Clinical trials: Healthy Volunteer Subjects
Healthy
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Inhaled XQ-001 in Healthy Subjects
The primary study objective is to evaluate the safety and tolerability of XQ-001 for inhalation after single and multiple nebulized inhalation administration in healthy Chinese adult subjects.
- Trial name
- NCT06918366
- Testing
- Part A - single rising dose 1, Part A - single rising dose 2, Part A - single rising dose 3
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Brilliant Inspiration Biotherapeutics
Healthy
Single Ascending Dose Study of WAL0921 in Healthy Subjects
This is a randomized, double-blind, placebo-controlled, single ascending dose study to evaluate the safety, pharmacokinetics, and pharmacodynamics of WAL0921 in healthy subjects.
- Trial name
- NCT05891366
- Testing
- WAL0921
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Walden Biosciences
Anticoagulant
A Single Dose Bioequivalence Study of WD-1602 Versus Pradaxa® in Healthy Subjects Under Fed Condition
This study will be a single-center, randomized, single-dose, open-label, two-treatment, two-period, two-sequence crossover bioequivalence study to compare the rate and extent of absorption of WD-1602 granule formulation (WD…
- Trial name
- NCT04592822
- Testing
- WD-1602, Pradaxa®
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hong Kong WD Pharmaceutical Co., Limited
Health Volunteer
A Single and Multiple Ascending Doses Study to Evaluate the Safety and Pharmacokinetics of RBD5044
This is a randomized, double-blind, placebo-controlled phase I study to evaluate the safety, tolerability, PK profiles and PD effect of single and multiple ascending doses of subcutaneously administered RBD5044 in healthy…
- Trial name
- NCT05539651
- Testing
- RBD5044
- Where
- Australia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Suzhou Ribo Life Science Co. Ltd.
Healthy Volunteers
Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants
The primary objectives of this study are to evaluate the effect of AMG 510 on the pharmacokinetics (PK) of metformin in healthy participants and to evaluate the effect of metformin on the PK of AMG 510 in healthy participants.
- Trial name
- NCT05550129
- Testing
- AMG 510, Metformin
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Amgen
Healthy Subjects
Single Ascending Dose Study of TD-1439 in Healthy Subjects
Single ascending dose study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of TD-1439 in healthy subjects
- Trial name
- NCT02903095
- Testing
- TD-1439
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Non-Alcoholic Fatty Liver Disease
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BAR 502 in Healthy Subjects
This is a prospective, single-center, randomized, double-blind, placebo-controlled, single-ascending dose (SAD) phase 1 study to evaluate the safety and tolerability of single-ascending doses of BAR 502 in healthy male and female…
- Trial name
- NCT05203367
- Testing
- BAR502
- Where
- Portugal
- Volunteers
- healthy volunteers welcome
- Sponsor
- BAR Pharmaceuticals s.r.l.
Asthma, COPD
Evaluation of 3D Magnetic Resonance Spirometry: Comparison with Spirometry in Healthy Subjects and Patients with Respiratory Pathologies (asthma, COPD, Bilateral Lung Transplant)
Spirometry is now the gold standard technique for assessing lung function in humans. From the shape of a flow-volume curve measured while the patient, trained by the practitioner, performs forced breaths, the forced vital…
- Conditions
- Asthma, COPD, BOS
- Trial name
- gb-Spiro3D (NCT05724745)
- Testing
- 1. Standard spirometry, 2. 3D dynamic lung MRI at UTE in prone and supine positions, 3. Reversibility test with salbutamol
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Healthy Subjects
Microvascular Sex and Age-related Day-to-day Variability in Healthy Subjects
The goal of this observational study is to learn more about the microcirculation in the skin by examining sex and age-related day-to-day variability in healthy subjects.
- Trial name
- NCT06009939
- Testing
- Occlusion of the circulation in the arm and foot
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vårdcentralen Åby
Healthy Volunteers
Evaluation of the Relative Bioavailability and Food Effect of GDC-9545 in Healthy Females of Non-Childbearing Potential
This study will be an open-label, randomized, three-period, six-sequence crossover study of GDC-9545 administered to healthy females of non-childbearing potential to determine the relative bioavailability of the Phase 3 capsule…
- Trial name
- NCT04274075
- Testing
- GDC-9545 Tablet, Fasted: Treatment A, GDC-9545 Capsule, Fasted: Treatment B, GDC-9545 Capsule, Fed: Treatment C
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Cystic Fibrosis
Drug-Drug Interaction Study of VX-809 and VX-770 in Healthy Subjects
The purpose of this study is to assess the pharmacokinetics and safety of co-administration of VX-770 and VX-809 in healthy adults.
- Trial name
- NCT00966602
- Testing
- VX-809, VX-770, VX-809 & VX-770
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vertex Pharmaceuticals Incorporated
Type 2 Diabetes
A Drug Interaction Study of SY-004 Capsules in Healthy Subjects
A single center, open-label, single sequence study was conducted to evaluate the potential drug interaction of CYP3A4 inducer rifampicin with SY-004 capsules in healthy subjects
- Trial name
- NCT04907019
- Testing
- rifampicin，SY-004
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Suzhou Yabao Pharmaceutical R&D Co., Ltd.
Healthy
DBM-1152A Inhalation Solution in Healthy Volunteers
This is a single-center, randomized, double-blind, placebo-controlled Phase 1b study to evaluate the safety, tolerability, and pharmacokinetics (PK) of multiple-dose DBM-1152A inhalation solution in healthy Chinese adults.
- Trial name
- NCT07439419
- Testing
- DBM-1152A
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Joincare Pharmaceutical Group Industry Co., Ltd
Anthrax
Single Dose, Weight-Based, Dose-Escalation Study With Intravenous ETI-204 in Adult Volunteers
This study will determine the safety and PK of a single IV dose of ETI-204 in subjects 18 to 65 years of age. Three cohorts will be studied with subjects receiving ETI-204.
- Trial name
- NCT01453907
- Testing
- ETI-204, "Anthim"
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Elusys Therapeutics
Healthy
Clarithromycin 500 mg Extended Release Tablets Under Fasting Conditions
The objective of this study is to compare the relative bioequivalence of a test clarithromycin extended release formulation to an equivalent oral dose of the commercially available extended release clarithromycin in a test…
- Trial name
- NCT00840411
- Testing
- Clarithromycin ER 500 mg tablets, BIAXIN® XL 500 mg tablets
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Healthy Subjects
Safety Study of BMS-986165 in Healthy Subjects and to Treat Psoriasis
The purpose of this study is to establish if BMS-986165 is safe and effective at treating autoimmune diseases. BMS-986165 which has shown some promise in preclinical studies for inhibiting autoimmune conditions.
- Trial name
- NCT02534636
- Testing
- BMS-986165, Interferon alpha-2a recombinant, Famotidine
- Where
- Australia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Fatigue
Tolerability and Benefit of IQP-AS-121 on Fatigue and Mental Alertness
The purpose of this study is to evaluate the tolerability and benefit of IQP-AS-121 on reducing fatigue and tiredness and to improve mental alertness.
- Trial name
- NCT02871271
- Testing
- IQP-AS-121
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- InQpharm Group
Fasciae (Anatomy)--Inflammation
Self-Myofascial Release in the Posterior Myofascial Chain
The study investigates the relation between different segments of the posterior myofascial chain of the human body. The intervention consists on apply self-myofascial release with a foam roller in one of the segments of the…
- Trial name
- NCT03521544
- Testing
- Self-myofascial release
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Healthy
BIIB033 Single Ascending Dose Study in Healthy Volunteer Subjects
The primary objective of the study is to evaluate the safety and tolerability of single dose of BIIB033 administered to healthy adult volunteers.
- Trial name
- NCT01052506
- Testing
- BIIB033
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Biogen
Influenza, Human
A Study to Evaluate the Efficacy and Safety of GC3110A in Healthy Subjects Aged 65 Years and Older
The purpose of this study is to evaluate immunological efficacy and safety of GC3110A among healthy adults over 65 years of age.
- Trial name
- NCT02917304
- Testing
- GC3110A vaccine
- Where
- 10 sites in South Korea
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Green Cross Corporation
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