Clinical trials: Healthy Male Volunteer
Healthy Male Volunteers
AME Study of [14C]-PC14586 in Healthy Male Participants
This study will assess the PK and rates of elimination and mass balance of total radioactivity from [14C]-PC14586
- Trial name
- NCT05523687
- Testing
- [14C]-PC14586
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- PMV Pharmaceuticals, Inc
Healthy Adult Male
Evaluation of MTX-463 Administered Subcutaneously in Healthy Adult Males
A randomized, double-blind, placebo-controlled, study to assess the safety, tolerability, and PK of MTX-463 when administered via SC injection in healthy adult males.
- Trial name
- NCT07450521
- Testing
- MTX-463
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mediar Therapeutics
Healthy
Relative Bioavailability of BI 671800 HEA in Healthy Male Volunteers
To determine the relative bioavailability of single doses of 200 mg BI 671800 HEA (choline) administered as a delayed release (enteric coated) tablet; or via the EnterionTM capsule as solution to the jejunum, ascending or…
- Trial name
- NCT02222233
- Testing
- BI 671800 HEA delayed release (enteric coated) tablet, BI 671800 HEA solution, BI 671800 HEA particulate
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Chronic Kidney Disease
A Study to Evaluate the Safety and Efficacy of DDO-3055 in Healthy Volunteers and Patients With Chronic Kidney Disease
This is a randomized, double-blind, dose-escalating, placebo controlled, Phase I study to evaluate the safety, pharmacokinetics and pharmacodynamics of DDO-3055 in healthy volunteers and patients with chronic kidney disease.
- Trial name
- NCT03976115
- Testing
- DDO-3055
- Where
- China
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Chronic Pain
A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers
This is a randomised, placebo-controlled study of the safety and tolerability of single doses of MEDI0618 in healthy volunteer subjects.
- Trial name
- NCT04198558
- Testing
- MEDI0618
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Volunteer Male Subjects
A Comparative Bioavailability Study of Tamsulosin 0.4 mg Prolonged-release Tablets Versus the Reference Drug Omnic Ocas®, Tamsulosin Hydrochloride 0.4 mg, Prolonged-release Film-coated Tablets, in Healthy Adult Male Subjects, Under Fasting Conditions
The aim of this study is to evaluate the bioequivalence and safety of Tamsulosin hydrochloride 0.4 mg, prolonged-release tablets (Synthon Hispania SL, Spain), compared to Omnic Ocas®, Tamsulosin hydrochloride 0.4 mg…
- Trial name
- NCT07156916
- Testing
- Tamsulosin (0.4 mg/j)
- Where
- Armenia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Berlin-Chemie AG Menarini Group
Healthy
A Study of [14c]-Samidorphan (Also Known as ALKS 33) in Healthy, Male Volunteers
This study will determine the pharmacokinetics (PK) of [14c]-samidorphan in healthy male volunteers.
- Trial name
- NCT02504463
- Testing
- Samidorphan IV, [14c]-Samidorphan sublingual, [14c]-Samidorphan oral
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
Erectile Dysfunction, Benign Prostatic Hyperplasia
Evaluating a Pharmacokinetic Drug Interaction Between Tadalafil and Tamsulosin
We investigate the potential pharmacokinetic drug-drug interaction between Tadalafil and Tamsulosin in healthy male volunteers who receive Tadalafil alone, Tamsulosin alone, and both together in a 3 period repeatedly.
- Trial name
- NCT02239484
- Testing
- Tadalafil, Tamsulosin, Tadalafil + Tamsulosin
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Epstein-Barr Virus (EBV), Healthy Volunteers
A Longitudinal Study of Epstein-Barr Virus (EBV) Reactivation in Adults Aged 18 to 29 Years
This multi-center, prospective, longitudinal cohort study is designed to gather immunological and clinical data on EBV reactivation in EBV seropositive adults aged 18 to 29 years.
- Trial name
- NCT07536048
- Testing
- Investigational Procedure
- Where
- 2 sites in Australia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Urinary Tract Infections
Open Label Trial of Nissle 1917
Nissle 1917 is an E. coli based probiotic used in the Europe for close to 100 years to treat gastrointestinal disorders and infections.
- Trial name
- NCT02276508
- Testing
- E. coli Nissle 1917
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Elizabeth Lucas
Healthy
Clinical Trial to Characterize Pharmacokinetic-pharmacodynamic (PKPD) of Prasugrel 10 mg or 30 mg in Healthy Volunteers
An open label, parallel study to characterize the pharmacokinetics and pharmacodynamics of Prasugrel 30 mg or 60 mg in healthy male adult subjects
- Trial name
- PRAS-AM (NCT02075268)
- Testing
- prasugrel
- Where
- South Korea
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Diabetes Mellitus, Type II
A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/500mg in Healthy Male Volunteers
This study is a randomized, open-label, single dose, 2-way crossover study to compare the pharmacokinetic characteristics of CKD-395 0.25/500 mg in healthy male volunteers.
- Trial name
- NCT02685774
- Testing
- Duvie Tab. 0.5mg, Glucophage XR Tab. 500mg, CKD-395 0.25/500mg
- Where
- South Korea
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Tendon Injuries
GSK1278863 Effects on Eccentric Exercise-Induced Muscle Damage
As per non-clinical studies, prolyl hydroxylase inhibitor GSK1278863 can protect muscle from unaccustomed exercise induced muscle damage and enhance functional muscle repair.
- Trial name
- NCT02231190
- Testing
- GSK1278863
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteers
Assessment of Change in CYP3A Activity by Route of Administration Using Metabolic Markers in Healthy Male Volunteers
The study objective is to evaluate and validate of endogenous markers for the assessment of change in CYP3A activity by route of administration in Korean healthy subjects using metabolomics.
- Trial name
- CYP_IVPO (NCT03366974)
- Testing
- Midazolam, Clarithromycin, Grapefruit juice
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Healthy, Male
Crossover Study to Compare Pharmacokinetic Property of SYP-1512 Tab and Revlimid Cap in Healthy Male Volunteers
The purpose of this study is to evaluate the pharmacokinetics equivalence and safety by comparing pharmacokinetics characteristics between the SYP-1512 Tab and Revlimid cap (25mg) when administered a single-dose to healthy male…
- Trial name
- NCT03208218
- Testing
- SYP-1512, Revlimid cap
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Samyang Biopharmaceuticals Corporation
Hypercholesterolemia
Ascending Dose Study of the Safety and Tolerability of Alirocumab (SAR236553/REGN727) in Japanese Healthy Volunteers
Primary Objective: To assess the safety and tolerability of ascending single doses of subcutaneously (SC) administered alirocumab (SAR236553/REGN727) in Japanese healthy male subjects.
- Trial name
- NCT01448317
- Testing
- Alirocumab (Solution), Alirocumab (Lyophilized formulation)
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sanofi
Healthy
Pharmacokinetics and Safety Between "DWJ1421" and "DWC201903" in Healthy Male Volunteers
This is a randomized, open label, single dose, crossover study to compare the pharmacokinetics and safety between "DWJ1421" and "DWC201903" in healthy male volunteers.
- Trial name
- NCT04278391
- Testing
- DWJ1421, DWC201903
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy
Bioavailability of Different Pramipexole Slow-release Formulations Compared to Immediate-release Tablet in Healthy Male Volunteers
Study to compare the oral bioavailability of seven prototype slow-release formulations to immediate-release tablets
- Trial name
- NCT02261090
- Testing
- Formulation B: Pramipexole Slow release (SR) tablet, Formulation C: Pramipexole Slow release tablet, Formulation D: Pramipexole Slow release tablet
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteers
A Study to Evaluate the Metabolism and Excretion of [14C]-CC-92480 in Healthy Male Participants
This is a single-center, open-label study to be conducted in healthy adult male participants. This study is designed to characterize the biotransformation and excretion of [14C]-CC-92480 and to evaluate the safety and…
- Trial name
- NCT04560738
- Testing
- [14C]-CC-92480
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Celgene
Healthy Male Volunteers
Bioavailability of Pea Protein in Young and Old Volunteers
The aim of this study done in healthy, non-malnourished young and elderly subjects, is to measure the bioavailability of protein intake and the variation of metabolic markers following consumption of pea protein " NUTRALYS ® S85…
- Trial name
- NUTRALYS (NCT06381869)
- Testing
- Pea protein (NUTRALYS ® S85 plus) in water, Pea protein (NUTRALYS ® S85 plus) within meal, Whey protein in water
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Roquette Freres