Clinical trials: Healthy Individuals.
Healthy Aging, Lifestyle-related Condition
Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity
The prevalence of age-related chronic diseases (like obesity, type 2 diabetes and cardiovascular diseases) is mounting worldwide, reaching pandemic proportions.
- Conditions
- Healthy Aging, Lifestyle-related Condition, Metabolic Diseases
- Trial name
- RESTORENAD (NCT06425042)
- Testing
- Nicotinamide Riboside (NR)
- Where
- Chile
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Finis Terrae University
Aging, Aging Well
Electromagnetic Field Protection Device Use Impact in Healthy Volunteers
This is a prospective, single group, self-controlled study to evaluate the clinical and molecular impact of continuous in-home resonance-based electromagnetic field (EMF) protection device usage in healthy individuals.
- Trial name
- NCT05001646
- Testing
- In-home resonance-based electromagnetic field protection device
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- TruDiagnostic
Parkinson's Disease with Cognitive Impairment, Healthy Elderly
Effectiveness of Attention/executivefunctions Training on Prospective Memory Abilities of Parkinson's Disease Subjects with Mild Cognitive Impairment and Healthy Aged Individuals: a Placebo-controlled Study with a Combined Immersive Virtual Reality and Telemedicine Approach
The goal of this randomized controlled trial is to evaluate the efficacy of attention and executive function training on prospective memory (PM) and executive functions in patients with Parkinson's disease and mild cognitive…
- Trial name
- NCT06801782
- Testing
- Experimental Cognitive training in Immersive Virtual Reality and Telemedicine approach, Active Comparator #1
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Glycemic Response
Effect of Oatmeal Varieties on Glycemic and Insulinemic Responses in Healthy Individuals
The objectives of this study are to compare the glycemic and insulinemic responses over 3 hours elicited by 3 oatmeal varieties compared to each other and to controls of ready to eat and hot cereals.
- Trial name
- NCT02616159
- Testing
- Oatmeal
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Schizophrenia
Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls
This study to find out whether a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity during sleep-especially sleep…
- Trial name
- ONSETS (NCT07680114)
- Testing
- TES-TI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Fatigue
Stimulation Sites and Fatigue Induced by Neuromuscular Electrical Stimulation in Healthy Individuals
Neuromuscular electrical stimulation (NMES) is a tool used in training protocols and in clinical practice to prevent or attenuate atrophy and improve the ability to produce muscle strength in different populations.
- Trial name
- NCT05605210
- Testing
- Electric stimulation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marco Aurélio Vaz, PhD
Patellofemoral Pain Syndrome
Comparison of Foot Posture, Plantar Pressure, and Postural Balance in Patellofemoral Pain Patients and Healthy Subjects
Patellofemoral pain syndrome (PFS) is a musculoskeletal problem characterized by pain felt in the front of the knee or behind the patella, commonly affecting individuals in adolescence or young adulthood, especially those engaged…
- Trial name
- NCT06314360
- Testing
- No intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Neuropathy;Peripheral, Thermal Hypesthesia
Effect of Topical Lidocaine on Warm and Cold Sensation in Healthy Individuals
The purpose of the present study is to systematically test the occurrence of paradoxical and illusory responses to cold and warm stimuli in healthy volunteers with artificial sensory loss.
- Trial name
- NCT04865185
- Testing
- Xylocaine spray 100mg/ml, Ethanol
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hemophilia A and B
Comparison of 30-Second Sit-to-Stand Test Performance Between Individuals With Hemophilia and Healthy Peers
Hemophilia is an inherited bleeding disorder characterized by recurrent musculoskeletal bleeding, particularly into joints, leading to impaired physical function and reduced functional performance.
- Trial name
- NCT07736976
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Healthy Individuals (Controls), PRIMARY HYPERTENSION PATIENT
The Effect of Motivational Interviewing on Knowledge, Self-Efficacy, and Treatment Adherence in Patients With Primary Hypertension Living in Semi-Rural Areas
This study is a single-center, single-blind, parallel-group randomized controlled trial designed to examine the impact of a Health Belief Model (HBM)-based motivational interviewing (MI) intervention on knowledge level…
- Trial name
- NCT07307924
- Testing
- Motivasyonel görüşme
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Hypercholesterolemia
LIP-01 in Hypercholesterolemia
The purpose of this study is to determine a safe and tolerable dose of LIP-01
- Trial name
- NCT00966225
- Testing
- LIP-01
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Afexa Life Sciences Inc
Cardiovascular Disease, Dyslipidemia
Effects of High Fruit, Vegetable, and Dairy Intake on Plasma Lipids and Blood Pressure in Healthy Individuals
The Dietary Approaches to Stop Hypertension (DASH) trial has been shown to reduce blood pressure and plasma total and LDL-cholesterol (C) compared to a Western diet, but shows no benefit on other blood lipid variables associated…
- Conditions
- Cardiovascular Disease, Dyslipidemia, Blood Pressure
- Trial name
- NCT01404897
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Hyperglycemia
The Effect of American Ginseng Root and Its Components on Glycemia in Healthy Individuals
To determine the effect of polysaccharides from American ginseng root on postprandial glycemia in healthy individuals.
- Trial name
- NCT00367926
- Testing
- American ginseng root / polysaccharides
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Risk Factor Modification Centre
Acute Kidney Failure With or Without:, MODS
Citrate Pharmacokinetics and Regional Citrate Anticoagulation in CRRT
1. To compare the differences of citrate pharmacokinetics in healthy individuals and critically ill patients as well as the influential factors. 2. To validate a pharmacokinetic model which has been established in a formal paper.
- Conditions
- Acute Kidney Failure With or Without:, MODS, Sepsis, Hepatic Insufficiency
- Trial name
- NCT00948558
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
No Condition, Healthy Individuals
Microneedle-based ISF Sampling Technique
This clinical investigation aims to evaluate the performance and safety of the PELSA system, a hollow microneedle-based medical device designed for the collection of dermal interstitial fluid (dISF) from human skin.
- Trial name
- MIST (NCT07882225)
- Testing
- PELSA System
- Where
- Germany
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ascilion AB
Healthy Volunteer
Comparison of a Torso-Based Derived 6-Lead Electrocardiogram (ECG) Device With Standard 12-Lead Electrocardiogram (ECG) in Healthy Volunteers
This study aims to compare electrocardiographic interval measurements obtained from a torso-placed six-lead electrocardiogram (ECG) device (torso-derived ECG; T-ECG) with those obtained from a standard 12-lead electrocardiogram…
- Trial name
- T-ECG (NCT07277374)
- Testing
- Torso-Based 6-Lead ECG Recording
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Healthy
Non-invasive Cerebellar Stimulation on Motor Learning
A crossover trial with healthy volunteers will be conducted. Six sessions will be performed once a week in a counterbalanced order and at least with seven days washout period to minimize carry-over effects.
- Trial name
- NCT02559518
- Testing
- tDCS, rTMS, pp-TMS assessment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Hand
Investigation of the Effect of Combined Motor Imagery and Activity Observation Therapy on Strengthening the Non-Dominant Hand in Healthy Individuals
Introduction: Motor Imagery (MI) and Action Observation (AO) are well-established cognitive training techniques that activate neural networks similar to those involved in actual motor execution.
- Trial name
- NCT07235449
- Testing
- Conservative treatment + Motor imagery program, Conservative treatment + Motor imagery and action observation program, Conservative treatment via strengthening exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Healthy Individuals (Clinicians)
Do Clinicians Want Recommendations?
The use of the best evidence available for decision-making is nowadays an undisputed goal in health care. However, this is not always achieved in the context of clinical practice.
- Trial name
- NCT02006017
- Testing
- Evidence summary alone plus a recommendation, Evidence summary alone
- Where
- Canada
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- McMaster University
Malaria
Experimental Vaccine for Malaria
This study will examine the safety and immune response of healthy adult volunteers to AMA1-C1, an experimental malaria vaccine developed by the NIAID.
- Trial name
- NCT00114010
- Testing
- AMA1/Alhydrogel
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)