Clinical trials: Healthy Male Volunteers
Healthy Volunteer
Comparative Bioavailability Study of Tablet and Granule Formulations of ADC189 and the Study of Ultra-high Dose
Part 1 of this study will compare the pharmacokinetic performance of tablet and granule formulations of ADC189 under fasted conditions in healthy volunteers. A randomized, two-period, two-treatment crossover design is used.
- Trial name
- NCT06428903
- Testing
- ADC189 tablet, ADC189 granules, ADC189 180mg
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Jiaxing AnDiCon Biotech Co.,Ltd
Kidney Failure, Chronic Therapy; Hemodialysis
A Single Ascending Dose Study of Soluble Ferric Pyrophosphate Administered Intravenously in Healthy Volunteers.
The purpose of this study is to determine the pharmacokinetics of fixed ascending doses of intravenously administered Soluble Ferric Pyrophosphate
- Trial name
- NCT01920854
- Testing
- soluble ferric pyrophosphate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rockwell Medical Technologies, Inc.
Healthy
Investigation of Pharmacokinetic Interaction Between Rosuvastatin and Olmesartan in Healthy Male Volunteers
This study investigates pharmacokinetics and drug-drug interaction between Rosuvastatin and Olmesartan in healthy male volunteers
- Trial name
- NCT01831479
- Testing
- Rosuvastatin, Olmesartan, Rosuvastatin and olmesartan
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Severance Hospital
Healthy Subjects
Pharmacokinetics and Bioavailability of Single Subcutaneous Doses of Methylnaltrexone Versus Intravenous Dose
This is an open-label, Phase I study. Study treatments will entail a four-way crossover among three single, ascending, subcutaneous doses and one intravenous dose of MNTX in six healthy normal male volunteers.
- Trial name
- NCT01367496
- Testing
- SC Methylnaltrexone (MNTX), IV Methylnaltrexone (MNTX)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Rheumatoid Arthritis
Comparison the Safety and Pharmacokinetic Characteristics of DWP422 25 mg With Those of ENBREL 25MG PFS INJ. After Subcutaneous Injection in Healthy Male Volunteers
The purpose of this study was to compare the safety and pharmacokinetic characteristics of DWP422 25 mg with those of ENBREL 25MG PFS INJ. after subcutaneous injection in healthy male volunteers.
- Trial name
- NCT01635686
- Testing
- DWP422 25mg, ENBREL 25MG PFS INJ.
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Growth Hormone Deficiency
Safety, Pharmacokinetics and Pharmacodynamics Study of HL-032 in Healthy Male Volunteers
The purpose of this study is to evaluate the safety, pharmacokinetics and pharmacodynamics of HL-032 after oral administration in healthy male volunteers.
- Trial name
- HL-032 (NCT01440686)
- Testing
- Somatropin
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- HanAll BioPharma Co., Ltd.
Healthy Volunteers
Food Effect on Pharmacokinetic Parameters of ABX464
The goal of this study is to determine the impact of the food on the absorption of the ABX464.
- Trial name
- NCT02731885
- Testing
- ABX464 Single dose, ABX464 Repeated dose
- Where
- Mauritius
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Abivax S.A.
Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2
A Study to Compare the Safety and Drug Levels in Blood When Using Various Forms of GSK189075 Given to Healthy Subjects
The purpose of this research study is to look at concentrations of GSK189075 in blood when different long and short acting forms of the drug are taken by mouth.
- Trial name
- NCT00559884
- Testing
- GSK189075 (Modified and immediate release formulations)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteer
AZD7325 Multiple Ascending Dose Study
This is a study to evaluate safety, tolerability, PK and PD effects of orally administered AZD7325 after single and repeated ascending doses.
- Trial name
- MAD (NCT00681915)
- Testing
- AZD7325
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Study to Assess the Metabolism, Excretion and Pharmacokinetics of [14C]AZD1981 in Healthy Male Volunteers
The purpose of the study is to characterize the absorption, distribution, metabolism and excretion (ADME) of a single oral dose of [14C]AZD1981
- Trial name
- ADME (NCT01058447)
- Testing
- AZD1981
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Hypertension
Bioequivalence Study (Candesartan 16 mg and Amlodipine 5 mg) - A
The purpose of this study is to compare the safety and pharmacokinetics of CKD-330 (fixed-dose combination of Candesartan 16 mg and Amlodipine 5 mg) with coadministration of the two separate drugs in healthy male volunteers.
- Trial name
- NCT02801526
- Testing
- CKD-330 16/5mg - A, Candesartan 16mg and Amlodipine 5mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Depressive Disorder and Anxiety Disorders
Emotional Processing in Healthy Volunteers in the Presence of an Investigational Anxiolytic
This will be a phase I, single centre, randomised, double blind, double-dummy, placebo controlled, parallel group single-dose study in healthy volunteers.
- Trial name
- NCT01424384
- Testing
- Citalopram, GSK424887, Plactebo To Match
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteers
A SAD and MAD Study of the Safety, Tolerability, and Pharmacokinetics of ATH-1105
The goal of this Phase 1 interventional study is to assess the safety, tolerability and pharmacokinetics of ATH-1105 in healthy male and female participants.
- Trial name
- NCT06432647
- Testing
- ATH-1105
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- LeonaBio
Healthy
Safety, Pharmacokinetic Study of PRIC in Healthy Adult Subjects
The purpose of this study is Safety, Pharmacokinetic Study of PRIC
- Trial name
- NCT03826485
- Testing
- PRIC, Pranlukast hydrate
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- SamA Pharmaceutical Co., Ltd
Healthy
Study to Assess the Pharmacokinetics of AZD6140 After Single Dose in Healthy Japanese Male Volunteers
The purpose of this study is to assess the pharmacokinetics of AZD6140 and its active metabolite, safety, tolerability of AZD6140 following single administration in healthy male Japanese volunteers.
- Trial name
- NCT01588626
- Testing
- AZD6140
- Where
- Japan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Male Participants
A Phase 1 Comparative Study to Evaluate Pharmacokinetics, Immunogenicity, Safety and Tolerability of Bmab3000 and Herceptin Hylecta® After a Single 600 mg SC Injection in Healthy Male Volunteers
This phase I study is to compare the pharmacokinetics (PK), immunogenicity, safety, and tolerability of Bmab3000 (test) and Herceptin Hylecta (reference) after a single subcutaneous (s.c.) dose in healthy male volunteers.
- Trial name
- NCT07299955
- Testing
- Bmab3000, Herceptin Hylecta®
- Where
- New Zealand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Biocon Biologics UK PLC
Healthy Volunteers
A Study to Compare the Pharmacokinetics of DP-R207 in Comparison to Each Component Administered Alone
The purpose of this study is to compare the pharmacokinetics of DP-R207 (Rosuvastatin 10mg and Ezetimibe 10mg fixed dose combinations) in comparison to each component administered alone in health male volunteers.
- Trial name
- NCT02730689
- Testing
- DP-R207, Rosuvastatin, Ezetimibe
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alvogen Korea
Healthy Volunteers
CC-223 and Ketoconazole Drug-Drug Interaction Study
This is a single-center open-label study to compare how CC-223 (the study drug being investigated) interacts with the drug ketoconazole.
- Trial name
- NCT01896323
- Testing
- CC-223, Ketoconazole
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Celgene
Depression, Depressive State
A Study to Compare the Pharmacokinetic Profiles of Etravil® Tablet 10mg and Etravil® Tablet 25mg
To evaluate the pharmacokinetics of single oral dose of Amitriptyline hydrochloride film-coated tablet 10mg \& 25mg
- Conditions
- Depression, Depressive State, Enuresis
- Trial name
- DWETR (NCT01367080)
- Testing
- DWETR10, DWETR25
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Healthy Volunteers
Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants
The purpose of this study is to determine ABA of TAK-906 following single oral (capsule) administration of 50 milligram (mg) of TAK-906 and single intravenous (IV) microtracer dose administration of 100 microgram (μg)…
- Trial name
- NCT04454918
- Testing
- TAK-906 Oral Capsule, [14C]-TAK-906 Intravenous Infusion, [14C]-TAK-906 Oral Solution
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Millennium Pharmaceuticals, Inc.
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