Clinical trials: Healthy Eyes
Healthy Adolescents
EyeBreathe: A Mixed Reality Game With Eye Tracking and Breathing Biofeedback for Adolescent Basketball Players - A Randomised Controlled Trial
This randomised controlled trial will evaluate the effects of integrating a standalone mixed-reality (MR) breathing and eye-gaze training intervention (EyeBreathe) into regular basketball practice for adolescent athletes in…
- Trial name
- EyeBreathe-RCT (NCT07871331)
- Testing
- Breathing MR
- Where
- 2 sites in Latvia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Healthy
Fluorophotometry Evaluation of Lubricant Eye Drops
The objective of this study is to evaluate the safety and efficacy of exaggerated use of Lubricant Eye Drops in a population of normal subjects by measuring corneal epithelial permeability to fluorescein.
- Trial name
- NCT00347854
- Testing
- Systane Free lubricant eye drops, Visine Tears Lubricant Eye Drops, Refresh Liquigel Lubricant Eye Drops
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Healthy
Reproducibility of Cirrus Optical Coherence Tomography Measurements
In this study the reproducibility of optical coherence tomography measurements should be evaluated.
- Trial name
- NCT00643422
- Testing
- Cirrus™ HD-OCT, Carl Zeiss Meditec AG
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Healthy Eyes, Retinal Diseases
Clinical Investigation of a New Version of MAIA Microperimeter on Healthy Subjects and Patients With Retinal Pathology
The purpose of this pre-market, monocentric cross-sectional study is to evaluate the clinical usefulness of a new version of the MAIA device (MAIA) through an agreement with the established version of the MAIA microperimeter…
- Trial name
- NCT06071546
- Testing
- MAIA
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Centervue SpA
Healthy Eyes
Evaluation of the Signal to Noise Ratio at Various Retinal Layers
Compare the signal to noise ratio of each device at various retinal layers.
- Trial name
- NCT02982174
- Testing
- 3D OCT-1 Maestro, DRI OCT Triton
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Cataract
Dynamic Light Scattering for Studying Lens Aging and Cataract Formation
This study will use dynamic light scattering (DLS) technology to study normal lens aging and early cataract formation. Cataract is a clouding of the lens that interferes with the passage of light to the retina, impairing visual…
- Trial name
- NCT00081991
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Glaucoma, Visual Field Defect
Visual Field Analysis With Artificial Intelligence
The purpose of this study is to analyze visual field data from healthy participants. This data will be used to develop and optimize a new visual field perimeter test.
- Trial name
- VFAAI (NCT06920290)
- Testing
- Visual Field Perimeter Optimized with Eye Gaze Capture and Artificial Intelligence
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sight Intelligence Engineering Corporation
Healthy
The Influence of Energy Drinks on the Blood Oxygenation Concentration of the Optic Nerve
The present proposal investigates the influence of energy drinks on the blood oxygenation concentration of the optic nerve on healthy subjects.
- Trial name
- NCT01827150
- Testing
- Redbull, energy drink
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Healthy
Characterization of the Edge of Soft Contact Lens and Its Interaction With Ocular Surface
The goal of this study is to look at contact lens on the eye and its interaction with the eye during wearing.
- Trial name
- NCT00707291
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Miami
Retinitis Pigmentosa, Retinal Degeneration
The Effects of Cannabis on Visual Functions in Healthy and Retinitis Pigmentosa Patients
Medical Marijuana is used widely, and its effects on the visual system and the function of the retina have not been investigated thoroughly.
- Conditions
- Retinitis Pigmentosa, Retinal Degeneration, Cannabis
- Trial name
- NCT03078309
- Testing
- cannabis
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Myopia
Long Term Effects of Multifocal Orthokeratology on Corneal and Choroidal Structures in Healthy Subjects With Myopia- A Pilot Study
Orthokeratology has the benefit for slowing down myopia progression and enabling unaided vision during the day. To investigate proposed possible changes of conventional and multifocal orthokeratology in the cornea and choroid…
- Trial name
- NCT02700295
- Testing
- Orthokeratology lens
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy, Normoxia
Measurement of Retinal Blood Flow, Retinal Oxygenation and Retinal Oxygen Extraction in Healthy Subjects During Normoxia and Systemic Hyperoxia
The inner retina is crucially dependent on an adequate retinal blood supply. When the retina becomes ischemic and hypoxic this results in severe vision loss due to retinal neovascularization.
- Conditions
- Healthy, Normoxia, Systemic Hypoxia
- Trial name
- NCT00914407
- Testing
- Oxygen
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dry Eye Syndromes
Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers
The "dry eye syndrome" DES is a highly prevalent ocular disease, in particular in the elderly population. One mainstay of therapy for patients suffering from DES is the use of topically administered lubricants.
- Trial name
- NCT01015209
- Testing
- Chitosan- N- Acetylcysteine eye drops
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Retinal Disease, Healthy Population
Multifocal Electroretinogram in Normal Egyptian Population
Studying normal subjects to create unique normal database for multifocal electroretinogram (mf-ERG) in specific population.
- Trial name
- NCT05323032
- Testing
- Multifocal electroretinogram (mf-ERG) by electroretinogram device
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Benha University
Healthy
Study of Eye Movements as Markers of the Physiological, Cerebral and Cognitive State of Healthy Subjects
The goal of this study is the multimodal exploration via eyetracking, MRI and EEG data of ocular movements and the corresponding brain activation during ecologic visual stimulation in the healthy population.
- Trial name
- EyeProxy (NCT04325971)
- Testing
- Neuroimaging
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy, Sicca Syndrome
A Longitudinal, Observational Biomarker Study in Participants With Primary Sjogren's Syndrome
The main objective of the study is to characterize the gene expression in immune and epithelial cells in salivary gland biopsy samples and blood of pSS (primary Sjögren's syndrome) and non-pSS participants including healthy…
- Conditions
- Healthy, Sicca Syndrome, Sjögren's Syndrome
- Trial name
- NCT02422407
- Testing
- Biopsy
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biogen
Glaucoma, Retinal Disease
Study to Compare Kowa OCT Bi-μ and the Optovue iVue 100
This study is a prospective comparative study to gather pilot agreement and precision data in normal subjects, subjects with glaucoma, and subjects with retinal disease.
- Conditions
- Glaucoma, Retinal Disease, Healthy
- Trial name
- OCT (NCT03505567)
- Testing
- KOWA OCT Bi-µ, Optovue iVue 100
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kowa Research Institute, Inc.
Healthy, Major Depressive Disorder (MDD)
Neurobiological and Genomic Predictors of Relapse in Depression
The goal of this observational study is to test whether the discontinuation of antidepressant medications for patients with depression can be decided after the normalization of biological parameters.
- Trial name
- MDD (NCT07328373)
- Testing
- Antidepressant Medications
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Mehmet Kemal Arikan
Glaucoma
Short Term Comparative Study of Xalatan With Benzalkonium Chloride vs. Travatan Z Without Benzalkonium Chloride in Healthy Volunteers
Compare the effect of Xalatan with benzalkonium chloride on the ocular surface to those effects observed with Travatan Z without benzalkonium chloride after a single dose
- Trial name
- NCT00468988
- Testing
- Travatan® Z, Xalatan®
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Healthy
Role of Endothelin-1 in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans
Autoregulation is defined as the ability of a vascular bed to adapt its vascular resistance to changes in perfusion pressure. In the eye, several studies have reported that retinal blood flow is autoregulated over a wide range of…
- Trial name
- NCT00915070
- Testing
- BQ-123, Physiological saline solution, Laser Doppler Flowmetry
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna