Clinical trials: Healthy Men
Inflammation
Effects of Chronic Intake of Processed Foods on Circulating Inflammatory Markers in Healthy Men
This study aims to investigate the effects of diets enriched or depleted in foods at high risk of containing pro-inflammatory bacterial molecules, on markers of inflammation and cardiometabolic risk in healthy men.
- Trial name
- NCT02430064
- Testing
- Low PAMP diet
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Healthy
PROS-2 Dose Response Effects of Exogenous Testosterone on the Prostate
The investigators will conduct a three-month, randomized, placebo-controlled trial comparing the effects of increasing doses of androgen supplementation with Testosterone (T) gel on the prostate in healthy men who are treated…
- Trial name
- PROS-2 (NCT01327495)
- Testing
- Testosterone 1% gel 1.25 g, Testosterone 1% gel 2.5 g, Testosterone 1% gel 5.0 g
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Washington
Quality of Life
Whole Body Cryotherapy and Morphological and Rheological Indicators
The aim of the planned study was to evaluate the effect of repeated cryostimulation treatments on immunological, morphological, and biochemical indicators of the peripheral blood of healthy, young Men
- Trial name
- NCT04177563
- Testing
- whole body cryostimulation
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Healthy
A Study in Healthy Men to Compare Two Different Oral Formulations of BI 1810631 and to Test How Food or Rabeprazole Influence the Amount of BI 1810631 in the Blood
BI 1810631 trial formulation 1 (TF1) is currently used in clinical trials, but is planned to be replaced by another formulation (principle) in future clinical trials and on the market.
- Trial name
- NCT05380947
- Testing
- BI 1810631 - trial formulation 1 (TF1), BI 1810631 - new formulation (NF), Rabeprazole sodium
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healhty, Overweight or Obesity
Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM1812 Injection Following Single and Multiple Subcutaneous Administration in Normal to Overweight or Obese But Otherwise Healthy Men and Women
This is a Phase 1, single-center, double-blind, placebo-controlled, dose-escalation study. The study will evaluate the pharmacokinetics (PK), pharmacodynamic (PD), preliminary efficacy, safety and tolerability of BGM1812…
- Trial name
- NCT07224399
- Testing
- BGM1812
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BrightGene Bio-Medical Technology Co., Ltd.
Clinical Trials, Phase I as Topic
BAY 1902607: Single Dose Escalation, Safety and Tolerability, Pharmacokinetics, Bioavailability, Food Effect
This study is a first-in-man study that will investigate the safety, tolerability and pharmacokinetics of ascending single doses of BAY1902607 using a placebo controlled, randomized, single center design.
- Trial name
- NCT03212586
- Testing
- BAY1902607
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bayer
Cytomegalovirus Infections
Safety and Immunogenicity of the Human Cytomegalovirus (CMV) Vaccine (V160) in Healthy Japanese Men (V160-003)
The purpose of the study is to assess the safety and tolerability of a 3-dose regimen of V160 administered by intramuscular (IM) injection in healthy Japanese male participants by cytomegalovirus (CMV) serostatus.
- Trial name
- NCT03840174
- Testing
- V160
- Where
- Japan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Muscular Atrophy
Two Weeks of Reduced Activity and Skeletal Muscle Health in Older Men
Muscle size declines at around 0.5-1% per year after 50 years of age, with muscle strength declining up to twice as fast as muscle size.
- Trial name
- NCT02495727
- Testing
- Step-reduction, Pre-training, Exercise snacking
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Bath
Healthy Subjects
Metabolic Responses to Spermidine Supplementation.
Spermidine is naturally present in cells, organs, circulating cardiovascular system, and as part of our normal dietary intake. Studies suggest Spermidine is involved in antioxidation, autophagy, apoptosis, and immune regulation.
- Trial name
- NCT05459961
- Testing
- oral spermidine
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chrysea Labs Lda
Healthy
SSRI Effects on Semen Parameters in Men
According to the National Institute of Mental Health, depressive disorders afflict over six million U.S. men annually. Most cases of moderate or severe depression are treated with antidepressants, including monoamine oxidase…
- Trial name
- NCT00385762
- Testing
- paroxetine
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Healthy Men, Male Contraception
Phase 1 Study of Dimethandrolone Undecanoate in Healthy Men
The long term objective is to develop a new male hormone Dimethandrolone Undecanoate (DMAU) as a male hormonal contraceptive. The study has two parts.
- Trial name
- DMAUPhase1 (NCT01382069)
- Testing
- Dimethandrolone Undecanoate
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Hypophosphatemia
FGF-23 Suppressibility by Calcitonin
Introduction: Based on our experience with calcitonin as an FGF-23 suppressive agent in a patient with an FGF-23 producing tumor we hypothesize that calcitonin may be a physiologically important regulator of FGF-23 production and…
- Trial name
- NCT00688077
- Testing
- Calcitonin
- Where
- Netherlands
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Erectile Dysfunction
The Impact of a Plant-based Meat Meal Versus an Animal Meat Meal on Erectile Function in Healthy Men.
The goal of this study is to determine whether erectile function is differentially impacted by a single plant-based meat meal versus a single animal meat meal in healthy men with normal erectile function.
- Trial name
- ERECTION 2 (NCT06273592)
- Testing
- Animal-based meal, Plant-based meat meal
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Healthy Volunteer
Study to Evaluate the Concentration of Denosumab in Seminal Fluid in Healthy Men After a Single Subcutaneous Dose
This is a phase 1b, open-label, single dose study in healthy male subjects. Approximately 12 healthy male subjects will receive a subcutaneous injection of denosumab on Day 1.
- Trial name
- NCT01869686
- Testing
- Denosumab
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Amgen
Healthy
Evaluate the Pharmacokinetics and Gonadotropin Suppression of Nestorone®-Testosterone (NES/T) Combination Gel in Men
This is a prospective, randomized, double-blinded, two-center trial to evaluate the gonadotropin suppressive activity of transdermal treatment with a combined NES/T gel, or T gel alone, for 28 days.
- Trial name
- NCT02432261
- Testing
- Nestorone® /testosterone gel, Testosterone only gel
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kimberly Myer
Cytochrome P450 Interaction
Study Evaluating the Effect of Multiple Doses of Itraconazole on the Drug Lu AF35700 in Healthy Young Men and Women
This study will investigate the effect of multiple doses of the strong P450 enzyme inhibitor itraconazole on the pharmacokinetics of Lu AF35700 in healthy subjects.
- Trial name
- NCT03103646
- Testing
- Lu AF35700, Itraconazole (200 mg), Itraconazole (300 mg)
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Volunteers
Effect of Calcium 500 mg and Vitamin D3 1000 IU Chewable Tablet on Intestinal Calcium Absorption
The purpose of this study is to demonstrate that the intestinal absorption of calcium from a novel calcium carbonate-vitamin D3 chewable tablet formulation (calcium 500 milligrams (mg) and vitamin D3 1000 International Units…
- Trial name
- NCT02338713
- Testing
- Calcichew D3, Noncarbonated Water
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy Men
Study, Evaluating Pharmacokinetics, Immunogenicity and Safety Profiles of Pertuzumab Compared to Perjeta® in Healthy Man
PERT-1/12102020 is a double-blind randomized single-center clinical trial comparing pharmacokinetics, immunogenicity and safety profiles of Pertuzumab (manufactured by Mabscale, LLC) compared to Perjeta® in healthy men.
- Trial name
- NCT05825781
- Testing
- Pertuzumab, Perjeta®
- Where
- Russia
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Mabscale, LLC
Healthy
the Regulation of Phosphorus Homeostasis by Dietary Phosphorus Intake in Normal Men
The investigators have conducted the study about the effects of normal diet and low-phosphorus diet on phosphorus homeostasis in healthy subjects, now this study is designed to explore further about the effect of high-phosphorus…
- Trial name
- NCT03208075
- Testing
- normal diet, low-phosphorus diet, high-phosphorus diet
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Bone Resorption, Osteoporosis
The Effect of Protein Supplementation on Bone Health in Healthy Older Men and Women
Women and men consuming a low protein diet may be at risk for bone loss. The purpose of this study is to determine whether a daily protein supplement will improve bone health among healthy older adults.
- Trial name
- NCT00421408
- Testing
- Whey protein supplement
- Where
- 2 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Yale University