Clinical trials: Healthy Men
Aging
Effects of NAD3 Supplementation on Biomarkers of Aging
This is a randomized, parallel-group, placebo-controlled, clinical trial in middle-aged and older male and female subjects from Ohio. Subjects will take an over-the-counter dietary supplement or a placebo for 12 weeks.
- Trial name
- NCT04276948
- Testing
- NAD3
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Healthy
Lysine Requirement of Elderly Men and Women Over 60 Years of Age
This study aims to determine the requirement for lysine in men and women over the age of 60 years. Seven different levels of lysine intake will be tested in each subject in random order.
- Trial name
- NCT02008955
- Testing
- Lysine intake provided as a milkshake
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy
A Study in Healthy Men to Test How BI 764198 is Processed in the Body
The main objective of this trial is to investigate the basic pharmacokinetics of BI 764198 and its metabolites, total radioactivity including mass balance, excretion pathways and metabolism following oral administration to…
- Trial name
- NCT05863130
- Testing
- BI 764198 (C-14) (approach 1), BI 764198 (C-14) (approach 2)
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test How BI 1291583 is Processed in the Body
The main objective of this trial is to Assess the mass balance and total recovery of [14C]-radioactivity in urine and faeces following a dose of BI 1291583 (C-14) Provide plasma and urine samples for pharmacokinetic…
- Trial name
- NCT05833035
- Testing
- BI 1291583 mixed with [C-14] BI 1291583
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Men
A Randomized, Double-blind, Single-dose, Two-arm Parallel Study to Compare the Pharmacokinetics and Safety of BAT1806 Prefilled Subcutaneous Injection With RoActemra® in Healthy Chinese Male Subjects
This is a randomized, double-blind, single-dose, two-arm parallel study to compare the pharmacokinetics, safety and immunogenicity of BAT1806 prefilled subcutaneous injection with RoActemra® (from EU) in healthy male subjects.
- Trial name
- NCT05968508
- Testing
- BAT1806 prefilled subcutaneous injection/RoActemra® (from EU)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bio-Thera Solutions
Healthy
A Study to Test How Healthy Men Tolerate Different Doses of BI 1595043
The primary objectives of this trial are to investigate safety and tolerability of BI 1595043 in healthy male subjects following administration of multiple rising doses over 14 days.
- Trial name
- NCT04789304
- Testing
- BI 1595043, Midazolam
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Postmenopausal, Osteopenia
A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Romosozumab (AMG 785)
The primary objective of this study was to assess the safety, tolerability, and immunogenicity potential of romosozumab following multiple subcutaneous (SC) administrations in healthy men and postmenopausal women with low bone…
- Trial name
- NCT01825785
- Testing
- Romosozumab
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Amgen
Healthy
A Study to Test How Different Doses of BI 1815368 Are Tolerated and How BI 1815368 is Taken up in the Body of Healthy Japanese Men
The main objectives of this trial are to investigate safety, tolerability. pharmacokinetics (PK), and pharmacodynamics of BI 1815368 in healthy Japanese male subjects following administration of single rising doses or multiple…
- Trial name
- NCT06494774
- Testing
- BI 1815368
- Where
- Japan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Safety and Tolerability of Lu AF95245 in Healthy Young Men
The purpose of this study is to investigate the safety and tolerability of Lu AF95245 and what the body does to Lu AF95245 after swallowing single doses of the drug
- Trial name
- NCT04199585
- Testing
- Lu AF95245, Lu AF95245 14C radiolabelled spiked dosage
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy
Study That Evaluates the Effect of CYP3A4 Inhibition on Lu AG06466 in Healthy Men and Women
A study to learn how a drug (itraconazole) that is known to inhibit a certain enzym in the liver, impacts the body's ability to breakdown Lu AG06466 into breakdown products in healthy men and women.
- Trial name
- NCT04405323
- Testing
- Lu AG06466, Itraconazole
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Males, Men
Effects of Short- Term Intermittent Fasting Aerobic and Anaerobic Capacity
The therapeutic use of caloric restriction and intermittent fasting (IF) protocols improves life span and health related quality of life.
- Trial name
- Performance (NCT04756635)
- Testing
- Experimental Group
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Type 2 Diabetes, Stroke
The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men During Hypoglycemia
Type 2 diabetes mellitus, T2D is a disease characterized by an immense growing prevalence world wide with an increased risk of myocardial infarction and stroke.
- Conditions
- Type 2 Diabetes, Stroke, Myocardial Infarction
- Trial name
- NCT00418288
- Testing
- glucagon-like-peptide-1
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obesity
Mirabegron and Brown Adipose Tissue
Obesity and type 2 diabetes (T2D) are emerging problems worldwide. In particular South Asian individuals (representing 20% of the world population) have an increased risk of obesity and related disorders.
- Trial name
- Mirab (NCT03012113)
- Testing
- Mirabegron, Short term mild cooling
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ingrid Jazet
Healthy Males
Effect of a 4-week Post-exercise Sauna Bathing on Targeted Gut Microbiota
Body temperature fluctuations induced by acute exercise bouts may influence the intestinal barrier with related effects on epithelial permeability, immune responses, and release of metabolites produced by the gut microbiota.
- Trial name
- NCT05277597
- Testing
- The exercise 60 minutes, 3 times per week, on a bicycle ergometer followed by a 30-minute dry Finish sauna treatment., The same exercise training program without the sauna treatments
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Healthy
A Study in Healthy Men and Women to Test Which Effects Memantine and BI 425809 Have on Each Other
Investigate the effect of steady state exposures of memantine on the steady-state pharmacokinetics of BI 425809 and vice versa in healthy subjects.
- Trial name
- NCT03988803
- Testing
- BI 425809, Memantine
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Exercise
Protein Supplementation and Endurance Exercise Adaptations
Participants will perform three endurance training sessions weekly for 12 weeks. All participants will be randomly assigned to the protein supplementation group or the placebo (iso-caloric carbohydrate) group.
- Trial name
- NCT03462381
- Testing
- Protein
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Healthy
A Study to Test How Different Doses of BI 456906 Are Tolerated in Japanese Men With a Body Mass Index (BMI) Between 23 and 40 kg/m2
Main objectives are to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of different dose escalation schemes of BI 456906 in healthy Japanese male subject with BMI 23-40 kg/m2 and to determine a dose…
- Trial name
- NCT04384081
- Testing
- BI 456906
- Where
- Japan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Constipation, Bloating
Impact of the Inno Cleanse Dietary Supplement on Gut Health and Associated Variables in Healthy Men and Women
The purpose of the present study is to investigate the impact of a natural dietary supplement, Inno Cleanse™, to reduce bloating in a population of otherwise healthy men and women, who claim to feel frequently bloated.
- Trial name
- NCT07215351
- Testing
- Dietary supplement for digestive health
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Cancer Prevention
HAT TRICK: An Innovative Health Promotion Program for Men
The purpose of this research is to implement and evaluate the feasibility of the HAT- TRICK Program, a gender- sensitive intervention program targeting physical activity, healthy eating and connectedness in men living in the…
- Trial name
- NCT03059199
- Testing
- Single-Arm Feasibility Study
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Inflammation
Investigation of the Distinct Mechanisms Involved in Inflammatory Resolution Between Healthy Men and Women
Important differences exist between sexes in incidence, disease patterns and outcomes in coronary artery disease that is not well understood.
- Trial name
- RESOLVE-SEX (NCT05597098)
- Testing
- Cantharidin
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London