Clinical trials: Healthy Men and Women
Pre-diabetes, Metabolic Syndrome
Replacing Refined Carbohydrates With Healthy Fats on Cardio-metabolic Markers
The primary goal is to to characterize the effects of consuming 1 avocado fruit 7 days / week (5-7 days is acceptable) compared to a no avocado relatively low fat, carbohydrate control treatment over a 12 week period on insulin…
- Trial name
- AV2 (NCT02695433)
- Testing
- Active, Control
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Muscle Hypertrophy, Healthy and Well-Trained Men and Women
Time-Restricted Eating and Muscle Hypertrophy
The purpose is to examine the effects of time-restricted eating (TRE; consuming all calories within an 8-hour period each day) vs.
- Trial name
- NCT04000750
- Testing
- Time Restricted Eating, Normal Feeding, Resistance Training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- California State University, Fullerton
Healthy Men and Women
Effects of an Organic Plant-rich Diet on Gut Microbiome and Vascular Function (ORGAMIC Pilot Study)
Previous work have shown that consumption of foods rich in polyphenols, such as berries and cocoa, led to beneficial changes in the gut microbiota composition, as well as improvements in biomarkers of cardiovascular disease risk…
- Trial name
- NCT04276974
- Testing
- Organic diet, Non-organic diet
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy
Bioequivalence Study to Compare Two Formulations of Deanxit®
The purpose of this study is to establish bioequivalence of flupentixol/meltracen, between a new film-coated tablet formulation and the marketed coated tablet formulation (Deanxit®), administered single dose in fasted and fed…
- Trial name
- NCT03472651
- Testing
- test treatment: flupentixol/melitracen, reference treatment: flupentixol/melitracen
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Volunteers
Study to Evaluate and Compare the PK Profiles of Abaloparatide-SC and Abaloparatide-sMTS in a Cohort of Healthy Men and Healthy Women.
A study to evaluate and compare the PK profiles of abaloparatide-SC 80 μg and abaloparatide-sMTS 300 μg in a cohort of healthy men and to make a similar evaluation in a cohort of healthy women
- Trial name
- NCT04663464
- Testing
- abaloparatide-sMTS, abaloparatide-SC
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Radius Health, Inc.
Healthy
A Study in Healthy Men and Women to Test Whether BI 1358894 Influences the Amount of Bupropion in the Blood
The main objective of this trial is to investigate the relative bioavailability of a single dose of bupropion when given alone (Reference) compared with co-administration (Test) with BI 1358894 in healthy volunteers.
- Trial name
- NCT04899674
- Testing
- Elontril, BI 1358894
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Tolerance
Tolerance and Safety of a Ketone-Promoting Food Ingredient
The objective of this study is to capture information on tolerance and safety of a ketone-promoting food ingredient in healthy adults.
- Trial name
- NCT04707989
- Testing
- Ketone- Promoting Food Ingredient #1, Ketone- Promoting Food Ingredient #2
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- BHB Therapeutics, Ireland LTD
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes
A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women
Researchers are looking for a better way to treat vasomotor symptoms (VMS), also known as hot flashes. Hot flashes are intense and sudden feelings of heat along with sweating and reddening of the skin.
- Trial name
- NCT06219902
- Testing
- Elinzanetant (BAY3427080), Zopiclone
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
A Study in Healthy Men and Women to Test How Well Different Doses of BI 1323495 Are Tolerated
The primary objective of this trial is to investigate the safety and tolerability of BI 1323495 in healthy subjects following bid oral administration of multiple rising doses, each over an 11 day treatment period.
- Trial name
- NCT04107805
- Testing
- BI 1323495, Midazolam
- Where
- Germany
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Tolerance, Safety Issues
Buck Institute Ketone Ester RCT
This study is to investigate the tolerability and safety of a ketone promoting ingredient, called a ketone ester (KE), in healthy older adults.
- Conditions
- Tolerance, Safety Issues, Aging
- Trial name
- BIKE (NCT05585762)
- Testing
- Ketone ester
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Buck Institute for Research on Aging
Sarcopenia, Osteopenia
Nutrient Support to Body Composition and Healthy Ageing
The focus is healthy ageing, i.e. delaying the deterioration in health status in older adults. Loss of lean tissue (skeletal muscle) mass, a process termed sarcopenia, or bone tissue mass, a process called osteopenia, is a…
- Trial name
- BCHA (NCT02529124)
- Testing
- CONTROL, PROTEIN, PHYSICAL ACTIVITY
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Phil Jakeman
Healthy Subjects
To Study the Effect of Aprocitentan on the Electrical Activity of the Heart in Healthy Men and Women
To demonstrate that multiple-dose administration of oral therapeutic and supratherapeutic doses of aprocitentan do not have a clinically relevant effect on the QT interval.
- Trial name
- NCT04281342
- Testing
- Aprocitentan 25 mg, Aprocitentan 100 mg, Moxifloxacin control to establish assay sensitivity
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Healthy
Bioequivalence Study of Zonisamide Capsules 100 mg of Dr.Reddy's Laboratories Limited Under Fasting Conditions
The objective of this study was to compare the rate and extent of absorption of Dr. Reddy's Zonisamide 100 mg Capsule to that of Zonegran® 100 mg Capsule after a single, one-capsule dose in fasted subjects.
- Trial name
- NCT01161966
- Testing
- Zonisamide, Zonegran
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
Drug Drug Interaction Study With Lu AG06466 in Young Healthy Men
The purpose of this study is to evaluate the effect of repeated doses of the drug Lu AG06466 on the exposure of metoprolol, midazolam and bupropion
- Trial name
- NCT04713254
- Testing
- Lu AG06466, Midazolam, Metoprolol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Wellness, Health
A Crossover Clinical Trial Investigating the Effects of Geranylgeraniol (GG) Supplementation on Testosterone Levels in Healthy Men and Women Over an 18-week Period
The primary purpose of this study is to investigate the effects of geranylgeraniol (GG) supplementation on testosterone levels in middle-aged (40 to 65 years) healthy men and women.
- Trial name
- NCT06747624
- Testing
- Geranylgeraniol 300 mg
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Designs for Health
Parkinson's Disease
Pharmacokinetic Properties of Rasagiline (Lu 00-773) in Healthy Young Chinese Men and Women
The purpose of this study is to fulfil regulatory requirements for registration of a new chemical entity in China. Rasagiline is approved for the treatment of Parkinson's Disease (PD) in Europe and the US.
- Trial name
- NCT01652313
- Testing
- Rasagiline
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy
Blood Nitrate/Nitrite Concentrations Following Acute Ingestion of Resync in Men and Women
This study evaluates acute ingestion of the dietary supplement Resync on blood nitrate/nitrite concentrations in a sample of men and women.
- Trial name
- NCT04125940
- Testing
- Resync, Resync + Collagen
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes
A Study to Learn How the Study Drug Elinzanetant (BAY 3427080) Affects the Way the Drug Dabigatran Moves Into, Through and Out of the Body in Healthy Male and Female Participants
Researchers are looking for a better way to treat men and women with vasomotor symptoms, a condition of having hot flashes caused by hormonal changes.
- Conditions
- Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes, Healthy Volunteers
- Trial name
- NCT05471817
- Testing
- Elinzanetant (BAY3427080), Dabigatran etexilate
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bayer
Anemia
A Study of the Electrocardiogram Effects and Pharmacokinetics of Ferumoxytol in Healthy Men and Women
This study will define the effects of ferumoxytol on electrocardiogram (ECG) data as well as evaluate pharmacokinetics
- Trial name
- NCT00360425
- Testing
- ferumoxytol, moxifloxacin
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- AMAG Pharmaceuticals, Inc.
Normal Drug Tolerance
Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women
This is a phase 1, open-label, randomized pharmacokinetic and safety study in healthy adult subjects, who will undergo bronchoscopy and bronchoalveolar lavage (BAL) after receiving seven (7) doses of 1.0 mg/kg IV TP-434.
- Trial name
- BAL (NCT01989949)
- Testing
- TP-434 (Eravacycline) reconstituted and administered via an IV infusion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tetraphase Pharmaceuticals, Inc