Clinical trials: Healthy Older Adults
Healthy
Pharmacokinetics Study for Probucol
To evaluate the safety and pharmacokinetics of probucol by multiple oral administration in healthy male subjects.
- Trial name
- NCT01000467
- Testing
- probucol
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Obesity, Insulin Resistance
A Trial to Study the Effect of Long Term Vitamin D Supplementation on Insulin Sensitivity
Type 2 diabetes is a major public health problem in India with an estimated a prevalence of approximately 4% and 12% in rural and urban areas respectively.
- Trial name
- LongtermVitD (NCT01052181)
- Testing
- Cholecalciferol
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Dr Jitender Nagpal
Healthy, Osteopenia
Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-preFX (NCT06567054)
- Testing
- Measurements with the POROUS R3C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine, DXA-based Vertebral Fracture Assessment (VFA)
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Infections, Meningococcal
Immunogenicity and Safety Study of GSK Biologicals' Meningococcal Vaccine Given as One Dose to Healthy Subjects Above 56 Years
This study evaluates the immunogenicity and safety of the meningococcal conjugate vaccine GSK 134612 given as single dose to healthy adults 56 years or older compared to the meningococcal polysaccharide vaccine MencevaxACWYTM.
- Trial name
- NCT01235975
- Testing
- Meningococcal vaccine GSK 134612, MencevaxACWY TM
- Where
- Lebanon
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Charcot-Marie-Tooth Disease
Observational Study of Neuromuscular Function in CMT Type 1&2 and Healthy Controls
The primary aim of this study is to discover whether patients with CMT type 1 and 2 have neuromuscular junction transmission deficits.
- Trial name
- ESTABLISH (NCT04980807)
- Where
- 2 sites in United States, Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NMD Pharma A/S
Infections, Papillomavirus
Complementary Testing to Evaluate Immunogenicity of Human Papillomavirus (HPV) Vaccine (580299) in Healthy Female Subjects Aged >/= 26 Years
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Indeed, certain oncogenic types of HPV can infect the cervix (part of the uterus or womb).
- Trial name
- NCT00456807
- Testing
- Cervarix TM
- Where
- 2 sites in Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Retirement, Healthy Adults
Transitions and Old Age Potential - 1st, 2nd, and 3rd Wave
With the third wave of the Transitions and Old Age Potential (TOP) study, the longitudinal study of initially 5,002 individuals was completed in 2019.
- Conditions
- Retirement, Healthy Adults, Elderly
- Trial name
- TOP (NCT07301112)
- Volunteers
- 5,002 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Healthy
Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Japanese Adults Aged >= 50 Years
The purpose of this study is to evaluate the safety, tolerability, and immunogenicity of the 13-valent pneumococcal conjugate (13vPnC) vaccine in healthy Japanese adults aged >= 50 years.
- Trial name
- NCT00562354
- Testing
- 13vPnC
- Where
- 2 sites in Japan
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Pfizer
Respiratory Syncytial Virus Infections
A Study on the Safety and Immune Response to an mRNA-based RSV Investigational Vaccine in Healthy Adults Aged 18-45 Years
The purpose of this study is to assess the reactogenicity, safety and immune response of various formulations of the RSV mRNA investigational vaccine administered in healthy participants 18-45 years of age.
- Trial name
- NCT06573281
- Testing
- Investigational RSV vaccine 1, Investigational RSV vaccine 2, Investigational RSV vaccine 3
- Where
- 9 sites in United States, Australia and 1 more
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pneumococcal Infections
13-valent Pneumococcal Conjugate Vaccine Study in Adults => 50 Years of Age in Mexico
The purpose of this study will be to assess the safety, tolerability, and immunogenicity of 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) when given to healthy adults older than 50 years of age who haven't received 23-valent…
- Trial name
- NCT01432262
- Testing
- vaccine-13vPnC
- Where
- 4 sites in Mexico
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Pfizer
COVID-19 Pandemic
Clinical Study for Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01) Booster Immunization
A Clinical Study to Evaluate the Immunogenicity and Safety of Sequential Immunization of Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01) Against COVID-19 in Healthy Adults Aged 18 Years and Older After the Vaccination of 2…
- Trial name
- COVID-19 (NCT05125874)
- Testing
- Recombinant SARS-CoV-2 Fusion Protein Vaccine
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Livzon Pharmaceutical Group Inc.
Mild Cognitive Impairment (MCI), Healthy Aging
cMIND AI Web Tool Usability Study (Hong Kong)
This study is testing a new web-based tool that uses artificial intelligence (AI) to help older adults in Hong Kong check how healthy their Cantonese-style meals are for brain health.
- Conditions
- Mild Cognitive Impairment (MCI), Healthy Aging, Nutrition
- Trial name
- NCT07735013
- Testing
- Web-Based AI Dietary Assessment System
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Healthy Participants
A Study of IVX-A12 in Adults Participants
The primary purpose of this study is to assess the immunogenicity and safety of IVX-A12 in adults 60 years of age and older.
- Trial name
- NCT06481579
- Testing
- IVX-A12, Licensed RSV Vaccine
- Where
- 5 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Icosavax, Inc.
Alzheimer's Disease
Safety of Three Formulations of Ketasyn Administered for 14 Days in Healthy Elderly
AC-1202 (Ketasyn) is a nutritional beverage currently being studied in neurodegenerative conditions including Alzheimer's disease.
- Trial name
- NCT00660088
- Testing
- Ketasyn
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cerecin
Diphtheria, Tetanus
Phase I Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed .
Pertussis, diphtheria and tetanus are seriously infectious diseases in children. Since using of the vaccine targeted the three components, it greatly reduced incidence of the three kinds of diseases.
- Conditions
- Diphtheria, Tetanus, Pertussis
- Trial name
- PCTDTcP (NCT04099303)
- Testing
- Diphtheria,Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed, Diphtheria and Tetanus Combined Vaccine, Adsorbed, Diphtheria-tetanus-acellular pertussis vaccine
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Healthy Volunteers, Pharmacokinetics of Mirabegron
A Study to Evaluate How Mirabegron Enters and Leaves the Bloodstream According to Age and Sex
Young and elderly, male and female subjects are each given 2 different doses of mirabegron for 7 days each. Levels of mirabegron in the blood are assessed.
- Trial name
- NCT01285596
- Testing
- Mirabegron
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy
Single Increasing Doses of BIII 890 CL in Healthy Young Male Volunteers and in Healthy Elderly Male and Female Volunteers
Safety, tolerability and pharmacokinetics of BIII 890
- Trial name
- NCT02269215
- Testing
- BIII 890 CL
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Alteration of Cognitive Function
Cognitive Effects of Tai Chi Chuan in Healthy Older Adults and Older Adults
Background: Promotion of cognitive functions of middle aged and older adults and prevention of dementia are important issues in the aging society.
- Trial name
- NCT02270320
- Testing
- Physical activity
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy Volunteers
Marine Protein Hydrolysate as Dietary Supplement in Elderly Part I
The aim of this study is to investigate the potential effect of a marine protein hydrolysate (MPH) supplement before a meal on postprandial glucose tolerance in healthy subjects, to achieve more knowledge on this presumed…
- Trial name
- MPH-BS (NCT03669796)
- Testing
- Marine protein hydrolysate (mph), Control
- Where
- 2 sites in Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Helse Møre og Romsdal HF
Healthy
The Effect of Relaxation Response Training on Declarative Memory and Salivary Cortisol in Older Adults
To evaluate whether a 5-week relaxation response intervention influences the learning, memory or attention of healthy older adults.
- Trial name
- NCT00179530
- Testing
- Relaxation Response
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
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