Clinical trials: Healthy Volunteers.
HIV Infection, Infection, Human Immunodeficiency Virus
A Study To Evaluate Formulations And Food Effect On GSK364735 In Healthy Subjects.
This study is a two-part study. Part one is designed to see how different formulations of GSK364735 are absorbed in the body and To see how food affects how GSK364735 is absorbed in the body.
- Trial name
- NCT00386347
- Testing
- GSK364735 oral solution and oral tablets
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Participants
A Study to Evaluate the PK/PD and Safety of KL0011034 Injection in Healthy Non-Elderly and Elderly Trial Participants
To evaluate the pharmacokinetic characteristics of a single intravenous injection of KL0011034 injection in healthy non-elderly and elderly trial participants.
- Trial name
- NCT07913048
- Testing
- KL0011034 injection
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hunan Kelun Pharmaceutical Co., Ltd.
Healthy Volunteers
Bioequivalence Study of V0057 Versus a Reference Formulation After Single Administration in Healthy Male Subjects
The purpose of this study is to evaluate the bioequivalence (comparison of the rate and extent of the active substance into the body following single administration of the drugs) between the test product V0057 and a reference…
- Trial name
- NCT01861626
- Testing
- V0057 - A mg, Isotretinoin
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermatology
Benign Prostatic Hyperplasia
A Study to Evaluate the Safety and Pharmacokinetics of AD-116 and AD-1161 in Healthy Adult Male Subjects
A Study to Evaluate the Safety and Pharmacokinetics of AD-116 and AD-1161 Under Fed Conditions in Healthy Adult Male Subjects
- Trial name
- NCT07444385
- Testing
- AD-116, AD-1161
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Healthy Volunteer
PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects
An open label, multiple-dose, phase 1 clinical trial to evaluate pharmacokinetics, pharmacodynamics, safety and tolerability of PHP-201 topical eye drop in Korean and Japanese healthy subjects
- Trial name
- NCT03586908
- Testing
- PHP-201 0.5% ophthalmic solution (topical eye drop)
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- pH Pharma
Hypertension
Comparative Bioavailability Study of Eplerenone 50 mg Tablets Under Fasting Conditions
The purpose of this study is to demonstrate the relative bioequivalence of Eplerenone 50 mg ER Tablets under fasting conditions.
- Trial name
- NCT00865176
- Testing
- Eplerenone 50 mg Tablets Sandoz Inc., USA, Inspra 50 mg Tablets GD Searle LLC, USA
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sandoz
Inflammatory Disease
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food Effect of AMG 357 in Healthy Subjects
Study to evaluate the safety, tolerability, PK, PD, and food effect of AMG 357 in healthy subjects
- Trial name
- NCT01695876
- Testing
- AMG 357
- Where
- 3 sites in New Zealand
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Amgen
Healthy Volunteer
Phase I Study of the Safety, Tolerability, PK & PD of Lomitapide in Japanese and Caucasian Subjects With Elevated LDL-C
This is a randomized, double-blind, placebo-controlled, single ascending dose (SAD) and multiple ascending dose (MAD) study of orally administered lomitapide in healthy male Japanese and Caucasian subjects with elevated LDL-C.
- Trial name
- NCT01760187
- Testing
- lomitapide
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Aegerion Pharmaceuticals, Inc.
Healthy
Phase 1 PK, Bioavailability, Safety Study of Clonidine MBT w Catapres in Healthy Volunteers
The purpose of this study is to determine the pharmacokinetic dose proportionality of 50 μg and 100 μg Clonidine and comparative bioavailability of clonidine with that from the Reference drug, Catapres® 100 μg oral tablets…
- Trial name
- NCT02548806
- Testing
- Clonidine MBT 50µg, Clonidine MBT 100µg, Catapres 100μg
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valerio Therapeutics
Healthy Volunteers
A Phase 1 Pharmacokinetic Study of Single-Ascending Doses of Intravenous Nafithromycin in Healthy Adult Subjects
This is a Phase 1, randomized, double-blind, single-center, placebo-controlled, sequential-cohort study in at least 60 healthy adult male and female subjects.
- Trial name
- NCT02770404
- Testing
- Nafithromycin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wockhardt
Healthy Volunteers
A Study To Investigate The Effect Of Food On The Pharmacokinetics Of PH-797804
The purpose of this study is to investigate the effect of food on the time course of PH-797804 concentration in the blood following dosing by oral immediate release tablet formulation.
- Trial name
- NCT01479647
- Testing
- PH-797804
- Where
- Singapore
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Single and Multiple Ascending Dose Study for NKTR-118 and Cross-over Study to Investigate the Effect of Food for NKTR-118 in Japanese Healthy Subjects
The purpose of this study is to evaluate the safety and tolerability of NKTR-118 with healthy subjects.
- Trial name
- Japan SMAD (NCT01318655)
- Testing
- NKTR-118
- Where
- Japan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Test Catheter Pilot Study in Healthy Volunteers
The purpose of this study is to evaluate the safety of an intermittent catheter in comparison with an already existing catheter on the market. The study is a randomised, single blinded, cross-over study including 25 healthy males.
- Trial name
- Test catheter (NCT00832078)
- Testing
- SpeediCath Compact Male, Speedicath
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Healthy Volunteer
A Study of DISC-3405 in Healthy Volunteers
This phase 1 study will assess the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of DISC-3405 in adult male and female healthy volunteers.
- Trial name
- NCT06050915
- Testing
- DISC-3405
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Disc Medicine, Inc
Constipation
A Trial in Healthy Volunteers, to Evaluate the Tolerability and Cardiac Safety of Prucalopride
An escalating dose of prucalopride up to a maximum of 20 mg was given once daily to 32 healthy volunteers to determine safety at the maximum tolerable dose or at 20 mg.
- Trial name
- NCT00488215
- Testing
- prucalopride
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Movetis
Healthy Volunteers
Safety and Pharmacokinetics Study of Multiple Ascending Doses of VV261 Tablets
This is a randomized, double-blind, placebo-controlled, multiple ascending-dose study to evaluate the safety, tolerability and pharmacokinetics characteristics of VV261 tablets in healthy adults.
- Trial name
- NCT07710326
- Testing
- VV261 600mg TID group, VV261 900mg TID group
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vigonvita Life Sciences
Healthy Volunteers
Pharmacokinetics of Irbesartan High/Amlodipine FDC and Co-administration of Irbesartan High and Amlodipine in Healthy Volunteers
The purpose of this study is to compare pharmacokinetics and safety of Irbesartan High and Amlodipine Fixed Dose Combination and coadministration of mono compounds in healthy adult volunteers
- Trial name
- NCT05688085
- Testing
- Irbesartan High/Amlodipine FDC, Irbesartan High, Amlodipine
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Handok Inc.
Healthy Volunteer
A Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of RO6864018 in Male, Healthy, Asian Participants
This randomized, double-blind, placebo-controlled, single ascending dose study will assess the safety, pharmacokinetics, and pharmacodynamics of RO6864018 in healthy, male, Asian and Caucasian participants.
- Trial name
- NCT02015715
- Testing
- RO6864018
- Where
- 2 sites in Singapore
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy Volunteers
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MA-0211 in Healthy Adult Subjects Including a Food Effect Cohort
This first-in-human (FiH) study consists of 2 parts: single ascending dose (SAD) with evaluation of food effect (Part 1) and multiple ascending dose (MAD) (Part 2).
- Trial name
- NCT03682484
- Testing
- MA-0211
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Healthy Volunteers
A Positron-emission Tomography Study to Determine Brain Exposure of [11C]Savolitinib in Healthy Volunteers
The purpose of this study is to measure brain exposure of [11C]savolitinib in healthy volunteers. This study will determine brain exposure of [11C]savolitinib in up to 8 healthy volunteers under physiological conditions, ie, when…
- Trial name
- NCT06348355
- Testing
- [11C]savolitinib, Savolitinib
- Where
- Sweden
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.