Clinical trials: Healthy Young
Hepatitis A
A Study to Evaluate the Safety and Immunogenicity of the Hepatitis A Virus Vaccine HAVpur in Healthy Young Children
This is a study to test whether vaccination with HAVpur Junior against hepatitis A provides protection that is non-inferior to the protection afforded by vaccination with Havrix 720 Junior.
- Trial name
- NCT01349829
- Testing
- HAVpur Junior, Havrix 720 Junior
- Where
- 3 sites in India
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV
Healthy
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42165279 in Healthy Young and Elderly Participants
The purpose of this study is to assess the safety, tolerability, and pharmacokinetics of JNJ-42165279 in healthy, young and elderly, male and female participants after repeated oral dose administration.
- Trial name
- NCT01964651
- Testing
- JNJ-42165279 50 mg, JNJ-42165279 100 mg, JNJ-42165279 30 mg
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Pharmacokinetics
Pharmacokinetic Properties of Vortioxetine in Healthy Young Chinese Men and Women
The purpose of this study is to determine the pharmacokinetic (PK) parameters of vortioxetine after single and multiple oral dosing to healthy Chinese men and women.
- Trial name
- NCT02386488
- Testing
- Vortioxetine 10 mg single dose, Vortioxetine 20 mg single dose, Vortioxetine 10 mg multiple dose
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Shigella, Diarrhea
First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in Healthy Young Adults
Phase 1 trial to evaluate the Safety and Immunogenicity of Inventprise's (IVT) Shigella-04 in Healthy Young Adults
- Trial name
- NCT07205926
- Testing
- IVT Shigella-04
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inventprise Inc.
Alzheimer's Disease
Study to Evaluate Safety, Pharmacokinetics and Pharmacodynamics of CHF5074 in Healthy Young Male Subjects
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple oral doses of CHF5074 in young healthy male volunteers.
- Trial name
- CT02 (NCT01203384)
- Testing
- CHF5074 1x, CHF5074 2x, CHF5074 3x
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CERESPIR
Adult Young and Healthy
Effects of Daily Almond Intake as a Preload Before Meals Versus as a Snack Among Korean Adults
The study was conducted to investigate the effects of daily almond intake based on the timing of almond consumption (i.e., almond consumption as a preload or between-meal snack) on body composition, lipid profile, and oxidative…
- Trial name
- NCT03014531
- Testing
- almond, high-carbohydrate control food
- Where
- South Korea
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- ICAN Nutrition Education and Research
Healthy
An Interaction Study of Ketoconazole/Verapamil Versus AZD1305
The purpose is to study whether ketoconazole or verapamil have an effect on how AZD1305 is handled by the body, i.e the absorption, distribution, metabolism and excretion, when administered in combination with AZD1305.
- Trial name
- NCT00707551
- Testing
- Ketoconazole, Verapamil, AZD1305
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Clinical Trial, Phase I
Study in Healthy Young Women to Investigate the Pharmacodynamics, Pharmacokinetics and Safety of Vilaprisan
This is a study in healthy women of reproductive age to investigate the pharmacodynamics (mainly ovarian activity), pharmacokinetics and safety of vilaprisan after daily oral administration of 4 different doses over 84 days…
- Trial name
- NCT02262663
- Testing
- Vilaprisan (BAY1002670)
- Where
- 2 sites in Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bayer
Atrial Fibrillation
An Interaction Study With Digoxin and AZD1305
The primary purpose of this study is to learn more about how digoxin is handled by the body, i.e. absorption, distribution, metabolism and excretion, when administered alone and in combination with AZD1305.
- Trial name
- NCT00712465
- Testing
- AZD1305, Digoxin
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
A Bioavailability Study Comparing Modified-release Capsules and Immediate Release Capsules in Fed and Fasting Conditions
Part 1: The purpose of this study is to determine the pharmacokinetic profile of 4 different Extended/modified-release formulations and one immediate release formulation of AZD1446.
- Trial name
- NCT01092299
- Testing
- AZD1446
- Where
- 2 sites in Sweden
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Influenza
Immunogenicity and Safety Study of a Booster Vaccination With a Recombinant H5N1 Influenza HA Vaccine in Primed Adults
The study is designed to assess the immunogenicity and safety of one booster vaccination with 45 μg of a recombinant H5N1 influenza (A/Indonesia/05/2005) HA vaccine in healthy young adults, previously primed with a…
- Trial name
- NCT01195038
- Testing
- Recombinant Influenza HA Vaccine (H5N1)
- Where
- 2 sites in Japan
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- UMN Pharma Inc.
Chronic Pain
AZD1386 Japanese Multiple Ascending Dosing Study
This is a single centre, double-blind, randomised, parallel group, placebo controlled study to assess the safety, tolerability and pharmacokinetics of AZD1386 when given as multiple doses to 32 (24 healthy young and 8 healthy…
- Trial name
- JMAD (NCT00736658)
- Testing
- AZD1386
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Depressive Disorder
GSK372475 PK Study in Healthy Volunteers
This study will consist of 4 parallel cohorts of healthy volunteers (elderly male, elderly female, young male and young female). Subjects will receive either GSK372475 1.5mg or placebo for 28 days.
- Trial name
- NCT00728208
- Testing
- GSK372475
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Children
An Exploratory RWE Study Exploring Effects of a Goat Milk Based Young Child Formula on Health Benefits
This is an exploratory real-world study designed to gain insight into the role of the product in terms of health benefits in toddlers, with the potential to generate hypotheses on key and other exploratory objectives.
- Trial name
- NCT06287385
- Testing
- Goat-milk Based Formula
- Where
- China
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Danone Nutricia
Contraception, Ovulation Inhibition
Inhibition of Ovulation and Pharmacokinetics of Transdermal Ethinylestradiol (EE) and Gestodene (GSD)
Investigation of two transdermal hormone patch formulations for contraception regarding inhibition of ovulation over a period of 3 treatment cycles in healthy young female volunteers
- Trial name
- NCT00915915
- Testing
- Ethinylestradiol/Gestodene (BAY86-5016)
- Where
- 2 sites in Germany
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Bayer
Phase 1 Safety Study of GelVac Nasal Powder H5N1 Influenza Vaccine
Study to Assess Safety of an Inactivated H5N1 Influenza Vaccine Administered in GelVac Nasal Powder to Healthy Young Adults
This is a double-blind, placebo controlled, safety and immunogenicity study of GelVac™ nasal powder H5N1 influenza vaccine. Healthy male and female subjects between 18 and 49 years of age who are eligible for study participation…
- Trial name
- NCT01258062
- Testing
- GelVac™ nasal powder H5N1 influenza vaccine.
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Alzheimer Disease, Healthy
Study GSI-136 in Healthy Young and Healthy Elderly Subjects
This is a first-in-humans study of GSI-136, a drug being developed for the treatment of Alzheimer Disease. The main purpose of this study is to determine whether GSI-136 is safe and tolerable in healthy young and healthy elderly…
- Trial name
- NCT00718731
- Testing
- GSI-136
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Healthy Subjects
A Study to Assess the Effects of Single Ascending Doses of ASP1707 in Healthy Young Japanese Male Subjects
Three groups of 8 Japanese males are given single ascending doses of ASP1707 or placebo to assess the safety and tolerability, and to evaluate how it is absorbed, metabolized and distributed through the body.
- Trial name
- NCT02146742
- Testing
- ASP1707
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Healthy
Study Of Single Ascending And Multiple Doses Of PF-04447943 In Japanese Subjects.
This study is designed to investigate the safety, tolerability, and pharmacokinetics of PF-04447943 after single and multiple-dose administration to healthy young adult and elderly Japanese subjects, respectively.
- Trial name
- NCT00959803
- Testing
- PF-04447943
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Randomized Phase I Study of a Hepatitis B Antigen Combined With IMP321
This is a single centre, three single administrations (Days 1, 29 and 57) at increasing doses of IMP321 (3, 10, 30 and 100 µg) in four cohorts of 12 subjects, single blind, randomized study.
- Trial name
- NCT00354861
- Testing
- hepatitis B antigen (without alum) plus IMP321, hepatitis B antigen alone (without alum), Engerix B
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Immutep S.A.S.