Clinical trials: Healthy Female Adults
Healthy
Pharmacokinetics of Decursin/Decursinol Angelate (CognIQTM)
This study is to investigate how human bodies absorb and metabolize two herbal drugs. The information is critical for drug development and could not be obtained from any other studies using animals.
- Trial name
- NCT02114957
- Testing
- 800mg dietary supplement CognIQTM (4 capsules) by oral at hour 0
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Chronic Kidney Diseases
A Mass Balance Study of [14C]HRS-1780 in Healthy Adult Male Subjects
The study aims to evaluate the pharmacokinetics, mass balance recovery, metabolite profile and metabolite identification of [14C]HRS-1780 following an oral single dose in healthy adult male participants.
- Trial name
- NCT07557407
- Testing
- [14C]HRS-1780
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
The Focus of the Study is to Investigate Reversible Effects of Combined Oral Contraceptive Use on Serotonergic Neurotransmission, Healthy Adult Females
Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission
The goal of this study is to learn about potential reversible effects of combined oral contraceptive (COC) use on the serotonergic brain system.
- Trial name
- REVERSE (NCT07511439)
- Testing
- Discontinuation of 2nd generation combined oral contraceptive use, Continuation of 2nd generation combined oral contraceptive use
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy Adults
FueL Use During eXercise in Males and Females
This study will investigate whether pre-exercise nutrition influences sex differences in fuel utilization during endurance exercise.
- Trial name
- FLUX (NCT07829237)
- Testing
- Pre-exercise carbohydrate beverage, Pre-exercise protein beverage, Fasted control beverage
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Adults
Safety, Tolerability, Pharmacokinetics and Food Effects of Oral EC5026 in Healthy Subjects
The purpose of the study is to provide safety, tolerability, pharmacokinetics and food effects data of a single 8 mg oral dose of EC5026 in healthy subjects.
- Trial name
- NCT04908995
- Testing
- EC5026 oral tablet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- EicOsis Human Health Inc.
Tuberculosis
TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study)
This is a randomized, open-label, cross-over study comparing the bioequivalence of bedaquiline administered in whole tablet form versus bedaquiline administered in crushed (experimental) form in healthy adult volunteers.
- Trial name
- NCT03032367
- Testing
- bedaquiline
- Where
- South Africa
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Healthy Female
A Study of Milvexian in Healthy Adult Females
The purpose of this study is to measure the effect of milvexian given for approximately 2 weeks on (a) how the liver metabolizes other drugs (in this case one called midazolam), and (b) the pharmacokinetics (the way the body…
- Trial name
- NCT05706753
- Testing
- Milvexian, Midazolam, Ethinylestradiol
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Diabetes Mellitus, Type 2
An Evaluation of the Pharmacokinetics of an Oral Contraceptive (Brevicon) When Co-administered With Albiglutide .
This study will be an open-label study to evaluate the effect of albiglutide on the pharmacokinetics and pharmacodynamics of a standard oral contraceptive regimen (Brevicon).
- Trial name
- NCT01077505
- Testing
- albiglutide, Oral contraceptive (Brevicon)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Diet, Nutrition Aspect of Cancer
Metabolism and Absorption of Anthocyanins From Extract and Whole Blueberry Powder Confections in Healthy Adults
This trial studies how well a group of compounds found in blueberries called anthocyanins are absorbed into the body from 2 different types of blueberry confections (blueberry extract and whole blueberry powder).
- Trial name
- NCT04329962
- Testing
- Blueberry Powder Food Product, Dietary Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Healthy Volunteers
Evaluate the Pharmacokinetics of a Combined Oral Contraceptive (COC) With and Without Obicetrapib
A study to evaluate the impact of Obicetrapib on the PK levels of Drospirenone and Ethinyl Estradiol (COC) in 30 adult female, healthy volunteers.
- Trial name
- NCT06250205
- Testing
- Obicetrapib, Obicetrapib + Drospirenone / Ethinyl Estradiol (COC), Drospirenone / Ethinyl Estradiol (COC)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NewAmsterdam Pharma
Drug Interaction Potentiation
A Drug-Drug Interaction Study of Warfarin and PA21
The purpose of this study is to determine if Warfarin is affected by PA21.
- Trial name
- NCT01477424
- Testing
- PA21, Warfarin
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Vifor Pharma
Healthy Volunteer, Renal Impairment
Study of AT-527 in Subjects With Normal and Impaired Renal Function
Study of AT-527 in Subjects with Normal and Impaired Renal Function
- Trial name
- NCT05618314
- Testing
- AT-527, AT-527 and Probenecid
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Atea Pharmaceuticals, Inc.
Diabetic Nephropathy
Safety, Tolerability, and Pharmacokinetics (PK) of CTP-499
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of CTP-499 following single dose administration.
- Trial name
- NCT01328821
- Testing
- CTP-499
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Concert Pharmaceuticals
Mass Balance Recovery
Study in Healthy Adult Female Subjects
An Open Label Phase 1 Study in Healthy Adult Female Subjects to Determine the Mass Balance Recovery, Absorption, Metabolism, and Excretion of [14C] D-0502 Following Single Oral Dose Administration
- Trial name
- NCT05339633
- Testing
- [14C]-D-0502
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- InventisBio Co., Ltd
Bioequivalance, Post-menopause
An Open-label, Randomized, Single-dose, Two-treatment, Four-period, Fully Replicate Crossover Bioequivalence Study in Healthy Female Adult Participants Under Fasting Conditions Comparing the Test Product, Prontogest Solution for IM Injection With the Reference Product, Progesterone Injection
Bioequivalence study of two injectable formulation of progesterone in healthy post-menopausal women
- Trial name
- Prontogest (NCT07495007)
- Testing
- Progesterone IM of 100 mg
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Zi Diligence Biocenter
Healthy Adult Male and Female Volunteers
Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants
This study will be conducted to evaluate the relative bioavailability, pharmacokinetics, safety, and tolerability of AVP-923 (dextromethorphan hydrobromide [DM] and quinidine sulfate [Q] capsules) when the contents of a capsule…
- Trial name
- NCT03381664
- Testing
- AVP-923
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Avanir Pharmaceuticals
Menstrual Discomfort
Probiotic and Gastrointestinal Symptoms Due to Menstruation in Healthy Women
In this double blind, parallel study, female participants who are on an oral contraceptive will consume either a probiotic or placebo supplement for approximately 8 weeks.
- Trial name
- NCT04457401
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Florida
ADHD, Predominantly Hyperactive - Impulsive, Behavior Problems, Child
Triple P forADHD Children's Mothers, Education of Behavioral Problems, and Change in Mothers' Attitude
The goal of this clinical trial is to investigate whether the Triple P program will reduce behavioral problems for ADHD children, improve mothers' sense of competency, and improve their attitudes The main questions it aims to…
- Conditions
- ADHD, Predominantly Hyperactive - Impulsive, Behavior Problems, Child, ADHD - Attention Deficit Disorder With Hyperactivity, Healthy Adult Females
- Trial name
- (ADHD) (NCT07069621)
- Testing
- Triple p level parenting program
- Where
- Palestinian Territories
- Volunteers
- 67 people
- Sponsor
- Palestine Polytechnic University
Healthy
A Food Effect Study With ZN-c5 in Healthy Post-Menopausal Subjects
This is a single-center, randomized, open-label, two-period, 2-way crossover food effect study to determine the comparative bioavailability of ZN-c5 under fed and fasting conditions, following single-dose administration of ZN-c5…
- Trial name
- NCT04561752
- Testing
- ZN-c5
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zeno Alpha Inc.
Healthy
The Dose-response "Pilot" Study of Topically Delivered Clobetasol Propionate Lotion in Healthy Adult Subjects
To determine the dose-response relationship for Clobex TM (clobetasol propionate) Lotion, 0.05%. This information will be used to estimate the ED50, D1, D2 parameters for use in a full bioequivalence study.
- Trial name
- NCT00864240
- Testing
- Clobex TM (Clobetasol) 0.05% Lotion, single exposure
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.