Clinical trials: Healthy Volunteer Subjects
Burns
Volume Kinetics for Hyperoncotic Albumin in Burn Patients as Well as for Healthy Subjects
Treatment with colloidal solutions has during long time been a cornerstone within intensive care. Lately, doubts have been raised about synthetic colloids, and the natural albumin has been used more and more.
- Trial name
- VAB (NCT02952378)
- Testing
- Albumins
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Rabies (Healthy Volunteers)
A Phase II Trial of a Recombinant Human Anti-Rabies Virus Monoclonal Antibody
A Phase II, Single-Center, Randomized, Blinded, Controlled Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Recombinant Human Anti-Rabies Virus Monoclonal Antibody Injection in Healthy Subjects
- Trial name
- NCT07445815
- Testing
- Recombinant Human Rabies Virus Monoclonal Antibody Injection, Human Rabies Immunoglobulin (HRIG), Rabies Vaccine
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lanzhou Institute of Biological Products Co., Ltd
In Development for Cystic Fibrosis
Study of VX-770 in Subjects With Moderate Hepatic Impairment and in Matched Healthy Subjects
The purpose of this study is to investigate the pharmacokinetics and safety of a single dose of VX-770 in subjects with moderate hepatic impairment.
- Trial name
- NCT01208285
- Testing
- VX-770
- Where
- 3 sites in Czechia, Slovakia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vertex Pharmaceuticals Incorporated
Cancer
A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of AB801 in Healthy Volunteers
The primary purpose of this study is to determine the safety and tolerability of AB801, and to understand the pharmacokinetic (PK) profile of AB801 when taken as a capsule and tablet in healthy volunteers.
- Trial name
- ARC-26 (NCT06004921)
- Testing
- AB801
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Arcus Biosciences, Inc.
Healthy
Evaluation and Validation of Metabolic Markers for the Assessment of CYP3A Activity and Prediction of DDI
Evaluation and validation of metabolic markers for the assessment of CYP3A activity and prediction of drug-drug interaction in Korean healthy subjects.
- Trial name
- CYP3A_weak (NCT02328443)
- Testing
- Midazolam, itraconazole, rifampicin
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Healthy Subjects
An Open-label Trial to Evaluate Mass Balance of Tavapadon at Steady State in Healthy Subjects
The purpose of this trial is to determine the absorption, metabolism, and excretion (AME) of [14C] tavapadon.
- Trial name
- NCT04241393
- Testing
- Tavapadon tablet, Tavapadon [14C] suspension
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cerevel Therapeutics, LLC
Cardiovascular
AMG 529 First in Human Study
A study to assess the safety and tolerability of AMG 529 following single, ascending doses administered subcutaneously (SC) or intravenously (IV) in healthy adults.
- Trial name
- NCT03170193
- Testing
- AMG 529
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Amgen
Healthy
A Relative Bioavailability Study of 200mg/5 mL Azithromycin Oral Suspension Under Fasting Conditions
The study will compare the relative bioavailability (rate and extent of absorption) of 200 mg/5 mL Azithromycin oral suspension manufactured by TEVA Pharmaceutical Industries Ltd.; distributed by TEVA Pharmaceuticals USA with…
- Trial name
- NCT00830206
- Testing
- Azithromycin, Zithromax®
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Heartburn
A Study to Compare Omeprazole Administered as Zegerid® Powder and as Prilosec® Capsule in Healthy Participants (P08050)(CL2010-12)
This study compares the bioequivalence of omeprazole administered as either Zegerid® powder for oral suspension 20 mg or as Prilosec 40 mg capsule to healthy participants.
- Trial name
- NCT01337804
- Testing
- omeprazole/sodium bicarbonate, omeprazole magnesium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bayer
Malaria
Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects
This was a randomized, subject and investigator-blinded, placebo-controlled, single and multiple ascending intravenous (iv) dose study in healthy subjects to assess the safety and tolerability of KAE609 given in the vein.
- Trial name
- NCT04321252
- Testing
- KAE609
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Healthy Volunteer
A Study to Assess the Relative Bioavailability of Gilteritinib Following a Single Dose of Gilteritinib Mini-tablet Oral Suspension and Gilteritinib Mini-tablets Compared to a Single Dose of Gilteritinib Tablet in Healthy Subjects
The purpose of this study is to assess the relative bioavailability as well as the safety and tolerability of single doses of gilteritinib mini-tablets oral suspension and gilteritinib mini tablets compared to gilteritinib…
- Trial name
- NCT03964038
- Testing
- gilteritinib, gilteritinib mini tablet
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Healthy Volunteers
Pharmacokinetics of a Fixed Dose Combination of Canagliflozin/Metformin Coadministered With Food
The purpose of this study is to assess the effect of coadministration of a high-fat meal on the oral bioavailability of a fixed dose combination of Canagliflozin/extended release Metformin (CANA/MET XR) tablet, containing 150 mg…
- Trial name
- NCT02039258
- Testing
- CANA/MET XR FDC
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Diabetes Mellitus
Study of Harmine in Healthy Subjects
The present study is a phase 1 dose escalation study of harmine in healthy volunteers. The primary goal of the trial is to determine the maximum tolerated dose of harmine.
- Trial name
- NCT05526430
- Testing
- Harmine Hydrochloride Capsules
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- James Murrough
Symptomatic Neurogenic Orthostatic Hypertension, nOH
Thorough QT Study to Evaluate Ampreloxetine in Healthy Subjects
A double-blind study to characterize the effect of ampreloxetine on cardiac repolarization in healthy subjects.
- Trial name
- NCT04688632
- Testing
- Ampreloxetine <Dose A>, Ampreloxetine <Dose B>, Moxifloxacin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Healthy Volunteers
A Study of Evacetrapib in Healthy Female Participants
The purpose of this study is to evaluate the effects of evacetrapib on oral contraceptives (Ortho-Cyclen®) when given to healthy female participants.
- Trial name
- NCT01746732
- Testing
- Ortho-Cyclen, Evacetrapib
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Drug Safety
Ascending Single-Dose and Multiple-Dose Study to Evaluate RJ4287 in Healthy Subjects
A Randomized Study of RJ4287 Drug to Evaluate the Safety, Tolerability, Pharmacokinetics and Food-effect of Single and Multiple Doses in Healthy Volunteers
- Trial name
- NCT05921006
- Testing
- RJ4287
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Nanjing Ruijie Pharma Co., Ltd.
Healthy Subjects (HS)
Reactive Balance Training in Augmented Reality for Older Adults
This is a single-blinded study. The participants will be equally randomized to either the reactive balance training with augmented reality (RBT+AR) group or the control (treadmill walking) group.
- Trial name
- NCT07860619
- Testing
- Reactive balance training with augmented reality group, Treadmill walking
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Pharyngitis Acute, Gingivitis
Salivary Drug Concentration Exploratory Study of Cetylpyridinium Chloride Buccal Tablets
The study is a single-arm, open-label study to explore the salivary concentration of Cetylpyridinium Chloride Buccal Tablets after single-dose administration in Healthy Subjects
- Trial name
- NCT05802628
- Testing
- Cetylpyridinium Chloride Buccal Tablets
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Healthy Subjects
Observational Study of the Preventive Trial With HIV-1 Tat Protein
The results of the Phase I Safety and Immunogenicity Trial of Recombinant HIV-1 Tat (ISS P-001 and ISS T-001) indicate that the vaccine based on the recombinant Tat protein is safe, well tolerated and immunogenic.
- Trial name
- ISS OBS P-001 (NCT01024764)
- Where
- 3 sites in Italy
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Istituto Superiore di Sanità
Healthy Subjects, Pharmacokinetics of ASP3652
A Study to Assess the Pharmacokinetics, Metabolism and Excretion Routes of ASP3652 in Man, After Administration of 14C Radio Labeled ASP3652
This study measures how much of the trial drug enters the body and how long it takes for the body to remove it via the feces and urine.
- Trial name
- NCT02046798
- Testing
- ASP3652
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.