Clinical trials: Healthy Older Adults
Elderly (People Aged 65 or More), Rural Health
Static-dynamic Balance Training Combined With Reminiscence Therapy
The SDBT-RT Program: A Holistic Approach for Rural Older Adults We developed the Static-Dynamic Balance Training Combined with Reminiscence Therapy (SDBT-RT) program to help older adults in rural communities adopt healthier…
- Trial name
- SDBT-RT (NCT07085884)
- Testing
- The Static-Dynamic Balance Training Combined with Reminiscence Therapy
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Xinyu Yang
COVID-19
A Study to Evaluate the Efficacy, Safety and Immunogenicity of SARS-CoV-2 Vaccine (Vero Cells), Inactivated in Healthy Adults Aged 18 Years and Older (COVID-19)
The study will be a multi-national, endpoint-driven, randomized, double-blind, placebo-controlled, adaptive study in which participating adults will be randomized 1:1 to receive 2 doses of either candidate vaccine or placebo on…
- Trial name
- NCT04852705
- Testing
- SARS-CoV-2 Vaccine (Vero Cells), Inactivated
- Volunteers
- 28,000 people, healthy volunteers welcome
- Sponsor
- Shenzhen Kangtai Biological Products Co., LTD
Hepatitis B
Safety and Immunogenicity of GSK Bio's Candidate HBV-MPL Vaccines Compared to Engerix™-B, in Healthy Adolescents
In this study the safety and immunogenicity of 2 different formulations of the candidate HBV-MPL vaccine administered according to a 0, 6-month schedule were explored and compared to that of Engerix™-B in healthy adolescents aged…
- Trial name
- NCT00697775
- Testing
- HBV-MPL vaccine Formulation A, HBV-MPL vaccine Formulation B, Engerix™-B
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Balance Disorders, Fall
Action Observation and Exercise for Balance in Older Adults: A Randomized Trial.
The primary objective is to evaluate the effectiveness of combining action observation with a therapeutic exercise program to improve balance and prevent falls in adults aged ≥65 with low to moderate fall risk.
- Conditions
- Balance Disorders, Fall, Elderly (People Aged 65 or More), Exercise
- Trial name
- AOBAL (NCT07199790)
- Testing
- Action observation videos, Therapeutic exercise
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Alzheimer Disease, Healthy
Study Evaluating the Safety, Tolerability and Activity of One Dose of PAZ-417 Given to Healthy Japanese Subjects
This study will provide an initial assessment of the safety, tolerability, and pharmacokinetics (PK) of PAZ-417 after administration of ascending single oral doses to healthy young Japanese male and healthy elderly Japanese male…
- Trial name
- NCT00684710
- Testing
- PAZ-417
- Where
- Japan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Loneliness, Social Isolation in Older Adults
The ALIVE-Project: Activity, Life Satisfaction, Inclusion, Vitality, Elderly Women
Many older women live alone and may experience loneliness, reduced social participation, and declining physical health. Regular physical activity can improve health and independence, but it is not known whether exercising in a…
- Conditions
- Loneliness, Social Isolation in Older Adults, Physical Inactivity, Healthy Ageing
- Trial name
- ALIVE (NCT07789080)
- Testing
- Supervised Group Exercise in Fitness Clubs, Individual exercise
- Where
- Norway
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Cardiovascular Diseases, Aging
Cardio-vascular Protective Effects of Wolfberry in Middle-aged and Older Adults
This purpose of this study is to assess the impact of consuming wolfberry on cardiovascular risk in Singapore's middle-aged and older adults.
- Trial name
- NCT03535844
- Testing
- Wolfberry, Healthy diet
- Where
- 2 sites in Singapore
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Healthy
Health Effects of Milk Proteins in Elderly Subjects
The aim of the present study is to investigate effects of milk on body composition and muscle strength, inflammation, appetite, DNA damage/repair and PBMC whole genome transcriptomics in elderly subjects.
- Trial name
- NCT02218333
- Testing
- Milk
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Individuality, Healthy
Vaccination Responses in Young and Older Adults
To follow longitudinally healthy and immune-compromised responses to pneumococcal vaccination, in 60+ individuals towards the development of personalized medicine implementation (minimum enrollments in 2 age categories: young…
- Conditions
- Individuality, Healthy, Asthma, Immune System and Related Disorders
- Trial name
- NCT02654704
- Testing
- Pneumococcal Vaccination
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Michigan State University
the Immediate and Long-lasting Effects of the X10D Sole on Important Aspects of Walking Function in Healthy Participants, Walking
Studying the Effects of the X10D Shoe on Walking in Healthy Adults Aged 50 to 65
The aim of this study is to characterize the biomechanical effects of the X10D sole using objective, quantitative measurement methods.
- Trial name
- NCT07296913
- Testing
- X10D shoe
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Mild Cognitive Impairment, So Stated, Mild Dementia
Cognitive/Physical Computer-Game Blended Training With Personalized Brain Network Activation Technology for the Elderly
The study involves a novel Virtual Reality Interface that offers full-body immersion "Alterniity AR" and more specifically computer exercises blended with game activities.
- Conditions
- Mild Cognitive Impairment, So Stated, Mild Dementia, Healthy
- Trial name
- AlterniityAR (NCT02417558)
- Testing
- Alterniity Augmented Reality (AAR), VideoGrade
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- XtremeVRI AG
Respiratory Syncytial Virus Infections
A Study to Describe the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine IN006 in Healthy Adult Aged 18 Years and Above
The study will evaluate the safety, tolerability, and immunogenicity of 3 dose levels of IN006 in healthy adults aged 18 Years and Above; of a revaccination of IN006 given approximately 12 months after the initial vaccination in…
- Trial name
- NCT06645665
- Testing
- Bivalent RSV Vaccine (IN006)
- Where
- 2 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Shenzhen Shenxin Biotechnology Co., Ltd
Healthy Volunteers
A Food-Effect Study of AND017 in Healthy Participants
The purpose of this phase I study is to evaluate the food effect on the PKs of AND017 following oral single-dose administration in healthy non-elderly Chinese subjects.
- Trial name
- NCT04712500
- Testing
- AND017
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kind Pharmaceuticals LLC
Hepatitis B, Hepatitis A
Long Term Follow-up Study at Years 2, 3, 4 and 5 Where 2 Dosing Schedules of the Combined Hepatitis A and B Vaccine Were Compared
To evaluate the persistence of anti-hepatitis A virus (HAV) and anti-hepatitis B surface antigen (HBs) antibodies up to 2, 3, 4 and 5 years after administration of the first dose of the study vaccine.
- Trial name
- NCT00197184
- Testing
- Twinrix™ Adult, Twinrix™ Junior
- Where
- 7 sites in Australia, Belgium and 1 more
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza
Safety and Immunogenicity of GPO Seasonal Trivalent Inactivated Influenza Vaccine in Healthy Thai Adults
The study is aim to evaluate the safety and immunogenicity of one dose (15 μg HA per strain per dose) of the GPO seasonal trivalent inactivated split virion influenza vaccine (Tri Fluvac) in healthy adults aged 18 to 49 years…
- Trial name
- NCT02894840
- Testing
- an inactivated influenza vaccine
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Health Behavior, Health Literacy
Social Cognitive Theory-Based Education for Improving Health Outcomes in Older Adults
This study aims to evaluate the effectiveness of a Social Cognitive Theory-based education program on self-efficacy, healthy lifestyle behaviors, and health literacy in older adults aged 65 years and over attending primary care…
- Conditions
- Health Behavior, Health Literacy, Self Efficacy, Aging
- Trial name
- SCT-OLD (NCT07566143)
- Testing
- Social Cognitive Theory-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Muhammet Faruk Yigit
Influenza Immunization, Healthy Volunteers
Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Japanese Adults 60 Years of Age and Older
Primary Objective: To demonstrate that QIV-HD induced an immune response (as assessed by hemagglutination inhibition [HAI] geometric mean titers [GMTs] and seroconversion rates) that was superior to responses induced by QIV-SD…
- Trial name
- NCT04498832
- Testing
- High-Dose Quadrivalent Influenza Vaccine, (Zonal Purified, Split Virus) 2020-2021 Strains (QIV-HD), Local Standard-Dose Inactivated Quadrivalent Influenza Vaccine, 2020-2021 Strains (QIV-SD)
- Where
- 10 sites in Japan
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Healthy
Determination of Protein Requirement in Elderly Male Subjects >75 Yrs Old
Minimal data are available on protein requirements throughout the lifespan. Currently available recommendations are based on nitrogen balance data. The limitations of the nitrogen balance method have been well described.
- Trial name
- NCT01948492
- Testing
- Protein intake
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy Older Adults
tDCS Effects on Associative Learning in Older Adults of Retirement Age
The aim of this study is to investigate whether a tDCS-accompanied training of audio-visual associative memory leads to a performance improvement in healthy older individuals.
- Trial name
- TRAINSTIM2 (NCT02839993)
- Testing
- tDCS, training
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy Participants
Peroneal Muscles Response to Expected and Unexpected Falls Among Young and Middle-aged Adults Before and After Neuromuscular Training
Proper functioning of the ankle musculature, specifically peroneal muscles, is crucial for maintaining balance and reducing the risk for falls.
- Trial name
- NCT05006547
- Testing
- Electromyograph Biofeedback training of the peroneal muscle
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ariel University
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