Clinical trials: Healthy Adult Volunteers
Musculoskeletal Health, Healthy Adult Volunteers
The Effects of the Yi Jin Jing on the Muscles and Bones of Adults
Observation of the effects of Yi Jin Jing on the muscles and bones of adults
- Trial name
- NCT07753291
- Testing
- Yijinjing
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Pulmonary Tuberculosis
Phase 1 ID93 + GLA-SE Vaccine Trial in BCG-Vaccinated Healthy Adult Volunteers
The purpose of this study is to determine the safety, tolerability, and immunogenicity in BCG-vaccinated healthy adult subjects of an investigational vaccine being developed for the prevention of pulmonary tuberculosis.
- Trial name
- NCT01927159
- Testing
- ID93 + GLA-SE
- Where
- South Africa
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Access to Advanced Health Institute (AAHI)
Positional Nystagmus, Healthy Volunteers
Prevalence of Positional Nystagmus in a Population of Healthy Adults
To investigate the prevalence of positional nystagmus in a population of healthy Danish adults.
- Trial name
- NCT05554770
- Testing
- Examinations in a TRV chair
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Healthy Volunteer
A Study to Assess How Food Affects the Movement of Oral ABBV-101 Through the Body of Healthy Adult Participants
This study will assess the effect of food (high fat) on oral ABBV-101 and how ABBV-101 moves through the body in healthy adult participants
- Trial name
- NCT06887010
- Testing
- ABBV-101
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- AbbVie
Healthy Volunteers
A Study To Evaluate the Safety, Tolerability, And Pharmacokinetics Of PF-06266047 In Healthy Adult Subjects
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of PF-06266047 after first-time administration to healthy adult subjects.
- Trial name
- NCT02539550
- Testing
- PF-06266047
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteers
IPG1094 Phase I Study for China Healthy Participants
This Phase 1 open-label study enrolls 24 healthy Chinese adults to investigate the pharmacokinetics, safety and tolerability of oral IPG1094 tablets. The trial includes two parts.
- Trial name
- NCT07679113
- Testing
- IPG1094 Tablets
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nanjing Immunophage Biotech Co., Ltd
Healthy
Evaluation of Adhesion and Dermal Tolerability of EMSAM
Examine adhesive and dermal tolerability of EMSAm 6mg/24hr and 12mg/24hr in healthy elderly and non-elderly subjects.
- Trial name
- NCT00531596
- Testing
- EMSAM (Selegiline Transdermal System) 6mg/24Hr, EMSAM (Selegiline Transdermal System) 9mg/24Hr, EMSAM (Selegiline Transdermal System) 12mg/24hr
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Somerset Pharmaceuticals
Healthy Volunteers
A Study to Evaluate Safety, Tolerability, and Distribution of a Microdose of Radiolabeled BIIB067 (99mTc-MAG3-BIIB067) Co-administered With BIIB067 (Tofersen) to Healthy Adults
The primary objective of the study is to evaluate the distribution in the central nervous system (CNS) of a microdose 99mTc-MAG3-BIIB067 co-administered with unlabeled BIIB067 (Tofersen).
- Trial name
- NCT03764488
- Testing
- Tofersen, 99mTc-MAG3-BIIB067
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Biogen
Healthy Volunteer
A Study to Assess the Relative Bioavailability of Oral ABBV-932 in Healthy Adult Participants
This study will assess the relative bioavailability and effect of food on pharmacokinetics of ABBV-932 oral administration in healthy adult participants.
- Trial name
- NCT06849791
- Testing
- ABBV-932
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- AbbVie
Lichen Simplex Chronicus
A Phase I Clinical Trial to Evaluate the Single Dose Ascending and Food Effects of PG-033 in Healthy Adults
The goal of this study is to evaluate the safety, tolerability and pharmacokinetics (PK) profiles of single ascending oral doses(SAD) of PG-033 by directly comparing it with placebo.
- Trial name
- NCT07013097
- Testing
- PG-033
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Prime Gene Therapeutics Co., Ltd.
Healthy Volunteers
A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants
The purpose of this study is to evaluate the pharmacokinetics (PK) of xanomeline following administration of KarXT in CYP2D6 normal/extensive, intermediate, poor, and ultrarapid metabolizers.
- Trial name
- NCT07204418
- Testing
- Xanomeline/ Trospium Chloride
- Where
- 3 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Healthy Volunteer
Drug-drug Interaction Study of Ozanimod With Tyramine to Evaluate the Effect on Pressor Response
The purpose of this study is to evaluate the potential effect of ozanimod on pressor response when co-administered with oral tyramine in healthy adult subjects.
- Trial name
- NCT03694119
- Testing
- Phenelzine, Tyramine, ozanimod
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Celgene
Healthy Volunteers
A Phase I Study Comparing the Safety, Pharmacokinetics and Renal Effects of VRP-034 and Marketed Polymyxin B in Healthy Volunteers
This is a Phase 1, single-center, randomized, double-blind, active-controlled clinical study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and nephrotoxicity attenuation potential of VRP-034 compared with…
- Trial name
- VRP-034 (NCT07502144)
- Testing
- VRP-034 (Polymyxin B 500,000 IU), Commercially available Polymyxin B 500,000 IU (Poly-MxB)
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Venus Remedies Limited
Avian Influenza
A Safety and Immunogenicity Study of IVACFLU-A/H5N1
The study hypothesis was that two 0.5 mL doses of whole virion monovalent A/H5N1 influenza vaccine (IVACFLU-A/H5N1) adjuvanted with alum would be safe and well tolerated in healthy adults, and that at least one of the two doses…
- Trial name
- NCT02612909
- Testing
- IVACFLU-A/H5N1 vaccine
- Where
- 2 sites in Vietnam
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Institute of Vaccines and Medical Biologicals, Vietnam
Healthy Volunteers
Bioequivalence Study Comparing Two Tablet Formulations of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects
A bioequivalence and food-effect study comparing two tablet formulations of tebipenem pivoxil hydrobromide (TBPM-PI-HBr) in healthy adult subjects.
- Trial name
- NCT04421885
- Testing
- Tebipenem pivoxil hydrobromide (TBPM-PI-HBr) - Reference, Tebipenem pivoxil hydrobromide (TBPM-PI-HBr) - Test
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Spero Therapeutics
Healthy Volunteer, Immune Response
LC-Plasma on Immune Response and Reducing Symptoms of Upper Respiratory Infectious Diseases
The goal of this study is to evaluate the effects of LC-Plasma on the innate and acquired immune systems, including the activation of pDCs, which play a role in virus elimination, as well as to assess its efficacy in reducing…
- Trial name
- NCT06837961
- Testing
- LC-Plasma
- Where
- Australia
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Healthy Volunteer
Study to Assess How Different Oral Formulations of Ubrogepant Move Through the Body in Healthy Adult Participants
This study will assess how different oral formulations of ubrogepant move through the body in healthy adult participants under fasting and fed conditions.
- Trial name
- NCT07680686
- Testing
- Ubrogepant
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- AbbVie
Healthy Volunteers
Pharmacokinetics, Safety and Tolerability Study of AVT02 to EU-approved and US-licensed Humira (Adalimumab)
This study has been designed as a multicentre, randomised, double-blind study of AVT02 in healthy adult subjects. The study will assess the PK, safety and tolerability of AVT02 compared to EU-Humira and US licenced Humira…
- Trial name
- NCT03849313
- Testing
- Adalimumab
- Where
- 3 sites in Australia, New Zealand
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Alvotech Swiss AG
Hypertension and Dyslipidemia
Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-386 in Healthy Volunteers Under Fasting Conditions
This study is a randomized, open-label, single dose, crossover study to evaluate the pharmacokinetic profiles and safety of CKD-386 in healthy volunteers under fasting conditions.
- Trial name
- NCT05552495
- Testing
- CKD-386(4) F1, CKD-386(4) F2, D013, D326, D337
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Acid Reflux, Gastro Oesophageal Reflux Disease
A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting Conditions
The purpose of this study is to assess the effectiveness of Zegerid 20mg capsules and powder and Losec 20mg capsules in healthy volunteers under fasting conditions.
- Trial name
- NCT01710995
- Testing
- Zegerid, Losec
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Norgine
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