Clinical trials: Healthy Condition
Chronic Kidney Diseases, Healthy
Identification of P-cresyl Sulfate Producer Phenotype by Oral Tyrosine Challenge Test: Interactions Among Diet, Gut Microbiota, and Host Genome
Patients with chronic kidney disease (CKD) display a substantial increase in cardiovascular disease (CVD). Moreover, the prognosis of CVD in CKD is extremely poor.
- Trial name
- NCT04204174
- Testing
- Tyrosine, brand name: myprotein
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Acute Pain, Pain Perception
Effects of Transcutaneous Vagus Nerve Stimulation on Pain and Brain Activity in Healthy Adults
The goal of this clinical trial is to learn whether stimulating a nerve in the neck changes how much pain people feel. It also looks at whether this stimulation changes brain activity.
- Conditions
- Acute Pain, Pain Perception, Healthy Adult Participants
- Trial name
- NCT07827690
- Testing
- Active transcutaneous vagus nerve stimulation, Cold pressor test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- David A. Purger
Evaluate PK Profile, Evaluate PD Profile
A Study Testing the Effects of Different THC Doses on Psychological and Biological Function
The goal of this clinical trial is to learn how a investigational medicinal product (THC) affects psychological and physical responses in healthy adults with prior cannabis use experience.
- Conditions
- Evaluate PK Profile, Evaluate PD Profile, Healthy Adults, Safety and Tolerability in Healthy Volunteers
- Trial name
- DRATT (NCT07346690)
- Testing
- AVCN319301b (6mg), AVCN319301b (9mg), AVCN319301b (15mg)
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Calgary
HIV Infection, Infection, Human Immunodeficiency Virus
Healthy Volunteer Study To Assess The Bioavailability of GSK1265744 When Administered Orally Either When Fasted or Following a Meal.
To evaluate the single dose relative bioavailability of GSK1265744 10mg administered in either oral solution fasted, two 5mg tablets fasted, or two 5mg tablets following a moderate meal.
- Trial name
- NCT00812318
- Testing
- GSK1265744 10 mg oral solution, GSK1265744 5 mg tablet
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Dementia
The Effects of Music on ANS and Anxiety in Healthy Elderly and Persons With SCD
Subjective cognition decline (SCD) is considered as a risk factor of dementia and associates not only with further cognition deterioration but with a higher anxiety level.
- Trial name
- NCT04177160
- Testing
- Music, White noise
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Generalized Visual Field Contraction or Constriction
A Study to Determine the Location of the Blind Spot and the Macula-disc Centre Distance on a Fundus Photograph
The study is aimed to develop a new reaction-time based method for examining the visual field and to study the effect of refractive error on the magnification of a fundus photograph in order to evaluate the true size of a retinal…
- Trial name
- NCT01843582
- Where
- Finland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Childhood Obesity, Family
FamCe-HLP- Family-centered Obesity Management Program in Primary Care Settings
This clinical trial aims to compare the adiposity and weight status among mother-child dyads with overweight or obesity who receive the Fam-Ce-HLP intervention with the mother-child dyads with overweight or obesity who did not…
- Conditions
- Childhood Obesity, Family, Behavior, Health, Lifestyle, Healthy
- Trial name
- NCT06394882
- Testing
- Family-Centered Healthy Lifestyle Program (FamCe-HLP)
- Where
- 4 sites in Oman
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oman Ministry of Health
Insomnia
A Study to Evaluate Next Day Effects of MK-4305 on Driving Performance (MK-4305-035 AM1)
This is a study to evaluate next-day residual effects of MK-4305 on highway driving performance in healthy, non-elderly participants.
- Trial name
- NCT01311882
- Testing
- MK-4305 40 mg, MK-4305 20 mg, Zopiclone
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cardio Vascular Disease, Metabolic Syndrome (MetS)
Norwegian Mental Illness Heart Health Study
Norwegian patients with severe mental illnesses (SMI), such as schizophrenia spectrum or bipolar disorder, lose on average 10 years of life compared to mentally healthy individuals. Much of this gap is due to heart disease.
- Conditions
- Cardio Vascular Disease, Metabolic Syndrome (MetS), Severe Mental Disorder, Schizophrenia and Schizophrenia Spectrum Psychosis
- Trial name
- NORMI-Heart (NCT07085923)
- Testing
- Lifestyle Intervention
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Madeleine Elisabeth Angelsen
Postprandial Glycemia, Postprandial Insulinemia
A Human Clinical Trial Evaluating the Effect of MealShape™ on Blood Glucose Level Following Consumption of Standard Meal
The purpose of the study is to evaluate the effect of MealShape, a Ceylon cinnamon extract (Cinnamomum zeylanicum) on blood glucose and insulin response after consumption of a standard meal composed of white bread, in healthy…
- Trial name
- NCT02074423
- Testing
- MealShape cinnamon extract
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Dialpha
Healthy
Bioequivalence Study of Risperidone 1 mg Orally-disintegrating Tablets Under Fed Conditions
The purpose of this study is to determine the pharmacokinetics and bioequivalence of Risperidone formulations after administration of single doses to normal, healthy subjects under fed conditions.
- Trial name
- NCT01222923
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Diabetes Mellitus, Healthy Volunteers
Impaired Wound Healing in Diabetic Foot Ulceration
An observational study to gather information about people who may have certain abnormalities in skin microcirculation and muscle metabolism and to determine whether these abnormalities affect wound healing.
- Trial name
- EPC (NCT00739323)
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Hepatitis C, Chronic, Hepatitis C
Monotherapy Versus Placebo Over 14 or 17 Days in Healthy and Hepatitis C Infected Adults
This study represents the first administration of GSK625433 in humans. The study is designed to evaluate initial safety and tolerability in healthy adults as well as anti-viral activity in Hepatitis C(HVC) infected adults.
- Trial name
- NCT00439959
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Irritable Bowel Syndrome (IBS)
A Study To Investigate The Effect Of Solabegron (GW427353) On Gastrointestinal Transit In Healthy Volunteers
This study will test the hypothesis that GW427353, a beta-3 adrenergic agonist, retards the emptying of the colon and increases total colonic transit time.
- Trial name
- NCT00401479
- Testing
- Solabegron (GW427353)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Parkinson Disease
How the Loss of Dopamine and Dopamine-Restoring Medicines Affect Movement Performance
This study has two purposes: 1) to understand the effect of a decline of dopamine in the brain during normal aging and in patients with Parkinson's disease, and 2) to investigate how medicines used to treat Parkinson's disease…
- Trial name
- NCT00040196
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cognitive Impairment, Hereditary Spastic Paraplegia
Studying Cognition in SPG4
Comparing the cognitive levels of patients with SPG4 mutations to healthy controls.
- Trial name
- NCT03104088
- Testing
- CANTAB, MOCA
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Healthy Aging, Risk Reduction
Validation of the REMINDER Dementia Risk Reduction Program
Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies.
- Conditions
- Healthy Aging, Risk Reduction, Old Age; Dementia
- Trial name
- REMINDER (NCT05296980)
- Testing
- REMINDER, Brain health Psychoeducation
- Where
- Portugal
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Hepatic Insufficiency
A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.
The main purpose of this study is to evaluate how a medicine, LY3841136, works in participants with different levels of liver damage and in participants with healthy liver.
- Trial name
- NCT07401862
- Testing
- LY3841136
- Where
- 3 sites in United States, Hungary
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Schizophrenia
Phase I Study to Evaluate the Safety and Pharmacokinetics of Oral Doses of Anvylic-3288 in Healthy Subjects
This is a brief inpatient study to determine the safety of a new drug in healthy people.
- Trial name
- AVL3288 (NCT01851603)
- Testing
- AVL-3288
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Microbial Colonization, Small Intestinal Bacterial Overgrowth
High-fat Diet (HFD) and Small Intestinal Microbiome
The investigators aim to characterize the upper small intestinal microbiome in healthy conditions in dependency on feeding condition (starved vs.
- Trial name
- FATBOM (NCT07019142)
- Testing
- HFD
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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