Clinical trials: Healthy Older Adults
Healthy
Effect of a Multinutrient-Optimized Infant Formula Supplemented With Human Milk Oligosaccharides on Infant Growth and Development: A Multicenter, Randomized, Controlled Trial
This study aims to learn about a newly developed infant formula that adds two special ingredients found in breast milk (human milk oligosaccharides, HMOs) and improves other nutrients.
- Trial name
- NCT06569797
- Testing
- Human Milk Oligosaccharide-Supplemented, Multi-Nutrient Optimized Infant Formula, Commercially Available Standard Formula, Breast Milk Feeding
- Where
- 6 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Healthy Volunteers
A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP7713 in Healthy Non-Japanese Adult and Elderly Subjects and Healthy Japanese Adult Subjects
This is a combined Single and Multiple Ascending Oral Dose Study. Part 1 is a Single Ascending Dose (SAD) and Part 2 is Multiple Ascending Dose (MAD).
- Trial name
- NCT03108755
- Testing
- ASP7713
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Respiratory Syncytial Virus (RSV)
Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.
This study will enroll subjects who received the RSV F vaccine or placebo in the earlier study (RSV-E-201, Year 1) and re-randomize them to receive either vaccine or placebo in a second season.
- Trial name
- NCT02593071
- Testing
- RSV-F Vaccine
- Where
- 10 sites in United States
- Volunteers
- 1,330 people, healthy volunteers welcome
- Sponsor
- Novavax
Healthy Ageing, Community-dwelling Older Adults
Intrinsic Capacity, Resilience, and Meaning in Life in Community-Dwelling Midlife and Older Adults
This prospective observational cohort (panel) study aims to understand how intrinsic capacity, resilience, and meaning in life are related and how they change over time in community-dwelling middle-aged and older adults who…
- Trial name
- NCT07687563
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Yang Ming Chiao Tung University
Knee Osteoarthristis, Healthy Adults
Digital Course and Precision Rehabilitation for Knee Osteoarthritis and Older Adults: Integration of Multisensory Stimulation and Digital Twin Technology
Knee osteoarthritis (OA) is a common degenerative joint disease in middle-aged and older adults and is frequently associated with pain, quadriceps weakness, reduced mobility, impaired proprioception, balance deficits, and…
- Trial name
- NCT07695168
- Testing
- digital rehabilitation exercise courses combined with multisensory stimulation, Home exercises based on therapist education, Gait retraining combined with neuromuscular electrical stimulation
- Where
- 3 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Bacterial Infections
To Evaluate the Pharmacokinetics of XNW4107 in Healthy Adult Young Females and in Healthy Adult Elderly Males and Females.
This is a Phase 1, randomized, double-blind, placebo-controlled study to assess the PK, safety and tolerability of XNW4107, imipenem and cilastatin administered by 60-min (± 3 min) IV infusion in healthy adult young females and…
- Trial name
- NCT04801043
- Testing
- XNW4107, Imipenem/Cilastatin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Evopoint Biosciences Inc.
Nutrition, Healthy, Elderly
Study on the Relationship Between Iodine Nutrition and Thyroid Diseases in the Elderly
The aging trend of China's population is intensifying. More than 50% of the elderly in China suffer from thyroid disease. Thyroid dysfunction in the elderly increases the risk of cardiovascular and metabolic diseases.
- Trial name
- NCT05716191
- Testing
- Naturally different iodine levels exposure
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Varicella
Immunogenicity and Safety of Varicella Vaccine, Live in Healthy Children Aged 12~15 Months in the Philippines
This is a Phase Ⅲ, randomized, double-blind, active-controlled study to assess the immunogenicity and safety of the varicella vaccine,Live (hereinafter referred to as "varicella vaccine")manufactured by Sinovac (Dalian) Vaccine…
- Trial name
- NCT06314724
- Testing
- Varicella Vaccine, Varivax
- Where
- 2 sites in Philippines
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Sinovac (Dalian) Vaccine Technology Co., Ltd.
Influenza Caused by the Novel Influenza A (H1N1) Virus
A Clinical Trial of CSL's 2009 H1N1 Influenza Vaccine (CSL425) in Healthy Children
The purpose of this study is to determine whether CSL425 is a safe and effective vaccine for eliciting an immune response to H1N1 influenza in healthy children.
- Trial name
- NCT00940108
- Testing
- CSL425
- Where
- 5 sites in Australia
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Seqirus
Healthy Aging
Adopting a Health-social Partnership Program to Promote Health and Self-care Management Among Older Adults in the Community
Hong Kong has notably the longest life expectancy in the world. Ever-increasing demand and challenges are posing to the healthcare, social welfare, and elderly care service system.
- Trial name
- NCT05621720
- Testing
- Case management, Social control call and usual are
- Where
- Hong Kong
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Influenza
Study to Evaluate Safety, Tolerability and Immunogenicity of a Bedside Mixing Combination of Two Adjuvanted Influenza Vaccines
This trial is designed to evaluate safety, tolerability and immunogenicity of a bedside mixing formulation of adjuvanted influenza vaccines.
- Trial name
- NCT00735020
- Testing
- Adjuvanted Influenza Vaccine, Influenza Vaccine
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Healthy
A Study to Evaluate Safety, Tolerability, and PK of DA-7503 in Healthy Adult and Elderly Participants
This is a double-blind, placebo-controlled, randomized, phase 1 study to evaluate safety, tolerability, and pharmacokinetics of orally administered DA-7503 after single and multiple ascending dose regimens in healthy adult and…
- Trial name
- NCT06391827
- Testing
- DA-7503 Single dose, DA-7503 Multiple dose
- Where
- South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
HPV InfectioN, HPV-Related Carcinoma
A Study to Evaluate the Efficacy, Safety, and Immunogenicity of SCT1000 in Healthy Women Aged 18-45 Years
A total of 18000 healthy women aged 18-45 years old were divided into three age groups: 18-26 years old, 27-35 years old, and 36-45 years old. The experimental group and the placebo group were randomly assigned in a ratio of 1:1.
- Trial name
- NCT06041061
- Testing
- Recombinant 14-Valent Human Papillomavirus Vaccine（Insect Cell）
- Where
- 5 sites in China
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Fall, Aging
PRE.C.I.S.A - Fall Prevention and Promotion of Active and Healthy Aging
Randomized Controlled Trial (RCT) aiming at assessing the efficacy of an interdisciplinary multi-component and personalized multi-factorial intervention for reducing falls at one year post-enrolment in comparison to the usual…
- Conditions
- Fall, Aging, Parkinson Disease, Stroke
- Trial name
- PRECISA (NCT03592420)
- Testing
- Interdisciplinary multicomponent interventions, Usual care
- Where
- 2 sites in Italy
- Volunteers
- 366 people
- Sponsor
- Azienda Unita' Sanitaria Locale Di Modena
Healthy
Effect of Moisturizer on Malaysian Women Facial Skin
The goal of this clinical trial is to evaluate the effect of Product X on facial skin of middle-aged women in Malaysia. The main questions it aims to answer are: 1.
- Trial name
- NCT05657379
- Testing
- Other: Product X moisturizer
- Where
- Malaysia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- USMARI Research & Innovation Centre
Herpes Zoster
A Study to Evaluate the Safety and Immunogenicity of ChAdOx1-VZV in Healthy Adults Aged 50-65 Years
This is a randomized, observer blind and controlled study. Participants in low-dose and high-dose IM group will be randomized in a ratio of 2:1 to receive either the investigational product or the control.
- Trial name
- NCT05991427
- Testing
- Recombinant Zoster Vaccine (Adenovirus Vector) (ChAdOx1-VZV), Zoster Vaccine Recombinant, Adjuvanted (Shingrix), ChAdOx1-VZV
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Intrinsic Capacity
Multidomain Intervention Based on ICOPE
FORMULA 100 is a prospective, single-arm feasibility study conducted at two Active Ageing Centers in Monza, Italy, involving community-dwelling adults aged 65 years and older.
- Trial name
- FORMULA 100 (NCT07829120)
- Testing
- Multidomain intervention
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- University of Milano Bicocca
Healthy Volunteers
Annual Study to Investigate Inactivated Virosomal Influenza Vaccine for the 2006/2007 Influenza Season in Europe.
Influenza (flu) viruses change continuously, therefore also the parts of viruses used in influenza vaccines can vary from year to year.
- Trial name
- NCT00345462
- Testing
- Trivalent virosomal influenza vaccine
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Solvay Pharmaceuticals
the Immediate and Long-lasting Effects of the X10D Sole on Important Aspects of Walking Function in Healthy Participants, Walking
Studying the Effects of the X10D Shoe on Walking in Healthy Adults Aged 50 to 65
The aim of this study is to characterize the biomechanical effects of the X10D sole using objective, quantitative measurement methods.
- Trial name
- NCT07296913
- Testing
- X10D shoe
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Infections, Meningococcal
Evaluate 4 Different Formulations of Meningococcal Serogroups A, C, W-135, Y Conjugate Vaccine When Given as 1 Dose to Healthy Subjects Aged 15-19 Yrs
The purpose of this study is to evaluate the immunogenicity, safety and reactogenicity of one dose of four different formulations of the MenACWY conjugate vaccine when given to healthy subjects aged 15-19 years.
- Trial name
- NCT00196963
- Testing
- Meningococcal (vaccine)
- Where
- Belgium
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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