Clinical trials: Healthy Male Adults
Pharmacokinetic
Phase 1 Pharmacokinetic Study of Minoxidil SL Tablets
This is a phase 1 randomized, double blind, crossover study examining the pharmacokinetic profile of two different doses of minoxidil sublingual tablets in healthy adult volunteers.
- Trial name
- NCT06679556
- Testing
- Strength A Sublingual Minoxidil, Strength B Sublingual Minoxidil
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Samson Clinical Operations Pty Ltd
Cyclists, Healthy Adult Male
The Effects of Beta-Alanine Supplementation on Mechanical Performance, Acid-Base Balance, Oxidative Stress, and Enzymatic Antioxidant Defence During Repeated Wingate Anaerobic Tests Under Normoxic and Hypoxic Conditions
Beta-alanine is a dietary supplement that increases skeletal muscle carnosine concentration and may enhance the muscle's ability to buffer hydrogen ions produced during high-intensity exercise.
- Trial name
- NCT07650162
- Testing
- beta-alanine, normoxic conditions, Normobaric hypoxic conditions (≈2500 m)
- Where
- Poland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Pharmacokinetics of ASP3325 in Non-elderly, Healthy Adult Japanese Male and Female, and Caucasian Male Subjects
A Single and Multiple Oral Dose Study and a Treatment Schedule-finding Study in Non-elderly, Healthy Subjects
The objectives of this study are to evaluate the safety and tolerability of a single and multiple oral dose of ASP3325 and to evaluate the effect of administration timing on the pharmacodynamics of ASP3325 orally administered…
- Trial name
- NCT02500953
- Testing
- ASP3325
- Where
- Japan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy Male Volunteers
Evaluation of Pharmacokinetic Interaction Between Micronized Fenofibrate and Pitavastatin
To evaluate pharmacokinetic drug interaction by comparing the steady-state pharmacokinetic characteristics of each arms after repeated administrating Lipilfen cap. 160mg and Livalo tab.
- Trial name
- NCT01767610
- Testing
- micronized fenofibrate 160mg, pitavastatin Ca 2mg, micronized fenofibrate 160mg plus pitavastatin Ca 2mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Healthy
Spot Reduction in Male Adults
Spot reduction, referring to local body fat reduction, pertains to subcutaneous adipose tissue utilization from specific body parts during exercise.
- Trial name
- NCT05794854
- Testing
- Abdominal aerobic endurance exercise, Control training intervention
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Molde University College
Healthy Adult Subjects
A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib
The primary objective of the study was to assess the effect of repeated oral doses of Rifampicin on the pharmacokinetic profile of a single dose of Famitinib.
- Trial name
- NCT04494659
- Testing
- Famitinib capsule, Rifampicin capsule
- Where
- China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Pharmacological Action
Exploratory Pharmacokinetic Study of Virgin Coconut Oil (VCO)
This is a balanced, open-label, single- and multiple-dose pharmacokinetic (PK) study of virgin coconut oil (VCO) among healthy Filipino male adults 18-45 years of age in Dasmariñas, Cavite.
- Trial name
- NCT06324370
- Testing
- Virgin Coconut Oil
- Where
- Philippines
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Food and Nutrition Research Institute, Philippines
Healthy Adult Subjects
A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers
The primary objective of this study is to evaluate the safety and tolerability of ONO-4053 across ascending single and multiple doses in healthy adult male and female subjects.
- Trial name
- NCT01379586
- Testing
- ONO-4053
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Overactive Bladder(OAB)
The Safety and PK Characteristics of the Co-administration of JLP-2002 and Comparator in Healthy Volunteers
A randomized, open-label, single-dose, replicate crossover study to compare the pharmacokinetics and safety in healthy adult volunteers following oral administration of JLP-2002
- Trial name
- NCT04914221
- Testing
- JLP-2002, Comparator
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Healthy
Megavec 400 mg (Imatinib Mesylate) in Healthy Adult Male Volunteers
The purpose of this Study is to Assess Safety and Pharmacokinetics of megavec 400 mg (Imatinib mesylate) under Fasted Conditions in Healthy Male Subjects.
- Trial name
- NCT01653314
- Testing
- Megavec, Glivec
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Solid Tumor
A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects
A Phase I, Open-label Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 Following a Single Oral Dose to China Healthy Male Subjects
- Trial name
- NCT05109832
- Testing
- 14C-IMP4297
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Impact Therapeutics, Inc.
Healthy
A Study to Evaluate the Effects of a Single and Multiple Oral Doses of GLPG3121 in Adult, Healthy, Male Subjects
This study is a first-in-human, Phase I, randomized, double-blind, placebo controlled, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of GLPG3121 after oral single ascending…
- Trial name
- NCT03899909
- Testing
- GLPG3121 SAD, GLPG3121 MAD
- Where
- Belgium
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Healthy Adults, Copeptin
Copeptin Changes After Food Intake
The purpose of this study is to determine whether copeptin levels are affected by food intake.
- Trial name
- CoMeal (NCT01772914)
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy
Effects of Acute Intake of Flavanols on Cerebral Oxygenation and Cognition in Young Male Adults
The study evaluates the impact of one acute dose of cocoa flavanols on brain oxygenation during a hypercapnia challenge, as well as impact on cognitive performance in young healthy males.
- Trial name
- NCT04374409
- Testing
- High-flavanol cocoa powder, Low-flavanol cocoa powder
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Pain, Acute
Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects
This study is designed to compare TRV130 to placebo and morphine to learn about its effects on pain relief and side effects.
- Trial name
- NCT02083315
- Testing
- TRV130 1.5 mg, TRV130 3 mg, TRV130 4.5 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Trevena Inc.
Clinical Pharmacology
Study to Compare the Effect of the Formulations (Orally Disintegrating Tablet and Film-coated Tablet) on the Bioequivalence of Drug Rivaroxaban (Xarelto) at Dose of 15 mg in Japanese Healthy Male Adult Subjects
Researchers in this study wanted to compare the effect of the formulation (orally disintegrating tablet and film-coated tablet) on the bioequivalence of drug Rivaroxaban (brand name: Xarelto) at dose of 15 mg in Japanese healthy…
- Trial name
- NCT04511637
- Testing
- Rivaroxaban (BAY 59-7939, Xarelto) in ODT form, Rivaroxaban (BAY 59-7939, Xarelto) in film-coated form
- Where
- 3 sites in Japan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
A Study to Evaluate the Bioavailability and Food Effect of JNJ-39439335 in Healthy Adult Male Volunteers
The purpose of this study is to evaluate the pharmacokinetics and relative bioavailability of a single dose of 3 capsule formulations of JNJ-39439335 in healthy adult male volunteers.
- Trial name
- NCT01454245
- Testing
- JNJ-39439335
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Rotavirus Gastroenteritis
A Study to Evaluate the Safety of Tetravalent Rotavirus Vaccine in Healthy Indian Adult Male Volunteers
This is a Phase I study to evaluate the safety and tolerability of the tetravalent rota virus vaccine in healthy Indian adult male volunteers administered a single dose of the vaccine at the highest possible viral concentration…
- Trial name
- NCT01091298
- Testing
- Live Attenuated Tetravalent (G1-G4) Bovine-Human Reassortant Rotavirus Vaccine (BRV-TV)
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shantha Biotechnics Limited
Undefined
Single Ascending-dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male Adult Subjects
Double-blind, placebo-controlled, First-in-Human, single ascending-dose study. Approximately 40 healthy adult male subjects will be given a single capsule of MYMD1 to determine its safety, how well it is tolerated, how the body…
- Trial name
- NCT04349761
- Testing
- MyMD1
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TNF Pharmaceuticals, Inc.
Healthy
Effectiveness of Hyperbaric Oxygen Therapy in Adults
The goal of this controlled, experimental study is to learn about the effects of 10 sessions of hyperbaric oxygen therapy on physical performance, vascular circulation, biochemical parameters, and composition of the intestinal…
- Trial name
- NCT06284603
- Testing
- Hyperbaric Oxygen Therapy - HBOT
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education