Clinical trials: Healthy Men
Atherosclerosis, Cardiovascular Disease
A Study Investigating Blood Concentrations Of Rosuvastatin When Co-administered With GW856553 In Healthy Men
This study is being conducted to provide initial safety and tolerability data as well as to provide PK data on potential interactions when GW856553 and rosuvastatin are co-administered in healthy male adults
- Trial name
- NCT00549653
- Testing
- GW856553
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
A Study in Healthy Men and Women to Find Out How Well Different Doses of BI 1291583 Are Tolerated
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 1291583 in healthy male and female subjects following oral administration of multiple rising doses over 4 weeks.
- Trial name
- NCT03868540
- Testing
- BI 1291583
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Normal Healthy Volunteers
Impact of Estradiol Addback
Repletion of testosterone (T) in older men drives Growth Hormone secretion after its aromatization to estradiol (E2) by potentiating endogenous GH drive.
- Trial name
- NCT01862835
- Testing
- Degarelix, Testosterone, Anastrozole
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy Volunteers
A Study to Test the Effects of Itraconazole and Carbamazepine on OPC-167832 in Healthy Men and Women
The purpose of this trial is to assess the potential for cytochrome P450 (CYP)-mediated drug-drug interactions (DDIs) with OPC-167832.
- Trial name
- NCT07542847
- Testing
- OPC-167832, Itraconazole, Carbamazepine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
HIV
Collection of Blood for Multiple Collaborative Studies
This study seeks to confidentially collect blood from HIV-positive individuals and HIV-negative controls to provide basic scientists with specimens for collaborative studies.
- Trial name
- NCT01336855
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
A Study in Healthy Men to Test How Bosentan Influences the Amount of Nerandomilast in the Blood
The main objective of this trial is to investigate the effect of bosentan, a moderate Cytochrome P450 (CYP) 3A inducer on the single dose pharmacokinetics of nerandomilast.
- Trial name
- NCT07081932
- Testing
- Nerandomilast, Bosentan
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test Whether Itraconazole Influences the Amount of BI 1584862 in the Blood
The main objective of this trial is to investigate the effect on the exposure of BI 1584862 in plasma when given as single dose together with multiple doses of itraconazole (Test, T) as compared to BI 1584862 when given alone as…
- Trial name
- NCT06041438
- Testing
- BI 1584862, Itraconazole
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Adults
Metabolic Availability of Lysine From White Maize
Our objective is to determine the metabolic availability of Lysine in white maize using the indicator amino acid oxidation (IAAO) technique in adult men.
- Trial name
- NCT02018575
- Testing
- Crystalline Lysine Amino Acid Mix, White corn meal porridge
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy Volunteers
Study to Evaluate and Compare the PK Profiles of Abaloparatide-SC and Abaloparatide-sMTS in a Cohort of Healthy Men and Healthy Women.
A study to evaluate and compare the PK profiles of abaloparatide-SC 80 μg and abaloparatide-sMTS 300 μg in a cohort of healthy men and to make a similar evaluation in a cohort of healthy women
- Trial name
- NCT04663464
- Testing
- abaloparatide-sMTS, abaloparatide-SC
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Radius Health, Inc.
Metabolic Health, Appetitive Behavior
Breakfast, Exercise and Metabolic Health in Healthy Men
This project aims to investigate the impact of acute bout of submaximal exercise under different pre-exercise dietary conditions (fasted state versus high carbohydrate breakfast versus high protein breakfast) on postprandial…
- Conditions
- Metabolic Health, Appetitive Behavior, Energy Balance
- Trial name
- NCT05291065
- Testing
- Fasted exercise, High protein breakfast exercise, High carbohydrate breakfast exercise
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Healthy
A Study in Healthy Men to Measure the Amount of BI 730357 in the Blood When Taken as a Tablet
To investigate the absolute oral bioavailability of BI 730357 administered as tablet compared with [C-14]BI 730357 BS administered as intravenous microtracer
- Trial name
- NCT03804671
- Testing
- BI 730357, BI 730357 mixed with [C-14] BI 730357 BS
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Young Men
Aronia Berry Consumption on Vascular Function
There is an increasing interest in the effects of various food derived polyphenols on vascular function. Arguably the most well-established vascular benefits are attributed to flavanols from cocoa beans and this has been…
- Trial name
- NCT03041961
- Testing
- Aronia full spectrum, Aronia extract
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- King's College London
Erectile Dysfunction
A Study of Semen Characteristics After 9 Months of Daily Tadalafil 20 mg
This is a multicenter, randomized, double-blind, placebo-controlled, fixed dose, parallel design study to evaluate effects on semen characteristics after 40 weeks of daily dosing with 20 mg tadalafil.
- Trial name
- NCT00382135
- Testing
- tadalafil
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Diabetes, Exercise Physiology
Elevated FFA and Skeletal Muscle Lipid Content
There is increasing evidence that skeletal muscle lipid content (IntraMyoCellular Lipid, IMCL) markedly increases the risk of metabolic complications, including insulin resistance and cardiovascular events.
- Trial name
- NCT01906333
- Testing
- Exercise, Glucose, Fasted
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy
Anti-exercise-fatigue Effects of Rice Protein RP-80NY in Men
The aim of this study is to investigate the anti-exercise-fatigue effects of rice protein RP-80NY in men
- Trial name
- NCT05560048
- Testing
- rice protein RP-80N
- Where
- Taiwan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Healthy
Study Evaluating MOA-728 Administered in Healthy Men
Absorption, distribution, metabolism, and excretion (ADME) study with 14C in healthy young men.
- Trial name
- NCT00427258
- Testing
- MOA-728
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Healthy
Assess Safety, Tolerability and PK of AZD3199 in Japanese
The primary objective of the study is to investigate the safety and tolerability of single and multiple once daily ascending doses of AZD3199 delivered as dry powder via the Turbuhaler inhaler in healthy male Japanese subjects by…
- Trial name
- NCT00772759
- Testing
- AZD3199 Turbuhaler®
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Wellness, Health
A Crossover Clinical Trial Investigating the Effects of Geranylgeraniol (GG) Supplementation on Testosterone Levels in Healthy Men and Women Over an 18-week Period
The primary purpose of this study is to investigate the effects of geranylgeraniol (GG) supplementation on testosterone levels in middle-aged (40 to 65 years) healthy men and women.
- Trial name
- NCT06747624
- Testing
- Geranylgeraniol 300 mg
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Designs for Health
Muscle Atrophy
Effects of Amino Acid Formulation on Healthy Men Undergoing Unilateral Knee Immobilization
This is a safety and tolerability study investigating the effect of an amino acid formulation in healthy volunteers during and after limb immobilization.
- Trial name
- NCT03267745
- Testing
- Amino Acid, Breg Brace single-leg immobilization
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Healthy
A Study in Healthy Men to Test How BI 1569912 is Processed in the Body
The main objectives of this trial are: To investigate basic pharmacokinetics of BI 1569912 and total radioactivity, including mass balance, excretion pathways and metabolism following oral administration of BI 1569912 (C-14) to…
- Trial name
- NCT06520553
- Testing
- BI 1569912 (C-14), BI 1569912 (C-13)
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim