Clinical trials: Healthy Eyes
Eye Infections, Bacterial
Ocular Tolerance, Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1.0, 1.5% in 48 Healthy Volunteers
To compare the ocular tolerance, the safety and the ocular pharmacokinetics of 3 concentrations (0.5% - 1.0% - 1.5%) and the vehicle of T1225 after one drop instillation
- Trial name
- NCT00357292
- Testing
- Azithromycin (T1225)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratoires Thea
Multiple Sclerosis, NMO Spectrum Disorder
A Study of LP-168 in Healthy Volunteers
This is a Phase I study designed to assess the safety, tolerability and pharmacokinetics of LP-168 in healthy human volunteers.
- Trial name
- NCT05432713
- Testing
- LP-168 tablet
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Guangzhou Lupeng Pharmaceutical Company LTD.
Eye Diseases
A Study of Laquinimod Eye-drops in Healthy Participants
This is a Phase 1 randomized, double-masked, placebo-controlled study performed with healthy participants to assess the safety and tolerability of laquinimod eye-drops.
- Trial name
- NCT05187403
- Testing
- Laquinimod
- Where
- Austria
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Active Biotech AB
Healthy
Study Assessing Ocular and Systemic Safety of AR-13324 in Healthy Volunteers
The purpose of this study is to assess systemic safety and absorption of AR-13324 in healthy volunteers.
- Trial name
- NCT01997879
- Testing
- AR-13324 Ophthalmic Solution, 0.02%
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Aerie Pharmaceuticals
Healthy Volunteers
Study of the Safety of USB005 in Healthy Volunteers
This study will evaluate the safety, tolerability and pharmacokinetics of USB005 (aclerastide) Ophthalmic Solution.
- Trial name
- NCT03615196
- Testing
- USB005 (aclerastide) Ophthalmic Solution
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- US Biotest, Inc.
Mydriasis, Dilation
Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis
The objectives of this study are: To evaluate the efficacy of Nyxol to expedite the reversal of pharmacologically-induced mydriasis across multiple mydriatic agents with an emphasis on phenylephrine To evaluate the efficacy of…
- Trial name
- NCT04620213
- Testing
- Phentolamine Ophthalmic Solution 0.75%
- Where
- 12 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Opus Genetics, Inc
Normal Healthy Subjects With No Known Ocular Diseases, Glaucomatous Eyes
Maestro Agreement and Precision Study II
Assess the repeatability and agreement of the Optic Disc Parameters, Retinal Nerve Fiber Layer (RNFL) Thickness, Full Retinal Thickness, and Ganglion Cell Thickness between the Maestro and iVue OCT devices.
- Conditions
- Normal Healthy Subjects With No Known Ocular Diseases, Glaucomatous Eyes, Eyes With Retinal Diseases
- Trial name
- NCT02376868
- Testing
- 3D OCT-1 Maestro, iVue
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Open Angle Glaucoma, Ocular Hypertension
A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular Hypertension
This is a Phase I/II stage to investigate the safety, tolerability, and ocular hypotensive efficacy of TO-O-1001 in healthy volunteers and patients with Open-Angle Glaucoma or Ocular Hypertension.
- Trial name
- NCT05456724
- Testing
- TO-O-1001
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Theratocular Biotek Co.
Conjunctivitis, Conjunctivitis, Bacterial
Safety and Tolerability of the PRO-174 Versus Sophixín Ofteno®, on the Ocular Surface of Healthy Subjects
Phase I clinical trial, to evaluate the safety and tolerability of the ophthalmic solution PRO-174 versus Sophixín Ofteno®, elaborated by Laboratorios Sophia, S.A. of C.V.
- Trial name
- PRO-174/I (NCT03519516)
- Testing
- PRO-174, Sophixín Ofteno®
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Healthy
Dose Tolerance Study After Ocular Administration of Tiotropium in Healthy Male Volunteers
Safety and tolerability after ocular administration
- Trial name
- NCT02177305
- Testing
- 0.02 mcg tiotropium solution, 0.04 mcg tiotropium solution, 0.08 mcg tiotropium solution
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim