Clinical trials: Healthy Individuals.
Healthy Individuals, Skin Electrical Potential
Understanding the Physiological Implications of Scanning Kelvin Probe Measurements
The purpose of this study is to evaluate the effects of skin thickness, skin moisture, and sweat gland density on Scanning Kelvin Probe measurements.
- Trial name
- NCT01545973
- Testing
- Skin Moistening, Skin Denuding
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy Aging
Frenkel Exercises in Geriatric Balance and Fall Prevention
Aging is a natural process starting from birth and progressing through childhood and adulthood, marked by physical and mental decline, including musculoskeletal, cognitive, and motor deterioration.
- Trial name
- NCT06990828
- Testing
- Frenkel Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Okan University
Romano-Ward Syndrome, Long QT Syndrome
Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients.
The objectives of the study are to investigate if KCNQ1 mutation in Romano-Ward long QT patients can be associated with changes in insulin regulation and with psychological features of compulsivity, impulsivity and behavioural…
- Conditions
- Romano-Ward Syndrome, Long QT Syndrome, Compulsive Behavior, Healthy Individuals
- Trial name
- PRIME (NCT04715256)
- Testing
- Cognitive assessment of obsessive-compulsive and impulsive behaviours, Genomic analysis, Glucoregulation assessment
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biotrial
Cognitive Impairment, Healthy Control
Prediction of MMSE Scores for Cognitive Impairment
This study aims to explore the potential of using machine learning (ML) algorithms to predict cognitive status, specifically MMSE scores, based on oral health and demographic data.
- Trial name
- NCT06611475
- Testing
- MMSE ≤26
- Where
- Sweden
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Healthy
Transcranial Focused Ultrasound (tFUS) Modulation of Reward Network
Aim: Evaluate whether sonicating the Nucleus Accumbens (NAc) with transcranial focused ultrasound modifies functional connectivity between the NAc and the prefrontal cortex (PFC).
- Trial name
- NCT05986019
- Testing
- transcranial focused ultrasound (tFUS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use, Unspecified
Effect of Different Foods Together With a Small Dose of Alcohol on Alcohol Levels in Healthy Subjects
Alcohol consumption is prevalent and frequently excessive and its use poses a major risk to both personal and public health. In the U.S., every month over 25% of adults and 40% of college students drink until their blood alcohol…
- Trial name
- NCT03867812
- Testing
- SOBAR, Control food, Full meal
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Zeno Functional Foods, LLC
Analgesia
RM1 Project 1 - tAN Naloxone
This two-visit, randomized, double-blind, sham-controlled trial, uses a novel naloxone blockade model in 136 individuals to determine whether the analgesic effects of a 30-minute transcutaneous auricular neurostimulation (tAN)…
- Trial name
- NCT05490134
- Testing
- Naloxone, Saline
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alzheimer's Disease (AD)
The Cognitive Effects of Lorazepam in Healthy Older Individuals With TOMM40 Variable-length Polymorphisms
The investigators' goal is to determine if certain tests of memory and attention, performed while sleepiness is induced by a single dose of lorazepam, can predict whether or not an individual is at risk for developing Alzheimer's…
- Trial name
- NCT01780519
- Testing
- lorazepam
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Influenza
Trial to Assess the Shedding,Immunogenicity, and Safety of FluMist Administered to Healthy Individuals 5-49 Years of Age
To describe the proportion of individuals 5-49 years of age who shed vaccine strain viruses. To describe the duration of shedding of vaccine viruses in individuals 5-49 years of age.
- Trial name
- NCT00192140
- Testing
- FluMist
- Where
- 11 sites in United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Healthy
Effect of B-GOS on the Wellbeing and Ageing in Healthy 52-65 Years Old Individuals
To investigate the potential of B-GOS to beneficially influence the wellbeing and ageing in healthy adults (52-65 years old). The study will consist of a 4 month randomised double blind parallel treatment period with either B-GOS…
- Trial name
- NCT02716350
- Testing
- B-GOS, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Clasado Limited
Healthy, Cigarette Smoking
A Study of Inhalation of 20,000 EU CCRE and Mucociliary Clearance (MCC) in Otherwise Healthy Individuals Who Are Current Cigarette Smokers
The purpose of this Phase 1 research study is to identify a dose of inhaled endotoxin that is safe (does not cause prolonged cough, shortness of breath or other problems), but causes changes in sputum cell samples that the…
- Trial name
- IRB 09-0259 (NCT00924768)
- Testing
- 20K EU CCRE
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Respiratory Muscles and Core Stabilization
Assessment of Trunk Muscle Endurance, Respiratory Functions and Respiratory Muscle Strength in Healthy Individuals
The diaphragm forms the upper segment of the core structure. At the same time, the diaphragm muscle acts as the first muscle in the inspiratory function.
- Trial name
- NCT03699566
- Testing
- Assessment of Respiratory Muscle Strength, Spirometer, Trunk Muscles Endurance Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Cognitive Functioning of Healthy Individuals, Hispanic
Norms and Validation for IntelliSpace Cognition Spanish Version
This study aims to validate and provide applicable norms for the United States (US) Spanish versions of the IntelliSpace Cognition (ISC) neuropsychological tests.
- Trial name
- NCT05210777
- Testing
- observation
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Healthy
Effects of Cocoa Procyanidins on Vascular Function
There is a question regarding the role of higher flavanol oligomers (procyanidins) and of intestinal flavanol metabolites i.e. valerolactones, in the context of flavanol intake-related vascular effects.
- Trial name
- NCT02728466
- Testing
- Flavanol and procyanidin supplement, Procyanidin-containing supplement, control supplement deprived of flavanols and procyanidins
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Medication Adherence, HIV Prevention
Single Dose Truvada Study
This study examines tenofovir (TFV) drug concentrations in adults one day after taking a single dose of Truvada® - a pill used to prevent and treat HIV infection.
- Trial name
- NCT03719053
- Testing
- Tenofovir
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Health People, Physical Activity
The Effect of Auricular Vagus Nerve Stimulation and Controlled Breathing Exercises on Performance and Autonomic Nervous System
There are many studies in the literature on transcutaneous vagus nerve stimulation (VNS) and controlled breathing exercises (CBE), but there are limited studies examining the effects of both interventions on performance and the…
- Conditions
- Health People, Physical Activity, Autonomic Nerveus System, Vagus Nerve Stimulations
- Trial name
- NCT06796101
- Testing
- Vagus Nerve Stimulation, Controlled breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Haemodynamic Rebound
Hemodynamic Repercussions of Noninvasive Ventilation
The noninvasive ventilation (NIV) is a method of ventilatory support that does not require artificial airway. Its application is associated with complex hemodynamic repercussions, therefore is important to identify them for…
- Trial name
- NCT02139631
- Testing
- Noninvasive ventilation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Cholestasis, Genetic Liver Disorder
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Cholestatic Disorders in Patients with Genetic Liver Disorders and Healthy Individuals
Purpose The primary goal is to study liver diseases with defects in bile excretion. Investigators aim to do this using a radioactive tracer that mimics human bile and can be visualized with a PET/CT scanner.
- Trial name
- NCT06610695
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Fibromyalgia
Effects of Breathing and Attention Training (BAT) on Pain Modulation
The hypersensitivity of fibromyalgia is associated with abnormal pain modulation within the CNS, but not with peripheral or central sensitization.
- Trial name
- NCT05773482
- Testing
- Breathing and Attention Training (BAT), Breathing Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Bariatric Surgery Candidate
Weight Regain After Bariatric Surgery and Web-Based Interactive Nurse Support Program: Mixed Methods Research
This study was planned to determine the effect of the web-based interactive nurse support program developed in line with the Health Promotion Model on healthy living behaviors and self-efficacy in individuals who gain weight…
- Trial name
- NCT04868279
- Testing
- Web-Based Interactive Nurse Support Program Based on Health Promotion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Cumhuriyet University