Clinical trials: Healthy Individuals.
Cognitive Impairment
Impact of Resistance Training Volume on Cognitive Function and Physical Performance in Cognitively Impaired Individuals
This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, inflammatory markers, lipid profile, glycemic status, muscle damage, hemodynamic response, and…
- Trial name
- TRAIN4BRAIN (NCT06528951)
- Testing
- Control Phase ( 6Weeks), 15% increase in resistance training volume (10 Weeks), 30% increase in resistance training volume (10 Weeks)
- Where
- Portugal
- Volunteers
- 69 people
- Sponsor
- University of Beira Interior
Cognitive Functioning of Healthy Individuals
Norms Expansion and Validation for IntelliSpace Cognition
This study aims to expand the normative dataset for Philips IntelliSpace Cognition to include ages 18-49 and 80+ and aims to validate two new digital tests.
- Trial name
- NCT04729257
- Testing
- Philips IntelliSpace Cognition (ISC)., Paper-Pencil Tests.
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Healthy
A Study to Examine the Glycemic Response of Corn and Soy Tortillas in Healthy Individuals
Tortillas are a staple food in several cultures and are widely used to make tacos, burritos, and enchiladas. These foods are gaining a significant segment of the North American fast food and restaurant industry.
- Trial name
- SOYT-2013 (NCT01828671)
- Testing
- Oral Glucose Solution 296 mls, Corn Tortilla, Low Soy Flour Corn Tortilla
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Healthy
Effect of Surface Electrical Stimulation on Movement of the Larynx
This study will examine whether surface electrical stimulation on the skin of the throat will: 1) move the larynx (voice box); 2) move the vocal folds in the larynx; and 3) cause less movement of the larynx when applied during…
- Trial name
- NCT00104000
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy
Phase I/II Trial of Modified Vaccinia Virus Ankara (MVA) Vaccine Against Smallpox
This study will test the safety of an experimental vaccine called modified vaccinia virus ankara (MVA) and determine if it confers protection against the smallpox virus (variola).
- Trial name
- NCT00053742
- Testing
- Modified Vaccinia Virus Ankara TBC-MVA
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Mitochondrial Disease
Calf Muscle Strength in Mitochondrial Diseases
Mitochondrial disorders are a group of inherited disorders causing malfunctional mitochondria. Mitochondria are found in every cell of the body, and the disorders therefore give symptoms from every tissue, especially those with…
- Trial name
- CMSMD (NCT02678637)
- Testing
- MRI and muscle dynamometer
- Where
- Denmark
- Volunteers
- 37 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Multiple Sclerosis
Motor Evoked Potentials With Modified Facilitation Technique
Investigating the change in Test- Retest- reliability in healthy individuals when applying a modified easy to use facilitation technique compared to standard facilitation technique and analyzing sensitivity and specificity in…
- Trial name
- EP-F (NCT03646929)
- Testing
- MEP using standard facilitation technique, MEP using modified facilitation technique
- Where
- Switzerland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy
Relationship Between Modified Closed Kinetic Chain Upper Extremity Stability Test and Shoulder Endurance Test in Young Active and Sedentary Individuals
This study is planned to examine the relationship between Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST) performance with Posterior Shoulder Endurance Test in healthy young adults.
- Trial name
- NCT06571435
- Testing
- Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST), and Posterior Shoulder Endurance Test
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Healthy
Effect of Cervical Spinal Stabilization Exercise Programs by Magnetic Resonance Imaging in Healthy Individuals
The aim of this study was to investigate the morphological changes in the neck muscles of cervical spinal stabilization exercises focused on flexor and extensor muscles applied to healthy individuals.
- Trial name
- NCT03856008
- Testing
- Exercises focused on flexor muscles, Exercises focused on extensor muscles
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Individuals
Application of Photogrammetry for Manual Skills Training in Undergrad Physiotherapy Students
Education research shows that healthcare professional training can be made more efficient and effective with the integration of simulation technology.
- Trial name
- NCT03368508
- Testing
- Simulating video, Conventional video
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Technology
SARS-CoV-2 Infection, COVID-19
A Study to Learn About New COVID-19 RNA Vaccine Candidates in COVID-19 Vaccine-Experienced Healthy Individuals
The purpose of this clinical trial is to learn about the safety, tolerability and immunogenicity of BNT162b RNA-based SARS-CoV-2 vaccine candidates in adults to prevent COVID-19.
- Trial name
- NCT05472038
- Testing
- BNT162b5 Bivalent (WT/OMI BA.2), BNT162b2 Bivalent (WT/OMI BA.1), BNT162b2 Bivalent (WT/OMI BA.4/BA.5)
- Where
- 31 sites in United States
- Volunteers
- 1,453 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Psychological Well-Being, Oxidative Stress
A Study to Assess the Efficacy of CaroRite™ on Psychological Well-being, Oxidative Stress and Quality of Life in Healthy Individuals
The present study is a randomized, placebo-controlled, double-blind clinical study in which 94 individuals will be screened, and considering a screening failure rate of 20%, approximately 76 participants will be randomized in a…
- Conditions
- Psychological Well-Being, Oxidative Stress, Quality of Life
- Trial name
- NCT05931315
- Testing
- CaroRite™
- Where
- 4 sites in India
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Sedentary Lifestyle
Polarized Aerobic Training and Vascular Adaptations in Apparently Healthy Individuals
This randomized controlled trial will investigate the effects of a 6-week polarized aerobic training intervention on vascular and cardiorespiratory function in apparently healthy sedentary adults aged 30-50 years.
- Trial name
- ACT-ON-CHRONIC (NCT07665632)
- Testing
- Polarized Aerobic Training
- Where
- Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Coronary Disease, Coronary Arteriosclerosis
Effects of a Healthy Nordic Diet on Atherosclerosis in Patients with Coronary Heart Disease
Diet can play a key role in atherosclerosis and coronary heart disease (CHD), but little interventional data exists, and the mediators of possible anti-atherosclerotic effects of diet are unclear.
- Conditions
- Coronary Disease, Coronary Arteriosclerosis, Myocardial Infarction, Chronic Coronary Syndrome
- Trial name
- NORDHEART (NCT06701968)
- Testing
- Healthy Nordic Diet, Usual Care
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Uppsala University
Healthy Volunteers From Racial/Ethnic Minority Populations
EXPLORER PET/CT: Evaluation of Healthy Individuals From Racial/Ethnic Minority Populations
The objective of this pilot study is to collect preliminary data using total body scans on a new, first of its kind, FDA 510k-cleared positron emission tomography/computed tomography (PET/CT) scanner, called EXPLORER.
- Trial name
- NCT04812080
- Testing
- EXPLORER PET/CT
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Memory Decline, Healthy Subjects
In-Person Recruitment of Individuals to the Alzheimer's Prevention Trial (APT) Webstudy
Women, older adults, individuals from communities of color, particularly Black and Latino persons, and individuals with lower socioeconomic status are historically underrepresented in clinical research.
- Trial name
- FIND-AD Aim 2 (NCT07218120)
- Testing
- Financial Incentive, Active Comparator #1
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Patients With Stable Coronary Artery Disease
Acute Hemodynamic and Biological Effects of ECP and Exercise
The purpose of this study in humans with stable coronary artery disease (CAD) treatable by percutaneous intervention (PCI) is to evaluate the efficacy of Enhanced External Counterpulsation (EECP) with regard to coronary…
- Trial name
- NCT02014090
- Testing
- Hemodynamic and biological measurements
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy Volunteers (HV)
Examining the Effects of Reformer Pilates Exercises on Physical Fitness and Cognitive Functions in Healthy Individuals
Pilates is an exercise method that aims to increase body awareness and improve physical fitness through controlled movements based on mind-body integration.
- Trial name
- NCT07134517
- Testing
- Pilates exercise
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pancreatic Cancer
A Case-control Study Comparing Glycaemic Control in Pancreatic Cancer Patients vs Healthy Matched Individuals.
The aim of this study is to continuously monitor blood glucose concentrations for a 7-day period in pancreatic cancer patients whilst undergoing their typical daily routines and to compare this to age matched healthy individuals.
- Trial name
- PanCanCGM (NCT05583890)
- Testing
- Continuous glucose monitors, Activity tracker, Food Diary
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Lipid Disorder, Systemic Inflammatory Response
Evaluation of the Consumption of Lupins in Brine on Metabolic Markers in Healthy Individuals
The aim of the project was the evaluation of the effects of the consumption of different amounts of lupins in brine on lipid, glucose, inflammatory, oxidative stress, gut microbiota profile and (epi)genetic markers in healthy…
- Trial name
- SUPERLUPINO (NCT06595082)
- Testing
- 4-week lupins in brine consumption, 4-week lupins in brine consumption and dietary suggestion
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Teramo