Clinical trials: Healthy Japanese
Thrombocytopenia
Identification of Donors of CD36-Deficient Platelets Among Japanese Individuals on the NIH Campus
Plasma histidine-rich glycoprotein (HRG) binds to platelets in the presence of zinc (1). This binding is totally blocked by a monoclonal antibody directed against platelet membrane CD36.
- Trial name
- NCT00015639
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy Male
Study of Aldafermin (NGM282) in Healthy Adult Male Japanese and Non-Japanese Subjects
This is an open-label study to assess safety, tolerability, and pharmacokinetics of Aldafermin (NGM282) in healthy adult male Japanese and non-Japanese subjects
- Trial name
- NCT04828265
- Testing
- Aldafermin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NGM Biopharmaceuticals, Inc
Diabetes, Healthy
Safety and Tolerability of Liraglutide in Healthy Japanese Volunteers
This trial is conducted in Japan. The aim of this trial is to assess the safety and tolerability of liraglutide in healthy Japanese male subjects.
- Trial name
- NCT01620476
- Testing
- liraglutide
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy Volunteers
Safety and Pharmacokinetics Study in Healthy Japanese Volunteers
The study consists of Part A, a randomized double-blind, single-ascending-dose study, and Part B, a randomized, double-blind, semi-sequential, escalating multiple-dose study, in healthy Japanese volunteers.
- Trial name
- NCT05032560
- Testing
- ABX464
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Abivax S.A.
H5N1 Influenza
H5N1 Vaccine Study in Japanese Adults
The purpose of this study is to obtain immunogenicity and safety data of two different dose levels of an H5N1 pandemic influenza vaccine in a healthy Japanese adult population aged 18 to 59 years.
- Trial name
- NCT01382329
- Testing
- H5N1 (pre-)pandemic influenza vaccine (whole virion, Vero Cell derived, inactivated)
- Where
- 3 sites in Japan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Healthy Volunteers
A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of TAK-123 After Intravenous Infusion in Japanese Healthy Adult Male Participants
The purpose of this study is to evaluate the PK, safety and tolerability of phenylacetate and benzoate after intravenous administration of TAK-123 in Japanese healthy adult male participants.
- Trial name
- NCT04155567
- Testing
- TAK-123
- Where
- Japan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy Volunteers
Multiple Dose Escalation Study of M201-A in Healthy Japanese Subjects
This Phase I is designed to evaluate the safety, tolerability and pharmacokinetics of multiple ascending doses of M201-A administered by multiple continuous intravenous injection in Healthy Japanese subjects.
- Trial name
- NCT04464681
- Testing
- M201-A Injection
- Where
- Japan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kitasato University
Japanese Encephalitis, Japanese Encephalitis Virus Disease
Study of a Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV™) Compared to CD.JEVAX™ in Toddlers
The purpose of this study is to compare Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV™) with Japanese encephalitis live attenuated vaccine (SA14 14 2 vaccine [CD.JEVAX™]) after a single dose vaccination to…
- Trial name
- NCT01396512
- Testing
- Live attenuated Japanese encephalitis chimeric virus vaccine, Japanese encephalitis live attenuated vaccine (SA14 14 2 vaccine)
- Where
- 6 sites in South Korea
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Healthy Japanese
A Study to Verify the Sleep-improving Effects of the Test Food Consumption
The goal of this clinical trial is to test in Japanese adults who feel sleepy when they wake up. The question it aims to answer are: •Does taking plasmalogens reduce sleepiness upon waking? Participants will be given the…
- Trial name
- NCT06907537
- Testing
- Food containing plasmalogen, Food without plasmalogen
- Where
- 2 sites in Japan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Orthomedico Inc.
Healthy Volunteers
A Study to Evaluate Safety and Tolerability After Single Oral Dosing of AZD1656 in Japanese Healthy Volunteers
The purpose of this study is to assess safety and tolerability of AZD1656 after single ascending oral doses in Japanese healthy male subjects
- Trial name
- NCT00741689
- Testing
- AZD1656
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
AZD Single Ascending Dose Study In Healthy Japanese Subjects
This is a single centre, open label, non-randomised study to access the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD3043 following a single dose administration to Japanese subjects.
- Trial name
- JSAD (NCT01028040)
- Testing
- AZD3043
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Pharmacokinetic Study of JNJ-56021927 When Taken Orally as Tablet Formulation in Healthy Male Japanese Participants
The purpose of the study is to assess the safety and Pharmacokinetic (PK) profile of JNJ-56021927 and its active metabolite JNJ-56142060 after single-dose administration of 60 milligram (mg), 120 mg, and 240 mg JNJ-56021927 as…
- Trial name
- NCT02835508
- Testing
- JNJ-56021927 60 Milligram, JNJ-56021927 120 Milligram, JNJ-56021927 240 Milligram
- Where
- Japan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutical K.K.
Healthy
A Study of LY3541860 in Healthy Japanese and Non-Japanese Participants
The main purpose of this study is to evaluate the safety and tolerability of LY3541860 in healthy Japanese and non-Japanese participants.
- Trial name
- NCT05042310
- Testing
- LY3541860
- Where
- Japan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy Volunteers
Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD of ONO-4685 in Japanese and Caucasian Healthy Adult Male Subjects
To investigate safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity in Japanese and Caucasian healthy adult male subjects when ONO-4685 is administered as a single-dose by intravenous infusion.
- Trial name
- NCT04079062
- Testing
- ONO-4685, KLH, KLH, ONO-4685
- Where
- Japan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Blood Pressure
Can Japanese Traditional Foods Lower Blood Pressure in Healthy Volunteers
The purpose of this study is to determine whether traditional japanese diet blood pressure in healthy volunteers.
- Trial name
- Horenso (NCT00928824)
- Testing
- traditional Japanese diet
- Where
- Japan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kyorin University
Healthy
A Study to Assess the Safety, Pharmacokinetics and Immunogenicity of CR8020 in Japanese Healthy Participants
The purpose of the study is to assess the safety, pharmacokinetics (what the body does to the drug) and immunogenicity (ability of a particular substance to provoke an immune response in the human body) of CR8020 in japanese…
- Trial name
- NCT02015533
- Testing
- CR8020
- Where
- Japan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutical K.K.
Healthy Volunteers
A Study to Evaluate Skin Irritation and Photo Irritation of JNJ 10229570-AAA on Intact Skin of Japanese Healthy Male Participants
The purpose of this study is to evaluate skin irritation and photo irritation of JNJ 10229570-AAA on intact skin of Japanese healthy male participants.
- Trial name
- NCT01494714
- Testing
- JNJ 10229570-AAA 1.2% cream, JNJ 10229570-AAA 2.4% cream, JNJ 10229570-AAA 3.6% cream
- Where
- 2 sites in Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutical K.K.
Healthy, Parkinson Disease
Lu AF82422 in Healthy Non-Japanese and Japanese Subjects and in Patients With Parkinson's Disease
The purpose of this study is to investigate the safety of a single dose of Lu AF82422, how well it is tolerated, how the drug effects the body and what the body does to the drug in healthy non-Japanese and Japanese subjects and…
- Trial name
- NCT03611569
- Testing
- Lu AF82422
- Where
- 4 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Volunteer
A Study to See How BIIB122 Works in the Human Body, and to Evaluate it's Safety, and Tolerability in Healthy Adult Japanese, Chinese, and Caucasian Participants
The study will be looking at an investigational drug, BIIB122, in healthy adult Japanese, Chinese, and Caucasian participants. The main goal of the study is to compare the drug level achieved in the body, between the different…
- Trial name
- NCT05229562
- Testing
- BIIB122
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Biogen
Healthy Volunteers
Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability and PK of ONO-2910 in Japanese and Caucasian Subjects
To investigate safety, tolerability and pharmacokinetics in Japanese and Caucasian subjects when ONO-2910 is administered as single and multiple doses orally.
- Trial name
- NCT04504760
- Testing
- ONO-2910
- Where
- Japan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ono Pharmaceutical Co., Ltd.