Clinical trials: Healthy Male
Healthy
A Study to Evaluate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of JNJ-404118413 in Healthy Male Patients
The purpose of the study is to evaluate the effect of JNJ-40411813 on rapid eye movement sleep and deep sleep; safety, tolerability and pharmacokinetics (what the body does to the study medication) of JNJ-40411813.
- Trial name
- NCT01951053
- Testing
- JNJ-40411813, Citalopram
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Renal Insufficiency
Pharmacokinetics of Certoparin in Subjects With Renal Insufficiency and Healthy Subjects
This study will assess the pharmacokinetics in subjects with severe renal insufficiency and healthy subjects.
- Trial name
- NCT01660295
- Testing
- Certoparin 3,000 IU Once Daily, Certoparin 3,000 IU Twice a Day, Certoparin 8,000 IU Once Daily
- Where
- Hungary
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Parkinson Disease
Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101
This is a Phase I, double-blind, randomised, two-part, single-ascending dose (Part 1) and multiple-ascending dose (Part 2) study of NM-101 in healthy males and healthy females of non-childbearing potential
- Trial name
- NCT05790382
- Testing
- NM-101
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Neuramedy Co. Ltd.
Healthy
Effects of Teduglutide on Cardiac Repolarisation and Conduction in Healthy Male and Female Volunteers
The primary objective of this trial is to investigate if teduglutide has an effect on cardiac repolarisation (QT, QTc interval).
- Trial name
- NCT01028924
- Testing
- Teduglutide
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Nycomed
Healthy
Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 1026706 in Healthy Male Subjects
The primary objective of this trial is to investigate the effect of multiple doses of itraconazole on the pharmacokinetics of BI 1026706 given as single dose.
- Trial name
- NCT02513446
- Testing
- BI 1026706, Itraconazole
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2
A Pharmacokinetic Study to Compare Co-administration of Repaglinide and Metformin HCl to Administration of Combination Preparation of Those Two Components
This is a phase-1, single center, open-label, randomized, single-dose, 2-way crossover study. The objective of the study is to compare the pharmacokinetic properties after co-administration of Repaglinide 2mg and Metformin…
- Trial name
- NCT01780051
- Testing
- Repaglinide/Metformin combination, Repaglinide, Metformin
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dalim BioTech Co., Ltd.
Diabetes Mellitus, Type 2
A Single-dose Phase 1 Study of DBPR108 in Healthy Male Subjects
The study is being performed to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) properties of single oral doses of DBPR108 in healthy male subjects.
- Trial name
- NCT01650324
- Testing
- DBPR108
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Healthy, Pharmacokinetics of Tamsulosin Hydrochloride
A Study to Compare How Tamsulosin is Absorbed to the Body After Administration of Two Types of Tamsulosin Formulation Under Fed and Fasted Conditions in Chinese Healthy Subjects
The purpose of this study is to investigate the relative bioavailability of two types of prolonged release formulation of tamsulosin hydrochloride in Chinese healthy subjects. The safety of tamsulosin formulation is also compared.
- Trial name
- NCT02138773
- Testing
- Tamsulosin formulation-A, Tamsulosin formulation-B
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma China, Inc.
Healthy Volunteers
First in Man Study of ALX-0651, a Nanobody Inhibiting CXCR4
The purpose of this first-in-man Phase I study is to determine whether the CXCR4-inhibitor ALX-0651 is safe and effective after single or multiple intravenous administrations to healthy male volunteers.
- Trial name
- NCT01374503
- Testing
- ALX-0651
- Where
- Netherlands
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ablynx, a Sanofi company
Healthy
Evaluate Different Extended-release (ER) Tablets/Capsules of AZD1305
To study the properties of different tablets/capsules of AZD1305 in healthy male volunteers.
- Trial name
- 2007-005765-38 (NCT00689403)
- Testing
- AZD1305
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Spot Reduction in Male Adults
Spot reduction, referring to local body fat reduction, pertains to subcutaneous adipose tissue utilization from specific body parts during exercise.
- Trial name
- NCT05794854
- Testing
- Abdominal aerobic endurance exercise, Control training intervention
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Molde University College
Reperfusion Injury, Vascular Complications
Trial to Investigate the Effect of Dapagliflozin on Ischemia Reperfusion Induced Endothelial Dysfunction
The aim of the study is to investigate the effect of dapagliflozin or placebo on acetylcholine (Ach)- or nitroglycerin (GTN)-induced vasodilation of the forearm resistance vasculature, as determined by FBF measurement before and…
- Trial name
- NCT05217654
- Testing
- Dapagliflozin 10mg
- Where
- Austria
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy
Metabolism and Pharmacokinetics of [14C]-BIBF 1120 in Healthy Male Volunteers
To assess the metabolic profile, to obtain the mass balance after oral administration, to determine the concentration of [14C]-radioactivity in blood cells, plasma, urine and faeces, to determine BIBF 1120 and BIBF 1202…
- Trial name
- NCT02182154
- Testing
- BIBF 1120 ES
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers
This randomized clinical trial studies the Family Caregiver Palliative Care Intervention in supporting caregivers of patients with stage II-IV gastrointestinal, gynecologic, urologic and lung cancers.
- Conditions
- Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter, Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT01846520
- Testing
- educational intervention, telephone-based intervention, quality-of-life assessment
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Healthy Male Subjects
Compare the Pharmacokinetics and Safety of BAT3306 Injection Versus KEYTRUDA® Administered in Healthy Male Subjects
to Compare the Pharmacokinetics and Safety of BAT3306 versus KEYTRUDA® Administered in Healthy Male Subjects
- Trial name
- NCT06111196
- Testing
- Recombinant Humanized Anti-PD-1 Monoclonal Antibody Solution for Injection, Pembrolizumab injection
- Where
- China
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Bio-Thera Solutions
Bioequivalence, Log-transformed AUCss and Cmax,ss Values for Saxagliptin and Metformin
Study in Healthy Subjects to Measure Amount of Drug in Blood After Dosing With Different Saxagliptin / Metformin Produc
Study in healthy subjects to measure amount of drug in blood after dosing with different saxagliptin / metformin products.
- Trial name
- NCT01441869
- Testing
- Onglyza (saxagliptin), Diabex, 5-mg saxagliptin/1000 mg metformin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Gastritis
A Study to Compare PK, PD and Safety of the AD-206 and Esomeprazole
A study to compare safety, pharmacokinetics and pharmacodynamics of AD-206 to Esomeprazole in healthy male volunteers.
- Trial name
- NCT03980756
- Testing
- AD-206 20mg, Esomeprazole 20mg, AD-206 40mg
- Where
- South Korea
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Healthy
AZD5985 Single Ascending Dose Study
The aims of this study are to assess the safety, tolerability and pharmacokinetics of single ascending oral doses of AZD5985 in healthy male subjects.
- Trial name
- NCT00967356
- Testing
- AZD5985
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Subjects
First-in-man Study of Single Ascending Dose of a New Drug for Neurological Disorders
The primary purpose of this first-in-man study is to investigate whether a new drug for neurological disorders is safe and well-tolerated when administered orally to healthy male adults
- Trial name
- NCT02719197
- Testing
- AC-083
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Healthy
Vasopressin Effects on Human Social Communication
This research is being done because we wish to understand how a chemical produced in the brain, vasopressin, effects emotional social communication processes.
- Trial name
- AVP (NCT01327027)
- Testing
- Vasopressin, Arginine, ADH
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Bowdoin College
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