Clinical trials: Healthy Male Volunteers
Schizophrenia
Study Assessing SEP-363856 in Male and Female Volunteers With High or Low Schizotype Characteristics
This study is designed to evaluate the effects of a single dose of SEP-363856 in healthy male and female volunteers with high or low schizotype characteristics.
- Trial name
- NCT01972711
- Testing
- SEP-363856, Amisulpride
- Where
- 2 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Healthy Volunteers
Single Ascending Dose of ASP3772 Study in Japanese Healthy Male and Female Adults, and Single Ascending Dose Study of ASP3772 in Comparison With PPSV23 in Japanese Elderly Male and Female Subjects
The purpose of this study is to evaluate the safety and tolerability of 3 different dose levels of ASP3772 administered subcutaneously or intramuscularly to Japanese healthy adults 20 to 49 years of age.
- Trial name
- NCT04265911
- Testing
- ASP3772 (subcutaneous), ASP3772 (intramuscular), PPSV23 (subcutaneous)
- Where
- Japan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Affinivax, Inc.
Healthy, Pulmonary Disease, Chronic Obstructive
Relative Bioavailability of of Olodaterol and Ketoconazole
This clinical trial is intended to investigate a possible effect of the p-gp inhibitor ketoconazole on the bioavailability of olodaterol
- Trial name
- NCT01153711
- Testing
- BI 1744, Ketoconazole
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Doses of 40 mg Telmisartan/5 mg Amlodipine and 80 mg Telmisartan/5 mg Amlodipine in Healthy Male Volunteers
To investigate safety, tolerability, and pharmacokinetics of telmisartan and amlodipine following single administration of 40 mg telmisartan/5 mg amlodipine and 80 mg telmisartan/5 mg amlodipine, and subsequently, following…
- Trial name
- NCT02194309
- Testing
- Telmisartan low, Telmisartan high, amlodipine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Inflammatory Bowel Diseases
Phase I Clinical Trial in Healthy Male Volunteers
This is a Phase I Randomized,Double-Blind,Placebo-controlled Trial in Healthy Male Voluteers To Examine the Safety,Tolerability,and Pharmacokinetics of HMPL-011 After A Single Dose.
- Trial name
- NCT03860532
- Testing
- HMPL-011 tablets, HMPL-011 capsules
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hutchison Medipharma Limited
Normal Healthy Volunteers
Safety, Tolerability, and Pharmacokinetics of Oral BT-11 in Healthy Adult Male and Female Volunteers
Study type: Interventional Description of intervention(s) / exposure For single ascending dose, five dose target ranges of BT-11 (depending on body weight the doses in each cohort will be 5.9 - 7.7 mg/kg; 18.9 - 25.0 mg/kg; 44.3…
- Trial name
- NCT03860571
- Testing
- BT-11
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NImmune Biopharma
Neuropathic Pain
A Study to Investigate the Pharmacodynamic Effects of CT327 on Intra-dermal Nerve Growth Factor (NGF) and Evoked Pain Responses, in Healthy Male Volunteers
The primary objective of this study is to compare the effect of CT327 to placebo against experimental induced superficial, deep and hyperalgesic pain.
- Trial name
- NCT01243307
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Creabilis SA
Healthy Adult Participants, Diabetic Kidney Disease
Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease
This is a phase 1 randomized, double-blind, single ascending dose (SAD) and multiple ascending dose (MAD) study to assess the safety, tolerability, and Pharmacokinetics (PK) of single and multiple ascending doses of MTX-439…
- Trial name
- NCT07473323
- Testing
- MTX-439
- Where
- Australia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Mediar Therapeutics
Healthy
Study to Compare the Safety and Pharmacokinetic Characteristics of LBEC0101 25mg With Those of Enbrel®
To compare the pharmacokinetic characteristic of LBEC0101 25mg with active comparator, Enbrel® 25mg.
- Trial name
- NCT01725620
- Testing
- LBEC0101 (Etanercept 25mg), Enbrel (Etanercept 25mg)
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Kidney Stones, Kidney Calculi
Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased production of oxalate by the body, which would lead to increased urinary excretion of oxalate.
- Conditions
- Kidney Stones, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate
- Trial name
- NCT06989320
- Testing
- Low-oxalate diet and glycolate dosing, Oral glycolate dosing, Oral 13C- ascorbic acid dosing
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy Volunteers
Effects of 6-Week Vibration and Non-Vibration Foam Rolling
This study aims to compare the effects of 6-week vibration and non-vibration foam rolling on neuromuscular control and performance in male soccer players.
- Trial name
- NCT05988268
- Testing
- Vibration Foam Rolling, Non-Vibration Foam Rolling
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Cough
Repeat Doses of BAY1902607 in Healthy Males and Proof of Concept in Chronic Cough Patients
The primary objectives of this study: To investigate the safety and tolerability of ascending repeated oral doses of BAY1902607 in healthy subjects (Part 1).
- Trial name
- NCT03535168
- Testing
- BAY1902607, Midazolam
- Where
- 8 sites in Netherlands, United Kingdom
- Volunteers
- 59 people
- Sponsor
- Bayer
Healthy
Pharmacokinetics of HCP1305 and Co-administration of HCP0605, HGP0816 in Healthy Male Volunteers
To investigate the pharmacokinetics and safety/tolerability after administration of HCP1305 and co-administration of HCP0605, HGP0816 in healthy male volunteers
- Trial name
- NCT04039724
- Testing
- HCP0605 + HGP0816, HCP1305
- Where
- South Korea
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Amount of NKTR-118 in Blood, Variation in the Heart's Electrical Cycle
A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects
The purpose of this study is to evaluate the effects on QTc interval in healthy males when administered a single dose of NKTR-118 compared with placebo and moxifloxacin.
- Trial name
- NCT01325415
- Testing
- NKTR-118, moxifloxacin
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers
The primary objective of this study is to determine whether muscle atrophy induced by immobilization of the lower limb can be attenuated by BIIB023 in healthy male volunteers.
- Trial name
- NCT01943513
- Testing
- BIIB023
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biogen
Prostate Cancer
Carbon-11 Labeled Sarcosine in Prostate Cancer
Men with and without prostate cancer will have a PET/CT scan that measures the level of the amino acid sarcosine. PET is a scanning method that uses short lived radioactivity.
- Trial name
- NCT02462447
- Testing
- 11C-sarcosine, 11C-choline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Neuroscience
Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C] AZD2423 in Volunteers
Phase I study to evaluate the excretion of radioactivity, the metabolic profile, pharmacokinetics, safety and tolerability following a single oral administration of [14C]AZD2423 in healthy male volunteers aged 50 to 65 years…
- Trial name
- ADME (NCT01223014)
- Testing
- AZD2423
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fed
Galantamine Bioequivalence Study of Dr. Reddy's Under Fed Condition
Galantamine Hydrobromide Tablets, Bioequivalence study of Dr. Reddy's under Fed condition.
- Trial name
- NCT01372306
- Testing
- Reminyl
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Male Volunteers
The Effects of Daily Supplementation of Nutriose® on the Fecal Microbiota in Volunteers.
The effects of daily supplementation of the NUTRIOSE® on the fecal microbiota. The hypothesis of the study is that the NUTRIOSE® is able to modulate the intestinal microbiota in a positive way, compare to a placebo, in healthy…
- Trial name
- NUTRIBIOTE (NCT05105425)
- Testing
- NUTRIOSE®
- Where
- 2 sites in France
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Roquette Freres
Healthy
Study to Assess Safety, Tolerability and Pharmacokinetics of Single Rising Doses of BEA 2180 BR in Healthy Male Volunteers
Study to investigate safety, tolerability, and pharmacokinetics of single rising peroral doses of BEA 2180 BR
- Trial name
- NCT02254135
- Testing
- BEA 2180 BR - rising dose
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim