Clinical trials: Healthy Volunteers.
Healthy Subjects
A Study of SYHA1805 in Healthy Subjects
This is a Phase Ib study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple-dose of SYHA1805.
- Trial name
- NCT04977570
- Testing
- SYHA1805 tablets
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Healthy Volunteers - Haemophilia A
A Research Study of How a New Medicine NNC0365-3769 (Mim8) Works in the Body of Healthy People
NN0365-3769 (Mim8) is a study medicine with the potential to prevent and reduce bleeding in people with haemophilia A (an inherited disorder in which blood does not coagulate properly).
- Trial name
- NCT05127473
- Testing
- Mim8 B, 10 mg/mL, Mim8 B, 100 mg/mL
- Where
- 2 sites in Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy
A Study to Investigate Efficacy and Safety of NSI-8226 in Healthy Participants
A Phase 1 Randomized, Double-Blind Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Bioavailability of NSI-8226 in Healthy Participants.
- Trial name
- NCT06640920
- Testing
- Cohort A, Cohort B, Cohort C
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Uniquity One (UNI)
Healthy
A Study to Investigate the Different Modes of (S) Ketamine Administration in Healthy Participants
The purpose of this study is to determine the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of different modes of (S) ketamine administration in healthy participants.
- Trial name
- NCT03808259
- Testing
- (S)-ketamine Oral Thin Film, (S)-ketamine IV Infusion
- Where
- Belgium
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy Volunteers
Study of Celecoxib Bioavailability in Healthy Subjects
To evaluate the bioavailability of celecoxib administered as capsule contents sprinkled onto applesauce relative to intact capsule
- Trial name
- NCT00296127
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
DDI Study to Investigate Interaction Between Amikacin and POL7080
Single-center, open-label, 2-sequence, 3-period crossover drug-drug interaction study. Repeated doses of POL7080 and repeated doses of amikacin will be administered alone or combined.
- Trial name
- NCT02897869
- Testing
- POL7080, Amikacin, POL7080 + Amikacin
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Polyphor Ltd.
Healthy Participant
Drug-Drug Interaction Study of Itraconazole With GST-HG171/Ritonavir in Healthy Participants
The purpose of this study is to estimate the effect of a strong inhibitor of CYP3A4 (itraconazole) on the pharmacokinetics (PK) of GST-HG171/ritonavir in healthy participants.
- Trial name
- NCT06087055
- Testing
- GST-HG171/Ritonavir, Itraconazole
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fujian Akeylink Biotechnology Co., Ltd.
Healthy Volunteer
A Study to Compare the Effect of Omadacycline Versus Moxifloxacin in Healthy Adult Volunteers
This is a randomized (1:1), double-blind, double-dummy, phase I study to compare the effects of Omadacycline versus Moxifloxacin on gut microbiota and the resistomes in healthy adult volunteers.The study consists of 3 phases…
- Trial name
- NCT06462326
- Testing
- Moxifloxacin Oral Tablet, Omadacycline Oral Tablet
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zai Lab (Hong Kong), Ltd.
Infections, Bacterial
To Assess Bioavailability, Food Effect and Pharmacokinetics of Gepotidacin Tablets: A Phase I, Single-Dose, 2 Part Study in Healthy Subjects.
This study is divided in 2 parts. Part 1a is being conducted to evaluate the safety, tolerability, and relative bioavailability of the 2 free base tablet formulations (roller compacted [RC] and high shear wet granulation [HSWG])…
- Trial name
- NCT02853435
- Testing
- Gepotidacin RC Tablet, Gepotidacin HSWG Tablet, Gepotidacin Capsule
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Safety, Tolerability, PK, PD, ADA of Escalating Single Dose of CJ-40002 in Healthy Male Subjects
The objectives of this study are: To evaluate the safety and tolerability of CJ-40002 after single SC injection in healthy male volunteers. To evaluate the PK of CJ-40002 after single SC injection in healthy male volunteers.
- Trial name
- hGH (NCT02146625)
- Testing
- CJ-40002
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Idiopathic Pulmonary Fibrosis, Lung; Disease, Interstitial, With Fibrosis
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of RSN0402 in Healthy Volunteers
This is a phase 1, randomized, First in Human (FIH), double-blinded, placebo-controlled study to assess the safety, tolerability, and PK of RSN0402 in healthy volunteers.
- Trial name
- NCT06482190
- Testing
- RSN0402 Part 1, RSN0402 Part 2
- Where
- 3 sites in Australia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shenzhen Resproly Biopharmaceutical Co., Ltd
Healthy
Glucophage Extended Release (GXR) China Bioequivalence Study (Nantong - Darmstadt)
The study will assess the bioequivalence between single doses of GXR manufactured in Merck Nantong China (test drug) and GXR manufactured in Merck Darmstadt Germany (reference drug) under fed and fasted state in healthy…
- Trial name
- NCT03566810
- Testing
- Test GXR, Reference GXR
- Where
- China
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Healthy
Study to Determine the Ability of Seresis to Act as a Skin Protection Agent in Healthy Young Female Volunteers
Study to detect the efficacy of Seresis® in reducing the damage produced on the skin by Matrix-metalloproteinases (MMP) and by oxidative stress (marker: heme oxygenase-1 expression) activated by UV radiation
- Trial name
- NCT02191813
- Testing
- Seresis®
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Midazolam in Healthy Male Volunteers
The objective of the study was to investigate the effect of BIRT 2584 XX and its metabolite BI 610100 when BIRT 2584 XX is administered as a tablet to near steady state in estimated high therapeutic dose on the pharmacokinetics…
- Trial name
- NCT02256748
- Testing
- BIRT 2584 XX, Midazolam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study to Investigate the Effects of Gastric Acid Suppression by Rabeprazole and BMS-986165 on How Fast and Complete The Drug is Absorbed Into the Body of Healthy Participants
The purpose of this study is to evaluate the effects of stomach acid suppression by rabeprazole and BMS-986165 on how fast and complete the drug is absorbed into the body of healthy participants.
- Trial name
- NCT03979248
- Testing
- BMS-986165, Rabeprazole
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy
Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults
The primary objective of this study was to compare the single-dose relative bioavailability of Alpharma Branded Products Division (Kadian®) and Ligand® Pharmaceuticals Inc.
- Trial name
- NCT00782548
- Testing
- KADIAN (morphine sulfate sustained-release) capsules, Avinza (morphine sulfate sustained-release) capsules
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Pain, Neuropathic
Gabapentin and Donepezil Combination on Experimental Human Pain Models
This study will compare the effects of gabapentin alone, and gabapentin + donepezil given together in two types of experimental electrical pain tests in up to 48 healthy male subjects (after 24 recruited in the first cohort an…
- Trial name
- NCT01485185
- Testing
- Gabapentin lower dose, Donepezil, Gabapentin higher dose
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
A Study Comparing Four Different Rivoceranib Tablets in Healthy Participants
The main purpose of this trial is to compare a single dose of 4 different rivoceranib tablets in healthy adult participants.
- Trial name
- NCT05287360
- Testing
- Rivoceranib
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elevar Therapeutics
Healthy, Renal Insufficiency
Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Kidney Function and Healthy Participants
The main purpose of this study is to measure how much of pirtobrutinib (LOXO-305) gets into the bloodstream and how long it takes the body to eliminate it in participants with impaired kidney function and healthy participants.
- Trial name
- NCT06190678
- Testing
- Pirtobrutinib
- Where
- 5 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy
BIIB014 Cardiovascular Monitoring Study
The study will examine the effects of a single dose of BIIB014 on blood pressure and haemodynamic variables in healthy volunteers over 24 hours.
- Trial name
- NCT01035515
- Testing
- BIIB014 50mg, BIIB014 100mg
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Biogen
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