Clinical trials: Healthy Young Men
Healthy Young Men
Effect of Acute Grape Seed Extract Supplementation on the Heart Rate Recovery in Young Individuals
This study hypothesized that sustained sympathoexcitation via MMA slows down PHRR and that GSE supplementation is effective at improving PHRR in young individuals.
- Trial name
- NCT07137988
- Testing
- 600 mg grape seed extract, 600 mg Starch
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Healthy Volunteers, Pharmacodynamics of Mirabegron
A Study in Healthy Young Men to Look at What Drives the Cardiovascular Effects After Dosing With Mirabegron.
To explore what is driving heart-rate increases after dosing with mirabegron. Subjects will be given a beta-blocker at the same time as mirabegron.
- Trial name
- NCT01284868
- Testing
- mirabegron, Bisoprolol, propranolol
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy Men
Metabolic Availability of Lysine From Sorghum in Adult Men
Protein is the key determinant of growth and bodily functions. The quality of food proteins depend on their amino acid content and the amount of amino acids used by the body to make proteins.
- Trial name
- NCT03411005
- Testing
- Metabolic availability of lysine in sorghum
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Insulin Resistance
ACTIV- Exercise Intervention in Healthy Young Men
The study is designed to compare muscle energy capacity in men with obesity or diabetes as compared to athletes. This study will also enable researchers to determine whether MRS can replace muscle biopsy for this type of…
- Trial name
- NCT00401791
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Fertility Disorders
Effects of Lifestyle Changes on Semen Quality in Healthy Young Men Living in Highly Polluted Areas (FAST)
We planned a randomized controlled trial (RCT) with the main aim to evaluate the effects of lifestyle changes on semen quality in healthy young men living in polluted areas in Italy.
- Trial name
- FAST (NCT04012385)
- Testing
- lifestyle counseling
- Where
- 4 sites in Italy
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale Salerno
Muscle Hypertrophy, Muscle Strength
Upper Versus Lower Limb Responses to Higher Versus Lower Load Resistance Training in Young Men
Recent research suggests that performing resistance exercise training with relatively light loads is equally as effective at increasing muscle mass and muscle strength as performing resistance exercise training with relatively…
- Trial name
- NCT03993483
- Testing
- Unilateral resistance exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Disuse Atrophy
Bed-rest, Muscle Mass and Insulin Sensitivity
In the present study, the effects of 7 days of bed rest on muscle mass, muscle fiber characteristics and insulin sensitivity will be determined.
- Trial name
- NCT02109380
- Testing
- Bed rest
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus, Type 2, Cardiovascular Disease
Moderate Alcohol Consumption, Fat and Carbohydrate Metabolism and Insulin Sensitivity
Moderate alcohol consumption is associated with a decreased risk of diabetes type 2. This association could be mediated by an improvement of insulin sensitivity with moderate alcohol consumption.
- Trial name
- NCT00364767
- Testing
- A, B
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- TNO
Healthy
Influence of Daylong Glycemia on Detraining Induced Metabolic Changes
Aim of the study is to investigate the impact of glycemic index (provided as soft drinks) on changes in insulin sensitivity, metabolic flexibility, and arterial stiffness in response to detraining.
- Trial name
- NCT02321033
- Testing
- soft drinks
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Healthy, Osteopenia
Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-BMD (NCT07187518)
- Testing
- Measurements with the POROUS R4C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine
- Where
- 2 sites in Germany
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Bioavailability of Amino Acids Following Oral Ingestion of Plant-Based Proteins in Young, Healthy Men
Bioavailability of Plant Protein Amino Acids
This study aims to inform of the mechanism of action of plant-based protein by measuring the bioavailability (i.e. rate of appearance and magnitude of concentration in the circulation following oral ingestion) of key amino acid…
- Trial name
- NCT04872530
- Testing
- Pea-protein concentrate, Fava-bean protein concentrate, Chickpea protein concentrate
- Where
- Ireland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Healthy
Effect of GLP-1 on Glucose Metabolism in CNS Assessed by PET
10 healthy men will be PET-scanned (CNS) twice in random order with infusions of placebo or Native GLP-1 during hyperglycemic clamp to uncover the metabolic effects of GLP-1 in perspectives of intervention of macrovascular late…
- Trial name
- NCT01185119
- Testing
- native glp-1 (7-36)
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy Adults
Metabolic Availability of Lysine From White Maize
Our objective is to determine the metabolic availability of Lysine in white maize using the indicator amino acid oxidation (IAAO) technique in adult men.
- Trial name
- NCT02018575
- Testing
- Crystalline Lysine Amino Acid Mix, White corn meal porridge
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy Young Men
Aronia Berry Consumption on Vascular Function
There is an increasing interest in the effects of various food derived polyphenols on vascular function. Arguably the most well-established vascular benefits are attributed to flavanols from cocoa beans and this has been…
- Trial name
- NCT03041961
- Testing
- Aronia full spectrum, Aronia extract
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- King's College London
Diabetes, Exercise Physiology
Elevated FFA and Skeletal Muscle Lipid Content
There is increasing evidence that skeletal muscle lipid content (IntraMyoCellular Lipid, IMCL) markedly increases the risk of metabolic complications, including insulin resistance and cardiovascular events.
- Trial name
- NCT01906333
- Testing
- Exercise, Glucose, Fasted
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy
Regulation of Metabolism and Ion Handling
This study investigates the relation between ion-handling (K+) and fatigue development during exercise. Before and after a 6-week period of high intensity interval training, performance and ion-handling is assessed in young…
- Trial name
- NCT03317704
- Testing
- Speed endurance training
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Muscle Hypertrophy in Healthy Young Men
Chronic Beta2-adrenergic Stimulation and Cardiac and Skeletal Muscle Hypertrophy
Studies in animals have shown that beta2-adrenoceptor activation with selective agonists regulates protein metabolism and muscle growth in skeletal and cardiac muscle tissue.
- Trial name
- NCT02551276
- Testing
- Salbutamol, Resistance training
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Muscle Hypertrophy in Healthy Young Men
Effects of Deloading Periods in Resistance Training on Muscular Strength and Hypertrophy
This study investigates the effects of deloading periods (short breaks or reductions in training volume) in a 8-week resistance training program on muscle strength and hypertrophy in young, untrained individuals.
- Trial name
- DPRT (NCT06825052)
- Testing
- Resistance Training with Deloading Periods, Continuous Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Healthy
T Cell Responses to Various Levels of Exercise Stress
The objective of this project is to quantify the immunoendocrine response to acute stress events combining both physical and psychological challenges.
- Trial name
- NCT06638684
- Testing
- Exercise
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Healthy
Glutamate Supplementation in Young Men
Amino acids play an important role in human metabolism. In aging individuals and in some diseases, certain amino acids, such as glutamate, are at lower than normal levels.
- Trial name
- NCT03425578
- Testing
- MSG, CHO
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Waterloo