Clinical trials: Healthy Individuals.
Healthy Aging, Risk Reduction
Validation of the REMINDER Dementia Risk Reduction Program
Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies.
- Conditions
- Healthy Aging, Risk Reduction, Old Age; Dementia
- Trial name
- REMINDER (NCT05296980)
- Testing
- REMINDER, Brain health Psychoeducation
- Where
- Portugal
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Obesity
Follistatin Levels in Metabolically Healthy and Unhealthy Obese Individuals
There is no clear boundary on which obese individuals should be considered metabolically healthy and which should be considered metabolically unhealthy.
- Trial name
- NCT06229899
- Testing
- Serum follistatin levels
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Respiratory Physiology
Expiratory Pressure in Healthy Individuals
The present study aims at enhancing our understanding of the influence of the mouthpiece configuration on the amplitude of oral pressures generated during a maximum expiratory pressure maneuver and on the neuromuscular…
- Trial name
- NCT06435793
- Testing
- MEP measurement - Surface EMG
- Where
- Belgium
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Laboratory of Movement, Condorcet, Tournai, Belgium
Metabolism and Nutrition Disorder
Metabolic and Functional Impact of Various Breakfast Models
In the present study the investigators compared the hormonal and metabolic effects of three meal loads very popular among Italian eating habits, both in the resting- and exercising state.
- Trial name
- NCT03240757
- Testing
- Breakfast, exercise
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Ospedale San Donato
Aging
Participatory Evaluation (of) Aging (With) Rapamycin (for) Longevity Study
This is a randomized, placebo-controlled trial into the safety and efficacy in reducing clinical measures of aging in an older adult population.
- Trial name
- PEARL (NCT04488601)
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- AgelessRx
Healthy Individuals
Effects of BLa80 and LRa05 on the Gut Microbiota Metabolite Profile of Healthy Individuals
Gut microbiota play a key role in polyphenol metabolism, participating in the breakdown of dietary components and producing various small molecule metabolites that affect human health.
- Trial name
- NCT07287306
- Testing
- BLa80, LRa05
- Where
- China
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Histamine, Cowhage
Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals
This project aims to investigate the relationship between different dimensions of catastrophizing (rumination, magnification, and helplessness) as well as some specific personality traits related to catastrophizing tendencies…
- Trial name
- NCT06340438
- Testing
- Histamine, Cowhage
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Basic Physiology, Brain Stimulation
Transcranial Direct Current Stimulation (tDCS) in the Primary Motor Cortex in Healthy Individuals
The main aim of this study is to assess the short-term effects of active-tDCS (a-tDCS) on the M1 regarding sensorimotor variables such as discriminative sensation, pressure pain threshold and electromyographic activity compared…
- Trial name
- NCT04148547
- Testing
- Sooma transcranial direct current stimulation device
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Frail Elderly
Pilot Study of Virtual Gait Training in Older Adults
Older individuals suffer from falls and fear of falling. The purpose of this study was to determine the effectiveness of a novel virtual gait training on walking performance and fear of falling in older adults, and to evaluate…
- Trial name
- NCT01607736
- Testing
- Virtual Gait Training
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Depression Disorder, Healthy
The Neural Representation of Self in Depression Patients
To be aware of oneself as a unique entity in the world occurs early in human development and is the prerequisite of normal social functioning.
- Trial name
- NCT03551041
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Beijing Normal University
Healthy
Exposure to the Aerobic Training Stimulus in Healthy Individuals
Fitness is an important determinant for health and influenced by using large muscles. Muscles respond to training. We want to know if adding arm exercise to leg exercise can provide a better training session for healthy…
- Trial name
- O2MVPaA (NCT06467227)
- Testing
- exercise modality
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- West Park Healthcare Centre
Periodontitis, Panoramic Radiography
Fractal and Morphometric Analysis of Mandibular Bone in Periodontitis
This retrospective study aims to evaluate the differences in mandibular bone structure between individuals with periodontitis and healthy controls using panoramic radiographs.
- Trial name
- PBFM (NCT07209579)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Periodontitis
IL-6, IL-17 and IL-35 Levels in the Gingival Crevicular Fluid of Patients With Periodontitis and Healthy Controls
Periodontitis is an inflammatory disease characterized by periodontal tissue destruction caused by bacterial infection. The immune response plays an important role in the progression of periodontitis.
- Trial name
- NCT05306860
- Testing
- No intervention was applied to the groups the samples will be collected in terms of the diagnosis (periodontitis, healthy)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
SARS-CoV2 Infection
Evaluation of Efficacy, Safety and Immunogenicity of GX-19N in Healthy Individuals Who Have Received COVID-19 Vaccines
The purpose of this study is to evaluate the efficacy, safety and immunogenicity of GX-19N in healthy individuals who have received one of COVID-19 vaccine authorized for emergency use.
- Trial name
- NCT05067946
- Testing
- GX-19N
- Volunteers
- healthy volunteers welcome
- Sponsor
- Genexine, Inc.
Healthy Individuals, Arterial Hypertension
The Influence of Aircraft Noise Exposure on Renal Hemodynamic in Healthy Individuals
Epidemiological studies have found a link between aircraft noise exposure and increased incidence of arterial hypertension and thus cardiovascular disease.
- Trial name
- LÄRM (NCT02783456)
- Testing
- Noise, Silence
- Where
- Germany
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Respiratory Problems
The Effect of Hypermobility Healthy Individuals
Benign Joint Hypermobility Syndrome is a hereditary connective tissue problem characterized by the emergence of multiple musculoskeletal problems in hypermobile individuals without a systemic rheumatologic disease.
- Trial name
- NCT04208022
- Testing
- Respiratory evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Kültür University
Healthy Individuals
Reliability of Elbow Flexion and Extension Strength Measurement Protocols Using a Hand-held Dynamometer
The aim of the study was to investigate the intra-rater and inter-rater reliability of elbow strength measurement procedures performed in different body postures and shoulder and elbow positions using a hand-held dynamometer in…
- Trial name
- NCT04352673
- Testing
- Elbow flexion and extension strength measurements using a hand-held dynamometer
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Healthy Individuals (Controls)
Effects of Combined Exercise Training Modality
This study aims to investigate the effects of combined Inspiratory Muscle Training and aerobic exercise on diaphragm and pulmonary functions, respiratory muscle function, performance, and body composition
- Trial name
- NCT06742372
- Testing
- combined inspiratory and aerobic exercise training, aerobic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gazi University
MCG Reference Intervals Determination for Healthy Adults, Health, Subjective
Determination of MCG Reference Intervals in Healthy Individuals
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting cardiac abnormalities. However, the results of MCG cannot be evaluated without defined reference intervals.
- Trial name
- NCT06198777
- Testing
- Magnetometer
- Where
- China
- Volunteers
- 2,396 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Healthy
Effects of Sage Extracts on Cognitive Function During Aerobic Exercise
Extracts of sage have been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has clearly demonstrated the possible effects in healthy individuals in…
- Trial name
- NCT04804657
- Testing
- Sage extracts Cognivia
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Burgundy