Clinical trials: Healthy Male
Hyperlipidemia, Hypertension
To Evaluate the Safety and PK Characteristics in Healthy Volunteers-Livalozet
The purpose of this study is to compare pharmacokinetics between Pitavastatin and Valsartan co-administration and Livalo fixed combination drug in healthy male subjects.
- Trial name
- NCT01764178
- Testing
- Livalo fixed combination drug, Pitavastatin, Valsartan
- Where
- South Korea
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
Healthy
Bioequivalence of Telmisartan Film-coated Tablet Compared With the Conventional Telmisartan Tablet Following Oral Administration in Healthy Male Volunteers
Study to investigate the bioequivalence of the 40 mg telmisartan film-coated tablet vs. the conventional 40 mg telmisartan tablet
- Trial name
- NCT02263989
- Testing
- Telmisartan film coated tablet, Telmisartan conventional tablet
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Prolonged Labor, Healthy
Epidural Analgesia on Electrophysiological Function
Combined spinal-epidural analgesia (CSEA) is sometimes used for difficult births, but whether it contributes to postpartum pelvic muscle disorder is unclear.
- Conditions
- Prolonged Labor, Healthy, Pelvic Floor Disorders
- Trial name
- NCT02334150
- Testing
- CSEA (ropivocaine and sufentanil)
- Where
- China
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Nanjing Maternity and Child Health Care Hospital
Immunoglobulin A Nephropathy
A Study of MIL116 in Healthy Participants and Patients With IgA Nephropathy.
This is a Phase I/II study designed to evaluate the safety, tolerability, PK and PD of subcutaneous MIL116, an anti-APRIL monoclonal antibody, in healthy participants and patients with IgA Nephropathy.
- Trial name
- NCT07375758
- Testing
- MIL116
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Beijing Mabworks Biotech Co., Ltd.
Metabolic Syndrome
Investigation Into the Effects of Krill Oil vs. Fish Oil on Markers of Cardiovascular Disease
There is some evidence that dietary supplementation with fish oil has health benefits, especially in respect of some of the known risk factors for cardiovascular (heart) disease such as cardiac arrhythmia.
- Trial name
- NCT01705678
- Testing
- Krill oil, Fish oil
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Healthy
Safety and Tolerability of the First IV Dosing of SLV338 in Healthy Volunteers
This study will investigate the safety and tolerability of the first IV dosing of SLV338 in healthy volunteers.
- Trial name
- NCT00885989
- Testing
- SLV338
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Solvay Pharmaceuticals
Clinical Pharmacology
Study on the Safety of BAY 63-2521, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given as a Single Oral Dose of 1 mg Tablet in Participants With Renal Impairment and Healthy Participants Matched for Age-, Gender-, and Weight
BAY 63-2521 is intended to be used for a disease that affects the blood flow through the lungs. Renal impairment is a common condition in patients with this disease.
- Trial name
- NCT04364464
- Testing
- Riociguat (Adempas, BAY 63-2521)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
Relative Bioavailability of Two Fixed Dose Combination Tablets of Linagliptin/Pioglitazone Compared With Single Linagliptin and Pioglitazone Tablets Administered Together to Healthy Male and Female Subjects
Determination of the relative bioavailability of 2 different formulations of a 5 mg linagliptin (BI 1356)/45 mg pioglitazone fixed dose combination (FDC) tablet, formulation C5 and formulation C8, compared with the…
- Trial name
- NCT02183636
- Testing
- Linagliptin/pioglitazone, FDC formulation C5, Linagliptin/pioglitazone, FDC formulation C8, Linagliptin tablet
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Clear Cell Renal Cell Carcinoma (ccRCC)
A Study to Assess the Safety and Tolerability of BMS-986527 in Participants With Clear Cell Renal Cell Carcinoma (ccRCC)
The purpose of this study is to assess the safety and tolerability of BMS-986527 in participants with Clear Cell Renal Cell Carcinoma (ccRCC)
- Trial name
- NCT07848295
- Testing
- BMS-986527, Nivolumab, Cabozantinib
- Where
- 17 sites in United States, Belgium and 5 more
- Volunteers
- 112 people
- Sponsor
- Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Pharmacokinetics, Healthy Male Subjects
A Study to Find Out How YM150 is Absorbed Into and Eliminated From the Body in Healthy Male Subjects
The study aims to observe how YM150 was absorbed, distributed and excreted after dosing with a radio labeled drinking solution.
- Trial name
- NCT01657981
- Testing
- YM150
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Hepatic Impairment, Renal Impairment
A Study to Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment
This study will evaluate the pharmacokinetics (PK), safety, and tolerability of a single oral dose of zibotentan in patients with moderate hepatic and moderate renal impairment in comparison to a matched healthy control group.
- Trial name
- NCT05112419
- Testing
- Zibotentan
- Where
- Bulgaria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Male
A Study to Assess Safety, Tolerability, and Pharmacokinetics of Orally Administered GCC4401C in Healthy Volunteers
The purpose of this study is to evaluate the safety, tolerability and characterize the PK, PD f\profile.
- Trial name
- NCT01651234
- Testing
- GCC-4401, GCC-4401C
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Green Cross Corporation
Healthy
A Comparison of the Effects of Extended Release Tacrolimus (Advagraf®) vs. Immediate Release Tacrolimus (Prograf®) on Kidney Function in Healthy Male Volunteers
The purpose of the study is to evaluate the drug profiles (pharmacokinetics) and effects (pharmacodynamics) of Advagraf® and Prograf® on the kidneys.
- Trial name
- NCT01681134
- Testing
- Advagraf®, Prograf®
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Canada, Inc.
Pulmonary Disease, Chronic Obstructive
To Assess the Excretion Balance and Pharmacokinetics of a Single Oral Dose of [14C]GW856553 in Healthy Adult Males
This will be an open label study conducted at one site. Six healthy male subjects will be enrolled to ensure at least four fully evaluable subjects.
- Trial name
- NCT00599612
- Testing
- GW856553
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Tolerability of Asasantin in Healthy Female and Male Subjects
To investigate the occurrence of dipyridamole associated headaches in healthy subjects using a titration scheme or not
- Trial name
- NCT02269228
- Testing
- Asasantin ER
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Bioequivalence Study of Oxcarbazepine Oral Suspension 300 mg/5 mL Under Fasting Conditions
The study was conducted as an open label, balanced, randomized, two-treatment, two-period, two-sequence, single- dose, crossover bioavailability study comparing oxcarbazepine 300 mg/5mL oral suspension of OHM Laboratories (a…
- Trial name
- NCT00951600
- Testing
- oxcarbazepine 300 mg/5mL oral suspension
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Diabetes Mellitus, Type 2
A Study in Healthy Male Volunteers to Investigate Different Doses of a New Drug for the Treatment of Metabolic Diseases
The main purpose of the study is to see how safe SRT3025 (study drug) is when given at different doses. The study will also investigate how the study drug is taken up, metabolised (chemically broken down), distributed through the…
- Trial name
- NCT01340911
- Testing
- SRT3025
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Sirtris, a GSK Company
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Study on Mass Balance of [14C]HSK39297 in Healthy Chinese Adult Male Subjects
To evaluate the absorption, metabolism and excretion in healthy Chinese male subjects after a single oral dose of [14C]HSK39297
- Trial name
- NCT06852092
- Testing
- Carbon-14 labeled HSK39297
- Where
- China
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Healthy Male Volunteers
Drug-drug Interaction Between DWP14012 and Three Different Kinds of NSAIDs
drug-drug interaction between DWP14012 and three different kinds of NSAIDs
- Trial name
- NCT04490434
- Testing
- DWP14012, Celecoxib, Naproxen
- Where
- South Korea
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy
Study in Healthy Males to Assess Bioavailability of Single Fostamatinib With iv Micro Tracer Dose
Study in healthy males to assess bioavailability of single fostamatinib with iv micro tracer dose.
- Trial name
- NCT01598571
- Testing
- Fostamatinib
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
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