Clinical trials: Healthy Person
HCV Infection
Evaluation of Safety, Tolerability, and Immunogenicity Study of GLS-6150 in Healthy Volunteers and in Persons Previously Treated for Hepatitis C Virus Infection
Hepatitis C virus (HCV) is an enveloped, single strand, positive sense RNA flavivirus. Infection by HCV is typically chronic, although an estimated ~10-20% may spontaneously clear the virus.
- Trial name
- NCT03674125
- Testing
- GLS-6150
- Where
- 2 sites in South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GeneOne Life Science, Inc.
Hepatic Impairment, Healthy, Hepatic Insufficiency
A Study to Learn How the Study Medicine Called Atirmociclib is Handled by the Body in People With Normal Liver Function and Different Levels of Liver Disease
The purpose of this study to understand how the study medicine atirmociclib behaves in the body and how safe it is for people with different levels of liver health.
- Conditions
- Hepatic Impairment, Healthy, Hepatic Insufficiency, Healthy Adults
- Trial name
- NCT07677358
- Testing
- Atirmociclib
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Aging
BACTERIA ISOLATION FROM STOOLS COLLECTED FROM CENTENARIANS PEOPLE
The compositional analysis of commensal bacterial populations collected from a variety of clinical samples has been recently made possible with the availability of Next Generation Sequencing (NGS) technologies.
- Trial name
- BISCOTE (NCT05701371)
- Testing
- Biological samples collection
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bioaster
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction
Comparison of Kinematic Movements Between ACL Deficiency With ACL Reconstruction and Healthy People
Comparison of kinematic movements between patients with anterior cruciate ligament rupture and post-operative patients and normal people using a mobile dynamic X-ray device.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction, Healthy People
- Trial name
- NCT05619393
- Testing
- Mobilie Bi-planar X-ray Imaging system
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wang Joon Ho
Spina Bifida, Cerebral Palsy
Children and Teens in Charge of Their Health
This three year study explores the feasibility and acceptability of conducting a full randomized controlled trial (RCT) of a promising coaching intervention for improving and sustaining physical activity (PA) and healthy dietary…
- Conditions
- Spina Bifida, Cerebral Palsy, Health Behavior
- Trial name
- CATCH (NCT03523806)
- Testing
- Solution-Focused Coaching in Pediatric Rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Healthy Volunteers, Recovery
Effects of Carnipure® Tartrate on Postprandial Endothelial Function and Recovery
Investigation of 4 weeks supplementation with Carnipure® tartrate on endothelial function and parameters of recovery after physical exertion.
- Conditions
- Healthy Volunteers, Recovery, Endothelial Function
- Trial name
- NCT02635594
- Testing
- L-Carnitine
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lonza Ltd.
Diabetes Mellitus, Type 2
Perceived Stress and Negative Thoughts With Biomarkers in People With Type 2 Diabetes Mellitus and Healthy Subjects
The purpose of this study is to determine the effect of measured and induced negative feelings on glucose, tumor necrosis factor alpha, and cortisol levels in healthy participants and participants with type 2 diabetes mellitus.
- Trial name
- NCT04387045
- Testing
- Guilty feelings
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francisco Carlos López Marquez
Healthy
Allicin Bioavailability From Garlic Supplements and Garlic Foods
This study will measure the bioavailability of allicin, the main active compound of garlic, from garlic supplements and garlic foods (raw, cooked, processed) so that supplement manufacturers and clinical investigators know how…
- Trial name
- NCT00874666
- Testing
- crushed garlic clove, garlic powder tablet
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Silliker, Inc.
Functional Constipation, Healthy
Effect of scFOS on Increase in Stool Frequency in Constipated People
The study aims to evaluate the effects of short-chain fructo-oligosaccharides on the frequency and consistency of stools in subjects with functional constipation.
- Trial name
- CONSYST (NCT03707002)
- Testing
- scFOS, Maltodextrin
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Syral
Diabetes, Heart Diseases
Personalised Responses to Dietary Composition Trial
The foods we eat - our diet - can affect whether we develop diseases during our lives, such as diabetes or heart disease. This is because the amount and types of foods we eat can affect our weight, and because different foods are…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- PREDICT (NCT03479866)
- Testing
- Dietary intervention
- Where
- United Kingdom
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Healthy
A Study of Canagliflozin and Metformin Immediate Release (50 mg/500 mg) FDC Tablets in Healthy Volunteers
The purpose of this study is to evaluate the bioequivalence of fixed dose combination (FDC) tablets of canagliflozin and metformin immediate release (IR) in comparison with the individual components of the FDC tablets…
- Trial name
- NCT01508195
- Testing
- Canagliflozin tablets, Metformin IR tablets, Canagliflozin/metformin IR FDC tablets
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Neoplasms
Salivary Cytokines as Biomarker for Oral Health
Oral complications during and after cancer treatment are common. A key role in maintaining oral health plays saliva. In the last decade numerous studies have investigated immunological biomarkers such as cytokines in saliva…
- Trial name
- Cytosal (NCT02807519)
- Testing
- collection of salivary cytokines
- Where
- 3 sites in Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Overweight, Obesity
A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight Range
This study will look at how the investigational dose of semaglutide works in helping people with excess body weight, to lose weight.
- Trial name
- STEP12 (NCT06041217)
- Testing
- Semaglutide
- Where
- 21 sites in China, Taiwan
- Volunteers
- 242 people
- Sponsor
- Novo Nordisk A/S
Epilepsy and Neuropathic Pain
Evaluation of Individual Bioequivalence of Gabasandoz® Relative to Neurontin® in Healthy Volunteers
The NO SWITCH list is based on the hypothesis that the pharmacokinetic differences between different batches of one medicines are smaller than the pharmacokinetic differences between two medicines (from a different manufacturer…
- Trial name
- DRUG13-GABA (NCT01821235)
- Testing
- Neurontin® (gabapentin) batch A, Neurontin® (gabapentin) batch B, Gabasandoz® (gabapentin) batch A
- Where
- Belgium
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Healthy Test Persons, Mild Cognitive Impairment
Identification of Predictors for Early Cognitive Decline in Men
The research program explores how aging influences brain function in test-persons from a Danish birth cohort of men born in 1953.
- Conditions
- Healthy Test Persons, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03290040
- Where
- Denmark
- Volunteers
- 564 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Old Age; Debility, Loneliness
The Effect of Home Visit Supported Nursing Education Program on Some Parameters in Elderly People Living Alone at Home
It is aimed to develop healthy lifestyle behaviors of elderly people living alone at home, reduce their loneliness levels and increase their social support capacity.The research was planned as a quasi-experimental research.
- Conditions
- Old Age; Debility, Loneliness, Healthy Lifestyle
- Trial name
- NCT06517615
- Testing
- Home Visit Supported Nursing Training Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Liver Diseases, Healthy
A Study to Test How BI 690517 is Taken up in the Body of People With and Without Liver Problems
The main objective of this trial is to assess the effect of mild and moderate hepatic impairment (Child-Pugh classification A and B) on the pharmacokinetics, safety, and tolerability of BI 690517 in comparison with a control…
- Trial name
- NCT05731908
- Testing
- BI 690517
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Parkinson Disease, Healthy Adult
Multiple Sessions of Transcranial Direct Current Stimulation in People With Parkinson's Disease
Parkinson's disease (PD) affects approximately 1 million people in the US, with annual health care costs approaching $11 billion. PD results from a loss of dopamine-producing cells in the brain.
- Trial name
- NCT04762823
- Testing
- Cerebellar transcranial direct current stimulation at 4 mA
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Healthy
Normative State and Variation in Growth, Hematology, Hydration, Oxidation, Infection, Inflammation, Guatemalan Children
This study will provide the researchers with an opportunity for the investigation of the biomarkers and different human biology component variable interactions in children; information that can generate new correlations between…
- Trial name
- NCT02203890
- Where
- Guatemala
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- María José Soto
Coronavirus
Recombinant New Coronavirus Vaccine (CHO Cells) to Prevent SARS-CoV-2 Phase I Clinical Trial (≥60 Years Old)
Popular topic: Phase I clinical trial of recombinant new coronavirus vaccine (CHO cell) (≥60 years old) Research purpose: Main purpose: To evaluate the safety and tolerability of different doses of recombinant new coronavirus…
- Trial name
- NCT04550351
- Testing
- Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cell) low-dose group, Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cells) high-dose group
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.