Clinical trials: Healthy Men
Healthy Subjects
To Study the Effect of Aprocitentan on the Electrical Activity of the Heart in Healthy Men and Women
To demonstrate that multiple-dose administration of oral therapeutic and supratherapeutic doses of aprocitentan do not have a clinically relevant effect on the QT interval.
- Trial name
- NCT04281342
- Testing
- Aprocitentan 25 mg, Aprocitentan 100 mg, Moxifloxacin control to establish assay sensitivity
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Febrile Illness Acute, Inflammation
The Effects of Amino Acid Supplement During Acute Inflammation.
The purpose of the study is to investigate the metabolic effects during acute inflammation with and without the nutritional supplement of amino acids. E.
- Conditions
- Febrile Illness Acute, Inflammation, Metabolic Diseases
- Trial name
- NCT01705782
- Testing
- E. coli endotoxin, US standard
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Infertility, Male
The Effect of Supplementation With Fish Oil (EPAX EVOLVE 05) on Sperm Quality
The study will enrol men that have a poor sperm quality. They will take either a placebo or fish oil capsule (2 per day) for 3 months.
- Trial name
- NCT06950203
- Testing
- Very Long Chain Polyunsaturated Fatty Acids, Comparator arm (DHA)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Epax Norway AS
Sarcopenia, Muscle Atrophy
Multidisciplinary Research Into the Effects of Resistance Exercise and Whey Protein Supplementation in Healthy Older Men
The aim of this randomised, double-blind, placebo-controlled, parallel groups trial is to investigate the effects of 12 weeks resistance exercise and whey protein supplementation on energy metabolism, markers of appetite…
- Trial name
- NCT03299972
- Testing
- Whey Protein, Control, Resistance Exercise
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Coventry University
Quality of Life
Impact of Different Carbohydrate Feedings on a Hydrogen Breath Curve and Self-reported Gastrointestinal Complaints
GI distress is widely prevalent among athletes, ranging from 30 to 90% in recreationally and professionally active athletes. As the recipient of nutrients, the gastrointestinal (GI) tract plays an important role in athleticism.
- Trial name
- NCT06648967
- Testing
- Supplementation with a multi-ingredient whey supplement
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Contraception
Hormonal Contraception in Healthy Young Men (P42306)(COMPLETED)(P06057)
Male volunteers receive a new hormonal contraceptive consisting of an implant releasing a hormone and hormone injections in order to investigate the suppressive effect on sperm production and reversibility of sperm production…
- Trial name
- NCT00403793
- Testing
- etonogestrel with testosterone undecanoate
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Healthy Men and Subjects With Ulcerative Colitis
A Phase 1 Study of KHK4083 in Healthy Volunteers and Subjects With Ulcerative Colitis
The objectives of this study are to evaluate the safety and tolerability of a single intravenous (IV) or subcutaneous (SC) dose of KHK4083 in Japanese or White healthy men in a placebo-controlled, single-blind comparative study…
- Trial name
- NCT02985593
- Testing
- KHK4083
- Where
- Japan
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Healthy, Glucose Metabolism
Protein Concentrations in Yogurt and Satiety, Food Intake and Glycemia in Healthy Men
This study compared the effects of dairy products, including milk and yogurt, with different amounts of proteins on responses of appetite, glucose and insulin and on food intake at a meal served 120 minutes later in healthy adult…
- Trial name
- NCT01673321
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Effects of L-Arginine and Citrulline Malate Supplementation on Sport Performance in Physically Active Men
In this randomized, double-blind, placebo-controlled trial we investigated the effects of combined L-arginine (Arg) and citrulline-malate (CM) supplementation on aerobic, anaerobic, and high-intensity interval training in…
- Trial name
- ReachSci (NCT06938126)
- Testing
- L-Arginine and Citrulline-Malate Supplementation
- Where
- Hungary
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hungarian University of Sports Science
Healthy
Study to Determine the Digestive and Physiological Effects of an Extract From Bran in Healthy Men and Women
The primary objective of this trial is to determine whether two doses of an extract from bran demonstrate a prebiotic effect on colonic bacteria (by modulating selected fecal microbial populations, particularly bifidobacteria).
- Trial name
- NCT01073969
- Testing
- wheat bran extract, control wheat bran extract
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kellogg Company
Weight Loss, Gut Microbiome
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
This study will systematically quantify the effects of protein pacing and intermittent fasting (P-IF) on total and regional (abdominal) body composition (lean mass and fat mass), blood glucose and lipids, and anti-aging…
- Conditions
- Weight Loss, Gut Microbiome, Anti-Aging
- Trial name
- NCT04327141
- Testing
- P-IF, HH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Male Contraception
First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males
A single ascending oral dose(s) study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of YCT-529 in healthy male subjects.
- Trial name
- NCT06094283
- Testing
- YCT-529
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- YourChoice Therapeutics, Inc.
Drug-Drug Interaction (DDI), Healthy Subjects
A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men
This study evaluates how a drug that alters liver enzymes (rifampin) affects the metabolism of enzalutamide in men by measuring concentrations of enzalutamide and its metabolites in plasma.
- Conditions
- Drug-Drug Interaction (DDI), Healthy Subjects, Pharmacokinetics of Enzalutamide
- Trial name
- NCT02138799
- Testing
- enzalutamide, rifampin
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Muscle Hypotrophy
The Effect of Blood Flow Restriction (Bfr) Exercise on Acute Systemic Myokine Levels in Healthy Trained Men
The aim of the study is to measure and compare acute systemic irisin, myostatin and decorin levels after a single session of blood flow restricted resistance exercise and resistance exercise without blood flow restriction in…
- Trial name
- NCT05573321
- Testing
- BFR-RE, HL-RE
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ege University
Men, Health Behavior
POWERPLAY: Promoting Men's Health at Work
With funding from the Candian Cancer Society, the Men's Healthy Eating Active Living (MHEAL) project began the development, evaluation, and optimization of a program called POWERPLAY to promote men's health at work.
- Conditions
- Men, Health Behavior, Health Knowledge, Attitudes, Practice, Cancer
- Trial name
- POWERPLAY (NCT03548077)
- Testing
- POWERPLAY
- Where
- Canada
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Volunteers
Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers
This is a single-center, multiple-dose, randomized, double-blind, double-dummy, placebo-controlled, active-comparator, parallel study in healthy volunteers.
- Trial name
- NCT01689116
- Testing
- Bardoxolone Methyl 20mg, Bardoxolone Methyl 80mg, Moxifloxacin 400mg
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Biogen
Calcium Deficiency, Vitamin D Deficiency
Human Pharmacology Trial of Calcium-vitamin D3 Tablet in Healthy Participants
The purpose of this study is to demonstrate that the intestinal absorption of calcium from a newly developed calcium carbonate-vitamin D3 chewable tablet formulation increases the amount of calcium excreted in urine and decreases…
- Trial name
- Osteopro (NCT01639222)
- Testing
- Calcium 500 mg and Vitamin D3 800 IU, Low calcium meals
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy
A Study About How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated in Healthy Japanese Men
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 1358894 in healthy male subjects following oral administration of single rising doses.
- Trial name
- NCT03875001
- Testing
- Dose group 1 - 50 mg BI 1358894, Dose group 2 - 100 mg BI 1358894, Dose group 3 - 200 mg BI 1358894
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Schizophrenia
A Study of the Dose Proportionality of Extended Release Paliperidone
The purposes of this study are to evaluate the dose proportionality of 1.5- and 3 mg tablets of paliperidone ER, to document the pharmacokinetics of a 1.5 mg dose of paliperidone ER, and to assess the safety and tolerability of…
- Trial name
- NCT00791167
- Testing
- Paliperidone ER
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Healthy
A Study to Test How Well Healthy Men Tolerate BI 765250 When Given as an Infusion Into the Vein or as an Injection Under the Skin
The main objectives of this trial are to investigate safety, tolerability, pharmacokinetics and pharmacodynamics following single rising doses of BI 765250.
- Trial name
- NCT05151653
- Testing
- BI 765250
- Where
- Belgium
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim