Clinical trials: Healthy Male Adults
Healthy Subjects, Pharmacokinetics of ASP015K
A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K
The objective of this study is to explore safety and tolerability of multiple oral doses of ASP015K in healthy volunteers.
- Conditions
- Healthy Subjects, Pharmacokinetics of ASP015K, Pharmacodynamics
- Trial name
- NCT01364974
- Testing
- ASP015K
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Low Back Pain
Clinical Trial to Evaluate the Food Effect on the Pharmacokinetics of Eperisone HCl SR Tablet 75mg
The purpose of this study is to evaluate the food effect on the pharmacokinetics of eperisone HCl SR tablet
- Trial name
- eperisone (NCT01885520)
- Testing
- fasting condition, fed condition
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- NVP Healthcare
Alzheimer's Disease
Safety Study of CTS21166 to Treat Alzheimer Disease
This study is the first human exposure for the drug candidate CTS21166 in healthy male volunteers
- Trial name
- CTS (NCT00621010)
- Testing
- CTS21166 (ZPQ-21166)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- CoMentis
Attention Deficit Hyperactivity Disorder
A Bioequivalence (BE) Study in Healthy Subjects
To demonstrate the bioequivalence of 12.5 milliliters (mL) of atomoxetine oral solution (4 milligrams per milliliter [mg/mL]) compared with 2 capsules of atomoxetine (25 mg per capsule) in healthy adult male Japanese subjects.
- Trial name
- NCT01177943
- Testing
- Atomoxetine
- Where
- Japan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy Volunteer
A Phase 1 Mass Balance Study of Varegacestat
This clinical study is designed to study the mass balance of a single dose of varegacestat in healthy male participants.
- Trial name
- NCT06845852
- Testing
- varegacestat
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Immunome, Inc.
Spasmodic Torticollis
An Electrophysiological Study Of E2014 In Healthy Adult Male Japanese And Caucasian Subjects
To evaluate inter-ethnic similarity in pharmacodynamics between Japanese and Caucasian healthy adult male subjects by comparing electrophysiological reactions after administering E2014 to extensor digitorum brevis muscle (EDB).
- Trial name
- NCT00280384
- Testing
- E2014 (Botulinum toxin type B)
- Where
- Japan
- Volunteers
- 48 people
- Sponsor
- Eisai Limited
Healthy Volunteers
Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults
The aim of this study is to understand how TAK-994 is processed by the body. This study will require participants to stay at the clinical research unit for 3 weeks to be monitored after receiving TAK-994.
- Trial name
- NCT04833049
- Testing
- TAK-994 Oral Tablet, [14C]TAK-994 Intravenous Infusion, [14C]TAK-994 Oral Suspension
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Takeda
EGFR Overexpression
A Randomized, Single Intravenous Dose, Parallel Phase I Clinical Study to Compare the Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX05 Vs. Erbitux® (Cetuximab) in Healthy Adult Male Chinese Subjects
This is a randomized, single intravenous dose, parallel study to compare the PK characteristics, safety, tolerability, and immunogenicity of HLX05 vs. Erbitux® (US-, EU-, and CN-sourced) in healthy adult male Chinese subjects.
- Trial name
- NCT06309043
- Testing
- recombinant anti-EGFR human/murine chimeric monoclonal antibody injection
- Where
- China
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Shanghai Henlius Biotech
ADME, Healthy
A Study to Evaluate the Mass Balance of 14C-Napabucasin in Healthy Adult Male Subjects
This is a Phase I, single-center, open-label, single-sequence, study evaluating the absorption, metabolism, and excretion of napabucasin in healthy adult male volunteers using a mixture 14C-radiolabeled and unlabeled material.
- Trial name
- NCT03525405
- Testing
- napabucasin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sumitomo Pharma America, Inc.
Health Volunteer
In Vivo Mass Balance Study of [14C]Hemay005
This study is a single-center, single-dose, non-randomized, open-label study to evaluate the in vivo mass balance of [14C]Hemay005. Six healthy male subjects are planned to be enrolled.
- Trial name
- NCT05468645
- Testing
- [14C]Hemay005
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Ganzhou Hemay Pharmaceutical Co., Ltd
Health Adult Subjects
A Study of JPH034 in Healthy Adult Participants
This study is designed to evaluate the safety, tolerability, and PK of JPH034 and identify side effects that occur in healthy participants between the ages of 18 and 50 years.
- Trial name
- NCT07534657
- Testing
- JPH034
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- J-Pharma Co., Ltd.
Healthy
A Study of Olanzapine After Intranasal and Intramuscular Administration
NRL-4, a nasal spray formulation of the atypical antipsychotic olanzapine is being developed by Neurelis Inc. for use as a rescue medication for acute episodes of agitation in schizophrenia, schizoaffective and bipolar I…
- Trial name
- NCT06600477
- Testing
- olanzapine
- Where
- Jordan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Neurelis, Inc.
Diabetic Foot
BE STUDY OF METFORMIN GSK 1000mg
A randomized, balanced, open label, crossover, two period, two treatment, two sequence, single dose, oral bioequivalence study under fasting condition.
- Trial name
- BA/BE 199/11 (NCT01710553)
- Testing
- Glucophage 1000mg, Metformin GSK 1000mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Clinical Pharmacology, Healthy Male Volunteer Study
Study to Evaluate Pharmacokinetics of Single Oral Doses of Formulated and Non-Formulated CC-122, and Food Effect Study
The study is being conducted to compare how long 2 oral formulations (a reference and a test formulation) of CC-122 stays in the body, and whether taking the test formulations with a high-fat meal affects the absorption of that…
- Trial name
- NCT02049528
- Testing
- CC-122
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Celgene
Healthy Participants
A Brain Imaging PET Study of [11C]-Lu AF88370 in Healthy Adult Male Participants
The main goals of the study are to assess uptake and distribution of Lu AF88370 in the brain when given at tracer levels (microdose) in healthy young men.
- Trial name
- NCT05320302
- Testing
- [11C]-Lu AF88370
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Volunteer
Comparison of DW-1021 and Separate Doses of Pelubi CR and Zytram CR Under Fasting Conditions
This is a Phase 1, randomized, open-label, single-dose, two-period, cross-over study to evaluate the pharmacokinetics (PK) of DW-1021, a fixed-dose combination tablet containing Pelubiprofen 45 mg and Tramadol 45.9 mg (as a…
- Trial name
- DW-1021 (NCT07032558)
- Testing
- DW-1021, Pelubi CR + Zytram CR
- Where
- 2 sites in Vietnam
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Haiphong University of Medicine and Pharmacy
Healthy Male Subjects
Study of RPT193 in Healthy Adult Male Subjects
Phase 1, open-label, absorption, metabolism, excretion, and mass balance study.
- Trial name
- NCT06087978
- Testing
- 14C RPT193
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- RAPT Therapeutics, Inc., a member of the GSK plc group of companies
Carbohydrate Metabolism, Hepatic Glycogen Storage
Effects of Dual-Source Carbohydrate Intake and Liver Glycogen Repletion After Overnight Fasting.
This study is looking at whether eating a breakfast which has two different sources of carbohydrates, glucose and fructose (found in foods like honey and fruits), can increase how much glycogen can be stored in the liver.
- Conditions
- Carbohydrate Metabolism, Hepatic Glycogen Storage, Healthy Adult Male
- Trial name
- NCT07476989
- Testing
- No breakfast, Breakfast (0% Fructose), Breakfast (50% fructose)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Healthy Volunteers - Male and Female
Acute Effects of a Single-Session Body Awareness Intervention on Cortical Activity and Interoceptive Accuracy
This study will examine the immediate (acute) effects of a single, 30-minute body awareness session on brain activity and interoceptive accuracy in healthy young adults aged 18-25.
- Trial name
- BBAT-EEG (NCT07736365)
- Testing
- Basic Body Awareness Therapy Intervention
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ertugrul Deniz Kose
Healthy Adult Male and Female Volunteers
Neurocognitive Effects of Extended-Release Methylphenidate in Healthy Adults
This study evaluated the effects of methylphenidate (MPH), a stimulant medication commonly used to treat attention deficit hyperactivity disorder (ADHD), in healthy adults without ADHD.
- Trial name
- NCT07742631
- Testing
- Methylphenidate Stimulant medication therapy
- Where
- South Africa
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa