Clinical trials: Healthy Patients
Thyroid Diseases, Healthy Lifestyle
The Effect of Mobile-Based Education on Postoperative Recovery and Quality of Life in Thyroidectomy Patients
Thyroid diseases constitute one of the most common health problems around the world and in our country. In its treatment; Drug therapy, radioactive iodine therapy and surgical treatment can be applied alone or together.
- Conditions
- Thyroid Diseases, Healthy Lifestyle, Thyroid
- Trial name
- NCT06383481
- Testing
- Mobile based education
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ataturk University
Intensive Care Unit, Muscle Strength
Normative Values for Peripheral Muscle Strength in Critical Patients and Healthy Individuals
Muscle strength is an important indicator of overall health and is a factor that has been associated with increased mortality in critical patients.
- Trial name
- HHD-ICU (NCT06296381)
- Where
- 4 sites in Brazil
- Volunteers
- 180 people
- Sponsor
- University of Pernambuco
Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder
Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
The purpose of this study is to investigate how emotional and non-emotional regulation processes differ in EIP patients (with different levels of ADHD symptoms/ADHD-comorbidity) compared to controls.
- Conditions
- Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder, Healthy Controls
- Trial name
- NCT02797873
- Testing
- fMRI - Stroop task, fMRI - MID task, Stop Signal Task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cystic Fibrosis
Evaluation of Sit-to-stand Test in Patients With Cystic Fibrosis and Matched Controls.
Introduction: In recent years, since the discovery of the cystic fibrosis (CF) transmembrane conductance regulator gene in human skeletal muscle, there appears to be growing interest in the measurement of muscle function in CF.
- Trial name
- STS-CF (NCT03524859)
- Where
- Spain
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Coronary Heart Disease, Diabetes Mellitus, Type 2
Arterial Stiffness in Type 2 Diabetic Patients With Severe Periodontitis
Studies were found that a significant relationship between the severe periodontitis and increased CAVI values. While the exact mechanisms linking periodontitis, type 2 diabetes, and cardiovascular disease are not yet fully…
- Conditions
- Coronary Heart Disease, Diabetes Mellitus, Type 2, Periodontitis, Arterial Stiffness
- Trial name
- NCT05866497
- Testing
- clinical periodontal measurements, CAVI measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
IBS, Healthy
Measuring Nerve Activity in Small Human Intestinal Biopsies in IBS (Irritable Bowel Syndrome)
Rectal biopsies from IBS patients or healthy subjects will be taken. Biopsies will be used for: 1. the isolation of submucosal plexus to perform: 1.1 live nerve recordings and Calcium imaging; 1.2 immunohistochemistry; 1.3 mRNA…
- Trial name
- NCT01912313
- Testing
- Rectal biopsies from IBS patients or healthy subjects will be taken during proctoscopy
- Where
- Belgium
- Volunteers
- 99,999,999 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude, Echocardiography
- Trial name
- NCT07804524
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Healthy
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GS-248
This is a First in Human (FIH), double-blinded, parallel-group, randomised, placebo-controlled study designed to evaluate the safety, tolerability, PK and PD of single and multiple ascending oral doses of GS-248 in healthy…
- Trial name
- NCT04036227
- Testing
- GS-248
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gesynta Pharma AB
Mental Health Issue
HELP (HEalthy Lifestyles Project) for Youth With Mental Distress
The goal of this clinical trial is to learn about how healthcare providers can support youths' mental health. The main question[s] it aims to answer are: Do youth (12 to 17 years of age) who engage in the 6-month HELP…
- Trial name
- HELP (NCT06232733)
- Testing
- Healthy Lifestyles Project e-intervention
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- Children's Hospital of Eastern Ontario
Diabetes, Wound Infection
Omadacycline Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis
This study will determine the tissue penetration of the novel tetracycline antibiotic, omadacycline (Nuzyra, Paratek Pharmaceuticals, Inc.), into the extracellular, interstitial fluid of soft tissue in diabetic patients with…
- Conditions
- Diabetes, Wound Infection, Healthy Volunteers
- Trial name
- NCT04144374
- Testing
- Omadacycline, Microdialysis Catheter Insertion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Healthy
Development of an Exoskeleton for Patients' Mobility.
The goal of this clinical trial is to investigate the performance of a state-of-the-art adaptive CPG-based exoskeleton control system (intelligent mode) under a multi-metric analysis (involving three-dimensional gait analysis…
- Trial name
- NCT06513390
- Testing
- Exoskeleton of default mode, Exoskeleton of Intelligent mode
- Where
- Thailand
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Vidyasirimedhi Institute of Science & Technology (VISTEC)
Accumbo Frontal Tract
Accumbofrontal Tract Study in 2 Populations of Patients With Anorexia Nervosa and Obsessional Compulsive Disorder and Healthy Volunteer
Restrictive anorexia nervosa and TOCs are psychiatric diseases which shares a common pathophysiological substrate We hypothesize that anorexia patients and patients with OCD have structural and functional changes in the…
- Trial name
- ACCUMBENS (NCT03496285)
- Testing
- Multimodal MRI with diffusion sequence for anorexia nervosa patient, Multimodal MRI with diffusion sequence for obsessional compulsive disorder patient, Multimodal MRI with diffusion sequence for healthy volunteer
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Female Breast Carcinoma, Healthy Subject
Technology and Health Communication in Improving Health Outcomes in Patients Scheduled for Mammography
This pilot clinical trial studies how well technology and health communication works in improving health outcomes in patients scheduled for mammography screening.
- Trial name
- NCT04290585
- Testing
- Questionnaire Administration, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Healthy
Computerized Risk Assessment in an Employee Population
This is a study to determine whether a computerized risk assessment and focused patient provider interaction can improve health outcomes in an employee population.
- Trial name
- NCT00153335
- Testing
- patient-provider interaction
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Pneumoperitoneum Increases Mean Expiratory Flow Rate
Pneumoperitoneum Increases Mean Expiratory Flow Rate: an Observational Study in Healthy-lung Patients
Upon introducing pneumoperitoneum our research team noticed a reduction in expiration time displayed on the screen of the anesthesia machine.
- Trial name
- NCT06212258
- Testing
- Abdominal Laparascopy
- Where
- Hungary
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Balázs Sütő
Seasonal Allergic Rhinitis, Healthy Subjects
A Pilot Monocenter Study to Assess Cellular and Soluble Biomarkers in Nasal Secretions
Allergic Rhinitis is an inflammatory disease which causes an influx of inflammatory cells and cytokines into the nasal mucosa. These biomarkers can also be found in the nasal secretions.
- Trial name
- NCT00297843
- Testing
- allergen challenge (grass pollen), nasal lavage
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Chronic Pain
The Effects of Water Temperature on the Cold Pressor Test
This current study is intended to be completed under the umbrella of the current GHUCCTS IRB- approved study "Opioid-Induced Hyperalgesia In Prescription Opioid Abusers: Effects of Pregabalin" (Lyrica study) (PRO00000669).
- Trial name
- NCT03083626
- Testing
- Cold pressor test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Cough
Repeat Doses of BAY1902607 in Healthy Males and Proof of Concept in Chronic Cough Patients
The primary objectives of this study: To investigate the safety and tolerability of ascending repeated oral doses of BAY1902607 in healthy subjects (Part 1).
- Trial name
- NCT03535168
- Testing
- BAY1902607, Midazolam
- Where
- 8 sites in Netherlands, United Kingdom
- Volunteers
- 59 people
- Sponsor
- Bayer
Hypertension
First-in-Human Study of VB0004 in Healthy Subjects and to Patients With Mild to Moderate Hypertension With Low Cardiovascular Risk
This will be a single center, Phase I/IB, randomized, double-blind, placebo-controlled, sequential SAD/MAD/FE study, with a patients arm.
- Trial name
- NCT04925050
- Testing
- VB0004
- Where
- 3 sites in Australia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Syneos Health
Pseudoxanthoma Elasticum, Tomography, Optical Coherence
CHOPXE - Analysis of Choriocapillaris Flow Deficits in Patients With Pseudoxanthoma Elasticum
This observational study sets out to compare choriocapillaris flow deficits between healthy control subjects and patients with pseudoxanthoma elasticum.
- Conditions
- Pseudoxanthoma Elasticum, Tomography, Optical Coherence, Retinal Disease
- Trial name
- CHOPXE (NCT07006649)
- Testing
- Opthtalmologic diagnosis tests
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
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