Clinical trials: Healthy Participants, open to volunteers
Healthy Adult
Data-driven Rural Interventions for Vitality and Endurance Pilot Study
The study aims to explore whether data driven, personalized wellness interventions-based on integrated genomic, clinical, behavioral, and functional data- are feasible in a rural facing setting and can produce measurable…
- Trial name
- DRIVE (NCT07872995)
- Testing
- Data-driven lifestyle coaching
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McLaughlin Research Institute for Biomedical Sciences, Inc.
Spinal Cord Injury (=3 Years), Traumatic Brain Injury (TBI) Patients
Evaluation of a Voice-Activated Call Light System for Clients With Limited Upper-Extremity Mobility
The goal of this study is to evaluate whether a voice-activated call light system enables people in a rehabilitation facility who have limited use of their arms and hands to call for help more independently and reliably than with…
- Conditions
- Spinal Cord Injury (=3 Years), Traumatic Brain Injury (TBI) Patients, Healthy Adult Participants
- Trial name
- NCT07873151
- Testing
- voice-activated call light
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Quality Living, Inc.
Healthy Adult Participants
Neuroanatomically Informed fMRI Neurofeedback in Healthy Adults
This study will test and refine a type of brain training called functional magnetic resonance imaging (fMRI) neurofeedback in healthy adults.
- Trial name
- NCT07873710
- Testing
- Functional Connectivity fMRI Neurofeedback, ROI-Activity fMRI Neurofeedback
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Healthy Volunteers
Cytapheresis of Volunteer Donors
Background: National Institute on Aging researchers are looking at studies that require large numbers of white blood cells for lab use. Standard blood samples do not provide enough white blood cells for these studies.
- Trial name
- NCT00104325
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Healthy Donors
Collection and Distribution of Samples From Healthy Donors for In Vitro Research at the NCI-Frederick
Background -NCI-Frederick scientists performing in vitro studies involving human specimens have a need for a reliable and consistent source of samples which protects the donor from research risks.
- Trial name
- NCT00339911
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy Volunteers
Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers
The Hematology Branch of the National Heart, Lung, and Blood Institute is doing a variety of laboratory research experiments that require blood and tissue samples from healthy volunteers.
- Trial name
- NCT00442195
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy Volunteers, Non-Healthy/Non-Frail
Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)
Background: Biomarkers are substances in people's blood and tissues. They help researchers understand diseases and signs of aging.
- Conditions
- Healthy Volunteers, Non-Healthy/Non-Frail, Frail
- Trial name
- NCT02339012
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Obesity, Eating Behaviors
Children s Growth and Behavior Study
Background: Studies show that many factors affect children's eating behavior and health. These include sleep, mood, thinking skills, and genetics.
- Conditions
- Obesity, Eating Behaviors, Healthy Volunteers
- Trial name
- NCT02390765
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Neuromuscular Diseases, Healthy Volunteers
Non-Invasive Respiratory Monitor
This study will clinically evaluate a newly developed respiratory monitor - pneuRIP. The pneuRIP uses Respiratory Inductance Plethysmography (RIP) bands to measure key breathing indices non-invasively.
- Trial name
- NCT02851043
- Testing
- pneuRIP (breathing with resistance), Respitrace system (Carefusion) (breathing without resistance)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Healthy Volunteers, Overweight
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)
Background: Artificial sweeteners like sucralose are found in many foods and drinks. Sucralose might affect hormones and cause health changes.
- Trial name
- NCT03407079
- Testing
- Sucralose
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Kidney Stone, Kidney Calculi
Gut Oxalate Absorption in Calcium Oxalate Stone Disease
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased absorption of dietary oxalate, which would lead to increased urinary excretion of oxalate.
- Conditions
- Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate
- Trial name
- NCT06331546
- Testing
- Low-oxalate diet, High-oxalate diet, soluble oxalate gut absorption test
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy
Pulse Revolution: Enhancing Metabolic Health Through the Power of Processed Chickpeas
The purpose of this research is to test how processing can affect how one's body uses the nutrients in that food. For this study the researchers are examining how making different food products out of chickpeas, such as hummus or…
- Trial name
- NCT06758869
- Testing
- Control, Whole Chickpeas, Puréed Chickpeas
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Healthy, Hepatic Impairment
A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems
This study is open to adults aged between 18 and 80 years of age with a body mass index (BMI) of 18.5 to 42 kg/m². People with or without liver problems can take part in the study.
- Trial name
- NCT07023354
- Testing
- BI 1291583
- Where
- 4 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteers
A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants
The purpose of this study is to evaluate the pharmacokinetics (PK) of xanomeline following administration of KarXT in CYP2D6 normal/extensive, intermediate, poor, and ultrarapid metabolizers.
- Trial name
- NCT07204418
- Testing
- Xanomeline/ Trospium Chloride
- Where
- 3 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Healthy Participants
A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants
The purpose of this study is to assess the safety and tolerability of AZD3974 and characterize the pharmacokinetics (PK) of AZD3974 following oral administration to healthy participants, including participants of Japanese and…
- Trial name
- NCT07290283
- Testing
- AZD3974
- Where
- 2 sites in United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Individuals
Making Meals With Pulses
The goal for this study is to determine how Americans use beans, peas, and lentils (also called pulses) as part of a meal. The researchers will investigate food choices when getting a meal or dish ready that is made of more than…
- Trial name
- NCT07451119
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Healthy Participants, Obesity
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
The purpose of the study is to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD1043 following single and multiple ascending doses in healthy adult participants living with overweight and/or…
- Trial name
- NCT07511205
- Testing
- AZD1043
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Adult
Bioequivalence Study of Ferric Carboxymaltose Injection in Healthy Chinese Participants Under Fasting Conditions
The goal of this clinical trial is to compare the pharmacokinetic profile of the developed drug product and reference product in healthy participants under fasting condition.
- Trial name
- NCT07606105
- Testing
- Ferric Carboxymaltose Injection, Ferric Carboxymaltose Injection [Injectafer®]
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sichuan Huiyu Pharmaceutical Co., Ltd
Healthy Volunteer Study, Healthy Adults
A Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma
The purpose of this study is to learn about the safety of a new study medicine called PF-08103402 in healthy adults (do not have disease) and or in adults with mild-to-moderate asthma.
- Conditions
- Healthy Volunteer Study, Healthy Adults, Healthy Participants, Asthma
- Trial name
- NCT07660731
- Testing
- PF-08103402, Midazolam
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Participants, Healthy Adult Subject
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Chronic Study
The goal of this clinical trial is to learn how eating different snack foods affects long term hunger and gut health in healthy adults. The study will be conducted remotely over 7 weeks.
- Conditions
- Healthy Participants, Healthy Adult Subject, Healthy Subjects, Healthy Adult Volunteer
- Trial name
- SMARTEATS-RCT (NCT07782593)
- Testing
- High-fibre plant-based snack bar, Control snack bars
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited