Clinical trials: Healthy Men
Alcohol Hangover
A Crossover Exploratory Study of NatureU Cheers Friends Curcumin on Acute Alcohol Hangover Symptoms
This was a single-center, open-label, exploratory crossover study evaluating acute hangover symptoms after use of NatureU Cheers Friends Curcumin compared with an active comparator product in healthy adult men.
- Trial name
- NUZY (NCT07585825)
- Testing
- NatureU Cheers Friends Curcumin, Herbsense Hangover Relief Tablet
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Healthy
This Study in Healthy Men Tests How Different Doses of BI 1265162 Are Taken up in the Body and How Well They Are Tolerated.
The primary objective of this trial is to investigate the safety and tolerability of BI 1265162 in healthy male subjects following inhalative administration of multiple rising doses.
- Trial name
- NCT03576144
- Testing
- BI 1265162
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Participants
Binding and Effects of Lu AG06466 in the Brain of Healthy Men
This study is being done to learn about the binding of Lu AG06466 and its major breakdown product (Lu AG06988) in the brain of healthy men having received multiple doses of Lu AG06466.
- Trial name
- NCT05219838
- Testing
- Lu AG06466
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Men
Study to Evaluate the Effects of Psyllium on Blood Glucose
This is an open label, single use, randomized, 4-period cross-over study. In each period, subjects will receive one of 4 test combinations.
- Trial name
- NCT00888602
- Testing
- 3.4 g psyllium, 6.8 g psyllium, Meal
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Healthy Volunteers
A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Abiraterone Following Administration of Abiraterone Acetate Tablets in Healthy Adult Men
The purpose of this study is to evaluate the pharmacokinetics, safety, and potential for drug-drug interactions when a strong inhibitor of CYP3A4 (ie, ketoconazole) is co-administered with abiraterone acetate in healthy adult men.
- Trial name
- NCT01588782
- Testing
- Period 1: Abiraterone, Period 2: Abiraterone/Ketoconazole
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy Men
A First Time in Man, Study to Assess the Safety of AZD8329 After Single Ascending Oral Doses
The primary objective for this study is to assess the safety and tolerability of AZD8329 when given as a single dose in increasing dose strength, and also to identify the highest tolerated dose for future studies.
- Trial name
- NCT00935662
- Testing
- AZD8329
- Where
- 2 sites in Sweden
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy, Psoriasis
This Study Tests How Healthy Men Tolerate Different Doses of BI 730357 and How the Metabolism of Midazolam is Affected by BI 730357
Phase Ib evaluation of the safety, tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) properties of Multiple Rising Dose (MRD) administration of BI 730357 to healthy volunteers for up to 28 days.
- Trial name
- NCT03279978
- Testing
- BI 730357, Midazolam
- Where
- Germany
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 894416 in the Blood
The main objective of this trial is to investigate the relative bioavailability of BI 894416 in plasma when given as oral single dose together with multiple oral doses of itraconazole (Test,T) as compared to when given alone as…
- Trial name
- NCT03722173
- Testing
- Itraconazole, BI 894416
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test Whether Rifampicin Influences the Amount of BI 425809 in the Blood
The primary objective of this trial is to investigate the relative bioavailability of a single dose of BI 425809 when given alone (Reference, B) compared with co-administration (Test, A) on the 7th day of a 10-day treatment with…
- Trial name
- NCT03082183
- Testing
- Rifampicin, BI 425809
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
This Study in Healthy Men Tests How Itraconazole Influences the Amount of BI 1015550 in the Blood
The primary objective of this trial is to investigate whether and to what extent co-administration of multiple doses of itraconazole affect single dose pharmacokinetics of BI1015550, i.e.
- Trial name
- NCT03403439
- Testing
- BI 1015550, itraconazole
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteer
Study to Evaluate the Concentration of Denosumab in Seminal Fluid in Healthy Men After a Single Subcutaneous Dose
This is a phase 1b, open-label, single dose study in healthy male subjects. Approximately 12 healthy male subjects will receive a subcutaneous injection of denosumab on Day 1.
- Trial name
- NCT01869686
- Testing
- Denosumab
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Amgen
Diabetes Mellitus, Type 2
Research Study Comparing Different Tablets With the Study Medicine Semaglutide in Healthy Men
This study looks at different tablets with a new study medicine called semaglutide. It is to treat diabetes. The aim of the study is to find out how much study medicine from 4 different tablets is taken up in the body.
- Trial name
- NCT03638778
- Testing
- Semaglutide 3 mg, Semaglutide 7 mg, Semaglutide B 3 mg
- Where
- Germany
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy Resistance-Trained Males
Comparison of Plant and Animal Proteins on Amino Acid Concentrations
The study purpose is to assess various protein blends, which differ in protein quality, and the impact on blood amino acid response in male subjects.
- Trial name
- NCT03673839
- Testing
- Animal Proteins (crossover), Plant-based protein blends type 1 (crossover), Plant-based protein blends type 2 (crossover)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Danone North America
Muscle Hypotrophy
Assessment of the Efficacy of Carnipure® AAS on Body Composition, Muscle Thickness, and Strength Adaptations in Healthy Men
This study is a 12-week randomized active control trial that is investigating the effects of Carnipure(R) AAS on muscle hypertrophy, body composition, and muscular strength adaptations in healthy men performing a resistance…
- Trial name
- NCT05681806
- Testing
- Carnipure AAS, Creatine Monohydrate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Secondary Hypogonadism
The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)
The study will determine the effects of three doses of Androxal(enclomiphene citrate)on morning testosterone versus AndroGel(approved topical treatment)in men with low testosterone (<350 ng/dL)after 6 weeks of continuous dosing.
- Trial name
- NCT01386606
- Testing
- Androxal (enclomiphene citrate), Testosterone
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Repros Therapeutics Inc.
Healthy
A Study in Healthy Men to Test How Well Different Doses of BI 1569912 Are Tolerated and How Food Influences the Amount of BI 1569912 in the Blood
SRD-Part: To investigate safety, tolerability, pharmacokinetics and pharmacodynamics following single rising doses (SRD) of BI 1569912 BA/FE-Part: To investigate (a) the relative bioavailability (BA) of BI 1569912 and (b) the…
- Trial name
- NCT04445090
- Testing
- BI 1569912
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2
A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Chinese Men
This study looks at how the new medicine called NNC0480-0389 works in the body of Chinese men when it is given at different doses together with a fixed dose of semaglutide.
- Trial name
- NCT05498610
- Testing
- NNC0480 0389, Semaglutide
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy
This Study in Healthy Men Tests How Different Doses of BI 1323495 Are Taken up in the Body and How Well They Are Tolerated.
The primary objective of this trial is to investigate the safety and tolerability of BI 1323495 in healthy male subjects following oral administration of single rising doses.
- Trial name
- NCT03588390
- Testing
- BI 1323495
- Where
- Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Signs and Symptoms, Digestive
Acute Gastrointestinal Tolerability Following a Single Serving of a Novel Dietary Fiber
The study will assess the gastrointestinal tolerability of a single serving of a novel dietary fiber at three different dose levels in generally healthy men and women.
- Trial name
- NCT02530762
- Testing
- Novel Fiber, Positive Fiber control, Negative Control
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cargill
Healthy
Study to Determine the Digestive and Physiological Effects of an Extract From Bran in Healthy Men and Women
The primary objective of this trial is to determine whether two doses of an extract from bran demonstrate a prebiotic effect on colonic bacteria (by modulating selected fecal microbial populations, particularly bifidobacteria).
- Trial name
- NCT01073969
- Testing
- wheat bran extract, control wheat bran extract
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kellogg Company