Clinical trials: Healthy Men
Healthy
A Study in Healthy Men and Women to Test Which Effects Donepezil and BI 425809 Have on Each Other
The main objective of Part 1of this trial is to investigate the effect of co-administration of multiple doses of donepezil on the single-dose pharmacokinetics of BI 425809 in healthy subjects.
- Trial name
- NCT03905096
- Testing
- BI 425809, Donepezil
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Men
A First Time in Man, Study to Assess the Safety of AZD8329 After Single Ascending Oral Doses
The primary objective for this study is to assess the safety and tolerability of AZD8329 when given as a single dose in increasing dose strength, and also to identify the highest tolerated dose for future studies.
- Trial name
- NCT00935662
- Testing
- AZD8329
- Where
- 2 sites in Sweden
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Muscle Atrophy
Effects of Amino Acid Formulation on Healthy Men Undergoing Unilateral Knee Immobilization
This is a safety and tolerability study investigating the effect of an amino acid formulation in healthy volunteers during and after limb immobilization.
- Trial name
- NCT03267745
- Testing
- Amino Acid, Breg Brace single-leg immobilization
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Healthy
Single Ascending Dose Study of Lu AF76432 in Healthy Young Men
The purpose of this study is to investigate safety, tolerability and pharmacokinetics of the drug Lu AF76432 given as single oral ascending doses to healthy young men
- Trial name
- NCT03531229
- Testing
- Lu AF76432
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Covid-19 Vaccine
Oxidative Stress Parameters, Trace Element and Quality of Life in Men Before and After Covid-19 Vaccines
With the rapid spread of COVID-19 (SARS-CoV-2) disease all over the world and the announcement of a pandemic, research on many different drug approaches has begun and these researches continue today.
- Trial name
- NCT04751695
- Testing
- CoronoVac Vaccine
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Healthy
Cognitive Effects of Citicoline on Attention in Healthy Mean and Women
The objective of this trial is to determine the effects of citicoline on cognitive performance for attention in healrhy Men and Women compared to a placebo.
- Trial name
- NCT04967157
- Testing
- Citicoline supplement
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Kirin Holdings Company, Limited
Pharmacokinetics
Pharmacokinetic Profile of N-Acetyl Cysteine
The study compares three different formulations containing N-Acetyl Cysteine, with regards to acute absorption over a 24-hour period, following single ingestion.
- Trial name
- NCT06252519
- Testing
- NAC, Neuro-NAC, Neuro-NAC XS
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Gastroenterology
Investigating the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Olamkicept in Healthy Japanese Persons
Interleukin (IL)-6 is a cytokine produced in response to infection and tissue damage. IL-6 is believed to act as a key mediator in chronic inflammation and autoimmune diseases such as inflammatory bowel diseases.
- Trial name
- NCT06515834
- Testing
- FE 999301
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Healthy
A Study in Healthy Men to Test How Different Doses of BI 3000202 Are Tolerated and How Food Influences the Amount of BI 3000202 in the Blood
The single rising dose (SRD) part of the trial investigates safety, tolerability, and pharmacokinetics of BI 3000202. The food effect (FE) part is conducted to assess the effect of food on the relative bioavailability of the BI…
- Trial name
- NCT05945888
- Testing
- BI 3000202
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study to Test How Food Influences the Amount of BI 1323495 in the Blood of Healthy Men
The main objective of this trial is to assess the effect of food on the pharmacokinetics of an oral tablet formulation of BI 1323495 by investigating the relative bioavailability following single dose administration under fed and…
- Trial name
- NCT03802331
- Testing
- BI 1323495,
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test How BI 474121 is Tolerated
Safety, tolerability, and pharmacokinetics of BI 474121 will be assessed in healthy Japanese male using single rising oral doses in order to provide the basis for an ongoing clinical development of BI 474121 for the treatment of…
- Trial name
- NCT04964453
- Testing
- BI 474121
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Cold Exposure, Body Temperature Regulation
Hand Cooling With Ice Packs in Healthy Young Men
This randomized, parallel-group study looked at how a standard 15-minute ice pack applied to the back of the hand affects skin temperature and how cold and comfortable the hand feels, compared with a room-temperature water pack.
- Conditions
- Cold Exposure, Body Temperature Regulation, Thermal Comfort Perception
- Trial name
- ICEHAND (NCT07254182)
- Testing
- Ice Pack (Localized Cryotherapy), Thermoneutral Water Pack (Control)
- Where
- Poland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Bioequivalency
Bioequivalence Study Between Two Oral Formulations of Ibuprofen 800 mg Tablets Under Fed Conditions
Compare the rate and extent of absorption of two oral formulations of Ibuprofen 800 mg Tablets, administered as a 1 x 800 mg tablet, under fed conditions.
- Trial name
- NCT00803946
- Testing
- Ibuprofen Tablets, 800 mg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Perrigo Company
Hyperglycemia, Hyperlipidemia
Healthy Volunteers Study of the Effects of Olanzapine and Ziprasidone
Primary Aim: To test the acute effects of olanzapine or ziprasidone administration, in comparison to placebo, on insulin sensitivity in antipsychotic-naïve healthy young men, measured as whole-body dextrose infusion rates…
- Trial name
- NCT00910988
- Testing
- Olanzapine, Ziprasidone
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Healthy
A Study in Healthy Men to Find Out How BI 1015550 is Taken up and Handled by the Body
The main objective of this trial is to investigate the basic pharmacokinetics of BI 1015550 and its metabolite BI 764333 (M480), [14C]-radioactivity, including mass balance, excretion pathways and metabolism following a single…
- Trial name
- NCT04771286
- Testing
- BI 1015550 (C-14)
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteer
Investigate the Safety Tolerability and Pharmacokinetics of Multiple Doses of AZD1236
The purpose of this study is to investigate the safety, tolerability and pharmacokinetics of multiple ascending oral doses of AZD1236 given to healthy young subjects for 13 days and to evaluate the single-dose relative…
- Trial name
- NCT00767052
- Testing
- AZD1236
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Men
Metabolic Availability of Lysine From Millet in Adult Men
Protein is the key determinant of growth and bodily functions. The quality of food proteins depend on their amino acid content and the amount of amino acids used by the body to make proteins.
- Trial name
- NCT03339167
- Testing
- Metabolic availability of lysine in millet
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Fasting
Alteration in Body Composition and Metabolic Profile During Ramadan Fasting in Healthy Men
One of religious duties for all healthy adult Muslims is fasting during Ramadan, the ninth month of Islamic lunar calendar. In this month, Ramadan observance fasted (no food and drink) from dawn to dusk.
- Trial name
- NCT03098381
- Volunteers
- 27 people
- Sponsor
- Chulalongkorn University
Healthy Young Men, Healthy Young Women
Characterization of the Plasma Metallomic Profile to Acute Exercise in Healthy Men and Women (METALEXO)
Among the various trace elements playing a key role in physical performance, iron is probably one of the most studied in the last 30 years.
- Trial name
- METALEXO (NCT05718752)
- Testing
- Maximal incremental exercise test, 30-min submaximal exercise test
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Effect of Selenium on Oxidative Stress in Healthy Men
Influence of Selenium on Prostate Cancer Related Biomarkers
Penn State Milton S. Hershey Medical Center researchers are trying to compare the effects of two different forms of selenium (selenium yeast and selenomethionine) on blood selenium levels and biomarkers of oxidative stress as…
- Trial name
- NCT01112449
- Testing
- selenomethionine, low dose selenized-yeast, high dose selenized-yeast
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center