Clinical trials: Healthy Overweight/Obese
Pregnancy Weight Gain, Postpartum Weight Retention
Pragmatic Randomized Clinical Trial to Limit Weight Gain in Pregnancy and Prevent Obesity
Healthy for Two, Healthy for You (H42/H4U) is an innovative evidence-based pregnancy/postpartum health coach intervention that is remotely-delivered (phone coaching using motivational interviewing, web-based platform, mobile…
- Conditions
- Pregnancy Weight Gain, Postpartum Weight Retention, Childhood Obesity, Gestational Diabetes
- Trial name
- H42/H4U (NCT04724330)
- Testing
- Healthy for Two/Healthy for You
- Where
- United States
- Volunteers
- 534 people
- Sponsor
- Johns Hopkins University
Healthy
Pharmacokinetics of Voriconazole in Obese Subjects
Obese subjects may require a higher fixed oral maintenance dosing regimen of voriconazole compared to normal weight subjects to achieve comparable plasma exposures. The current study is designed to address this issue.
- Trial name
- NCT01030653
- Testing
- Voriconazole low dose, Voriconazole high dose
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Manjunath Prakash Pai
Healthy, Obese
Exercise Regulation of Human Adipose Tissue
The purpose of this study is to determine whether exercise training leads to changes in the white adipose tissue that are beneficial to the body's regulation of sugar and body weight.
- Conditions
- Healthy, Obese, Diabetes Mellitus, Type 2
- Trial name
- NCT03133156
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Obesity
Research Intervention to Support Healthy Eating and Exercise
The primary aim of this study is to test the efficacy of a behavioral economics intervention for weight loss in adults from economically disadvantaged backgrounds.
- Trial name
- RISE (NCT04353258)
- Testing
- Behavioral Economics intervention (BE mHealth), Standard mHealth intervention (mHealth)
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- University of Connecticut
Obesity, Healthy
Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety Phenotype
The purpose of this research is to study the effect of the study drug (a conjugated bile acid dietary supplement) or placebo on cell function, hormones and body weight.
- Trial name
- NCT05314374
- Testing
- Ileocolonic-release conjugated bile acid
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight, Obesity
A Study to Evaluate How VI-0521 Affect Psychomotor Performance in Healthy Overweight and Obese Subjects.
The purpose of this study is to determine how VI-0521 affect speed and reaction time on specific tasks that require eye and hand coordination, compared to placebo.
- Trial name
- NCT00806260
- Testing
- VI-0521, Alcohol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Weight Loss, Diet Modification
Helping Moms to be Healthy After Baby
Low-income and minority women are at increased risk for postpartum weight retention (i.e. retaining weight after pregnancy) and consequent persistent obesity.
- Conditions
- Weight Loss, Diet Modification, Obesity
- Trial name
- NCT03257657
- Testing
- Observation Group participants, Lifestyle group participants
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity; Rurality
Feasibility Trial of the iAMHealthy Intervention
This research study is being done to find out which of 2 ways works best to get rural participants interested in joining a research study about children who weigh more than is considered healthy.
- Trial name
- iAmHealthy (NCT04142034)
- Testing
- the iAmHealthy Behavioral Intervention, Newsletter only arm, Consecutive Recruitment
- Where
- 4 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
Obesity
Healthy Me: A Program for Older Women
The first phase of the study is a feasibility survey of eligible participants, completed prior to initiating the intervention. The intervention consists of a 6-month 1:1 randomized trial with a waitlist control that recruits 120…
- Trial name
- NCT03843190
- Testing
- Take of Pounds Sensibly (TOPS), Waitlist Control
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Duke University
Overweight, Obesity
Study of a Healthy Lifestyle Intervention for Deaf Adults Who Are Overweight or Obese
The purpose of the Deaf Weight Wise study is to test a 16 week, evidence-based, comprehensive program to change obesity-related health behaviors in Deaf people who use American Sign Language (ASL) as their primary language.
- Trial name
- DWW (NCT01452269)
- Testing
- Deaf Weight Wise program
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Obesity Prevention
A Web-Based Healthy Living Training for Promotores
The goal of this clinical trial is to test a new web-based promotora de salud/ community health worker (CHW) training. This training is designed to provide CHWs with the knowledge and skills to effectively implement a healthy…
- Trial name
- NCT06627439
- Testing
- Comadres Saludables, Control
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- ISA Associates, Inc.
Healthy Obesity, Metabolically, Appetite Regulation
Colonic Propionate, Appetite, and Weight Loss
The current protocol aims to investigate the impact of the propionate ester in conjugation with restricted diet on appetite and weight loss.
- Trial name
- ProAp (NCT03322514)
- Testing
- Inulin-Propionate Esters, Inulin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity
A First-Time-in-Human Study to Assess the Safety and Tolerability of PP 1420 in Healthy Subjects
When humans eat, the bowels naturally secrete chemicals into the bloodstream which make people feel full and which stop eating. One of these chemicals is known as "Pancreatic Polypeptide" (PP).
- Trial name
- NCT01052493
- Testing
- PP 1420
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Overweight
Mobile Attention Retraining in Overweight Female Adolescents
Background: People are constantly exposed to unhealthy foods. Some studies of adults show that training attention away from unhealthy foods might reduce overeating.
- Conditions
- Obesity, Overweight, Binge Eating, Healthy Volunteers
- Trial name
- NCT02977403
- Testing
- Attention Bias Retraining
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diabetes Mellitus, Hyperglycemia
Intervening in Diabetes With Healthy Eating, Activity, and Linkages To Healthcare - The I-D-HEALTH Study
The purpose of this study is to compare ways of giving advice and providing support to improve diet and physical activity in adult primary care patients with elevated body mass index and dysglycemia.
- Conditions
- Diabetes Mellitus, Hyperglycemia, Obesity, Glucose Metabolism Disorders
- Trial name
- I-D-HEALTH (NCT01435603)
- Testing
- Standard Lifestyle Advice, Advice Plus Lifestyle Intervention
- Where
- 2 sites in United States
- Volunteers
- 331 people
- Sponsor
- Northwestern University
Overweight, Obesity
A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight Range
This study will look at how the investigational dose of semaglutide works in helping people with excess body weight, to lose weight.
- Trial name
- STEP12 (NCT06041217)
- Testing
- Semaglutide
- Where
- 21 sites in China, Taiwan
- Volunteers
- 242 people
- Sponsor
- Novo Nordisk A/S
Healthy, Obesity
Mitochondrial Function in Circulating Cells and Muscle Tissue
The main goal of this project is to determine whether mitochondrial function in circulating cells is related to that measured in the muscle fibers of the same subjects.
- Conditions
- Healthy, Obesity, Insulin Sensitivity, Women
- Trial name
- MitoWomen (NCT02700698)
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Obesity
The Healthy Weigh Study
This study will evaluate the comparative effectiveness of behavioral economic financial incentives and environmental strategies, separately and together, in achieving initial weight loss and maintenance of weight loss, in obese…
- Trial name
- NCT02878343
- Testing
- Incentives, Environmental strategies
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity
Childcare Healthy Beverage Access, Food and Beverage Intake, and Obesity
Interventions that promote water consumption in place of sugar-sweetened beverages have shown promise for preventing childhood obesity in schoolchildren.
- Trial name
- NCT05112185
- Testing
- Healthy Drinks, Healthy Futures
- Where
- United States
- Volunteers
- 1,034 people
- Sponsor
- Stanford University
Obesity, Adolescent, Health Behavior
Health Literacy and Obesogenic Behaviors
The prevalence of adolescent behaviors that can lead to obesity are alarming, and reduced life expectancy is the future of America's youth if behavioral changes are not implemented to improve health and reduce the obesity burden.
- Conditions
- Obesity, Adolescent, Health Behavior, Health Knowledge, Attitudes, Practice, Diet, Healthy
- Trial name
- HL-Squared (NCT04252677)
- Testing
- Obesity Prevention, Health Literacy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health