Clinical trials: Hearing
Meniere's Disease
SPI-1005 for the Treatment of Patients With Meniere's Disease
This study will evaluate the safety, efficacy, and Pharmacokinetics (PK) of two dose levels of SPI-1005 administered for 28 days compared to placebo in patients with Meniere's disease.
- Trial name
- NCT03325790
- Testing
- 200mg SPI-1005 BID, 400mg SPI-1005 BID
- Where
- 13 sites in United States
- Volunteers
- 149 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Tinnitus
Clinical Trial of Sound-Based Versus Behavioral Therapy for Tinnitus
The purpose of this study is to determine if a novel sound-based therapy in comparison to standard of care (cognitive behavioral therapy) results in reducing tinnitus-related effects for people with bothersome tinnitus.
- Trial name
- NCT03022084
- Testing
- Desyncra, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- VA National Center for Rehabilitative Auditory Research
Sudden Sensorineural Hearing Loss
Oral Statins and Protection From Hearing Loss
A small clinical trial for idiopathic sudden sensorineural hearing loss (ISSNHL). Will the addition of an oral statin to the standard treatment (oral methylprednesolone and the salvage therapy of intratympanic dexamethasone)…
- Trial name
- NCT04826237
- Testing
- Statin, methylprednisolone, dexamethasone
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Northwestern University
Presbycusis, Aging
Evaluating Hearing Aid Service Delivery Models
The purpose of this study is to compare the outcomes for two different hearing-aid delivery models. In one model, the audiologist selects and fits the hearing aid and, in the other model, the consumer does this directly.
- Conditions
- Presbycusis, Aging, Hearing Loss
- Trial name
- NCT01788423
- Testing
- hearing aid
- Where
- United States
- Volunteers
- 323 people
- Sponsor
- Indiana University
Tinnitus
Auditory-somatosensory Stimulation to Alleviate Tinnitus
The purpose of this study is to develop and test a subject operated device to lessen tinnitus (ringing in the ear), based on subject-feedback for stimulus presentation.
- Trial name
- NCT02974543
- Testing
- Active Treatment: Bimodal auditory-somatosensory stimulation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan
Tinnitus
High Dose Oxytocin Nasal Spray for Treatment of Tinnitus
The purpose of this study is to evaluate the effects of high-dose intranasal oxytocin for treating tinnitus. The hypothesis is that high dose intranasal oxytocin can significantly reduce tinnitus severity and disability.
- Trial name
- NCT04210310
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Hearing Impairment
The Performance-Perceptual Test as a Counseling Tool
The purpose of the study is to determine whether a new test of ability to understand speech in noise and an associated counseling program can improve hearing aid satisfaction.
- Trial name
- PPT (NCT00126113)
- Testing
- PPT-based Counseling, Standard Educational Counseling
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- US Department of Veterans Affairs
Sensorineural Hearing Loss, Noise Induced Hearing Loss
FX-322 in Adults With Stable Sensorineural Hearing Loss
This is a phase 2a single and repeat dose exploratory efficacy study of intratympanic FX-322 compared to placebo in healthy male and female adults with stable sensorineural hearing loss.
- Conditions
- Sensorineural Hearing Loss, Noise Induced Hearing Loss, Sudden Sensorineural Hearing Loss
- Trial name
- NCT04120116
- Testing
- FX-322 (One Dose), FX-322 (Two Doses), FX-322 (Four Doses)
- Where
- 16 sites in United States
- Volunteers
- 95 people
- Sponsor
- Frequency Therapeutics
Hearing Disability
Product Testing of the FaceView Mask™: Usability Survey
The study aims to gather participants' perceptions of the novel transparent surgical N95 respirator vs. a conventional surgical N95 respirator.
- Trial name
- NCT04854694
- Testing
- FaceView Mask™, conventional surgical N95 respirator
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Hearing Loss
Antioxidation Medication for Noise-induced Hearing Loss
This study will examine whether oral intake of 1200mg N-Acetylcysteine/day will prevent temporary threshold shift in hearing among workers exposed to noise
- Trial name
- NCT00552786
- Testing
- N-acetylcysteine (NAC), glucose
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hearing Loss
Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial
This longitudinal study evaluates the possible benefit of cochlear implantation in the poor ear of adults with asymmetric hearing loss who continue to use a hearing aid in the better hearing ear.
- Trial name
- NCT03052920
- Testing
- Cochlear implant
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Tinnitus, Pulsatile Tinnitus
Venous Sinus Stenting To Treat Intractable Pulsatile Tinnitus Caused By Venous Sinus Stenosis
There have been few published studies that examine the efficacy and safety of endovascular treatments on patients with pulsatile tinnitus with venous stenosis.
- Conditions
- Tinnitus, Pulsatile Tinnitus, Venous Sinus Stenosis, Dural Sinus Stenosis
- Trial name
- NCT02734576
- Testing
- Venous Sinus Stenting with the Precise Pro Stent
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Weill Medical College of Cornell University