- Trial name
- C-021-402 (NCT02375256)
- Testing
- AERAS-402, BCG (1-8 x105 cfu ID)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Aeras
Healthy Volunteers
Study Comparing TPI-120 and Neulasta Administered Through Subcutaneous Route in Healthy Adult Subjects
This is a single or up to 2 centers, double-blind, randomized, single-dose, two-way, crossover study comparing the Test (T) and Reference (R) products following subcutaneous administration.
- Trial name
- TPI-120 (NCT03206229)
- Testing
- PEG-rhG-CSF, Neulasta (PEG-rhG-CSF)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Adello Biologics, LLC
Healthy Volunteer
A Study to Learn About the Safety of BIIB142 and How it is Processed in the Body of Healthy Adult Participants Aged 18 to 55 Years Old
In this study, researchers will learn more about the safety of BIIB142 and how it is processed in the body. This is the first time that researchers will learn about BIIB142 and how it affects people.
- Trial name
- NCT07133828
- Testing
- BIIB142
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Biogen
Bioequivalence Study
Bioequivalence Study of Spironolactone Tablets in Healthy Subjects
The goal of this clinical trial is to Evaluate the Bioequivalence of Spironolactone Tablets 100mg (by SPH Sine Pharmaceutical Laboratories Co.,Ltd) and ALDACTONE® tablets 100mg (by GD SEARLE LLC) in Chinese Healthy Adult…
- Trial name
- NCT06579053
- Testing
- Spironolactone Tablets (Test), Spironolactone Tablets (Reference)
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- SPH Sine Pharmaceutical Laboratories Co., Ltd.
Anticoagulant
A Clinical Study to Evaluate the Safety and Pharmacokinetics of CKD-344
A Clinical Trial to evaluate the Pharmacokinetics and safety of CKD-344
- Trial name
- NCT04673695
- Testing
- Lixiana(D006), CKD-344
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Healthy Volunteers (HV), Healthy Volunteer
A Study to Assess the Absolute Bioavailability and How Adimanebart SC Moves Through the Body in Healthy Adult Participants
This study aims to find out how much adimanebart gets into the blood circulation of healthy adults. Researchers will measure the amount of adimanebart in blood over time to learn how it moves through the body.
- Trial name
- NCT07673601
- Testing
- Adimanebart IV, Adimanebart SC - formulation A, Adimanebart SC - formulation B
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- argenx
Healthy Adult Participants
Probiotic Research for Mental Health in Adult Volunteers
This randomized, double-blind, placebo-controlled pilot study will evaluate the effects of four weeks of supplementation with a probiotic on mental health in healthy adults aged 18-30 years.
- Trial name
- NCT07751614
- Testing
- Probiotic
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Resistant Hypertension
JX09 SAD/MAD in Healthy Participants
This is a phase 1, randomized, double-blind, placebo-controlled, multi-part, single and multiple ascending dose study in healthy adult to test the safety, tolerability, pharmacokinetics, pharmacodynamics, and food effect of JX09…
- Trial name
- NCT06183671
- Testing
- JX09
- Where
- Australia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Ji Xing Pharmaceuticals Australia Pty Ltd
Healthy Volunteer
A Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of BIIB091, a Bruton's Tyrosine Kinase (BTK) Inhibitor, in Healthy Adult Participants
This study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of BIIB091 in healthy participants.This study will also determine the effect of food on the single oral…
- Trial name
- NCT03943056
- Testing
- BIIB091
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Biogen
Healthy
Pharmacokinetics and Safety Profiles After Administration of DA-5221_01 and Co-administration of 5221_01-R1 and DA-5221_01-R2 in Healthy Adult Volunteers
Pharmacokinetics and Safety Profiles After Administration of DA-5221_01 and Co-administration of 5221_01-R1 and DA-5221_01-R2 in Healthy Adult Volunteers
- Trial name
- NCT06616883
- Testing
- DA-5221_01, DA-5221_01-R1 + DA-5221_01-R2
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Asthma
Single and Multiple Doses of HA115 and Food Effect in Healthy Adult Volunteers
This is a randomized, double-blind, placebo-controlled Phase 1 study of HA115 capsules administered orally to healthy adult volunteers.
- Trial name
- NCT03567694
- Testing
- HA115
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Conjupro Biotherapeutics, Inc.
Wound Heal
Study to Evaluate the Safety of FSR Peptide Versus Placebo Following Punch Biopsy
The purposes of this study is to test the safety of the study drug (FSR peptide) after a punch biopsy in healthy subjects.
- Trial name
- NCT04473859
- Testing
- FSR Peptide 20μM, FSR Peptide 50μM, FSR Peptide 100μM
- Where
- Switzerland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Xequel Bio, Inc.
The Focus of the Study is Healthy Volunteers
Understanding the Effects of Daily Tea Consumption on Attention, Sleep, and Mood, in Healthy Adults
The goal of these series of N-of-1 trials is to compare the effects of three tea interventions on cognition, mood, and sleep, in healthy adult participants.
- Trial name
- Reactivi-Tea (NCT06224569)
- Testing
- Black tea flavoured, tea drink, Black tea flavoured, caffeine-only drink, Green tea flavoured, tea drink
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Healthy
A Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03049423 In Healthy Adult Volunteers And Healthy Older Volunteers
The purpose this study is to evaluate the safety and toleration of PF-03049423 following multiple dose administration as an oral solution to healthy young adult volunteers and healthy elderly volunteers.
- Trial name
- NCT01161069
- Testing
- PF-03049423
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pfizer
Advanced Solid Tumors
Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Healthy Volunteers
This is a double blind Phase I study to evaluate the safety, tolerability, and pharmacokinetics of escalating oral doses of DN1406131, an investigational agent intended to inhibit the indoleamine 2,3-dioxygenase 1 (IDO1) enzyme…
- Trial name
- NCT03641794
- Testing
- DN1406131
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Healthy
A Study To Observe Safety And Blood Concentrations Of PF-06412562 During And Following The Oral Administration Of Multiple Doses Of PF-06412562 In Healthy Adult Volunteers
This study is designed to evaluate the safety and plasma concentrations of PF-06412562 in healthy volunteers following three times daily oral dosing of PF-06412562 for 14 days
- Trial name
- NCT01959594
- Testing
- 3 mg PF-06412562, 10 mg PF-06412562, 25 mg PF-06412562
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pfizer
Dysentery, Bacillary
A Study to Evaluate Safety and Immunogenicity of 1 Booster Dose of 1790GAHB Vaccine in Healthy Adults Primed With 3 Doses of 1790GAHB Vaccine in Study H03_01TP Compared to 1 Vaccination of 1790GAHB in Either Subjects Who Received Placebo in the Same Study or naïve Subjects Not Part of H03_01TP Study
GVGH Shigella Sonnei 1970GAHB is a vaccine aimed at preventing the disease caused by Shigella sonnei. A post-hoc analysis of subjects who participated in the parent study showed significantly different responses in subjects with…
- Trial name
- NCT03089879
- Testing
- GVGH Shigella sonnei 1790GAHB vaccine
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hypertension and Dyslipidemia
Study to Evaluate the Safety and Pharmacokinetics of CKD-331
Phase 1 study to evaluate the safety and pharmacokinetics of CKD-331 in healthy adult volunteers
- Trial name
- NCT05335044
- Testing
- CKD-331, EX5619
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Healthy Volunteers
Tolerance and Safety of an Oral Nutritional Supplement
This is an open label, non-randomized, interventional, single arm study.
- Trial name
- NCT05100901
- Testing
- MAG oil oral nutritional supplement (ONS)
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Volunteers
A Study of Dengue Vaccine in Healthy Children, Teenagers and Adults in India
The main aims of the study are to learn about side effects and a participant's immune response to Takeda's Dengue Vaccine when given twice within 3 months.
- Trial name
- NCT06060067
- Testing
- TDV
- Where
- 10 sites in India
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Takeda
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