Clinical trials: Hearing Implants
Severe to Profound Sensorineural Hearing Loss
Correlations Between Subjective and Objective Responses to Cochlear Implant Stimulation
Cochlear implants have been used for several decades, with major technological advances. However, adjustment can be difficult for patients who have to get used to a new sound that is electrical rather than acoustic.
- Trial name
- CRSOSIC (NCT07371299)
- Testing
- Objective electrophysiological measures (eCAP, eABR, eSRT)
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hearing Loss, Cochlear Implant
Cochlear Trauma, Functional and Structural Preservation in Cochlear Implant Surgery
Prospective 2-arm cohort consisting of a preoperative visit and visits at the time of implantation (Day 0) and follow-up in patients for whom their treating physician indicated a perimodiolar or straight cochlear implant.
- Conditions
- Hearing Loss, Cochlear Implant, Cochlear Microphonics, Electrocochleography
- Trial name
- NCT05079867
- Testing
- Cochlear implantation
- Where
- Argentina
- Volunteers
- 40 people
- Sponsor
- Hospital Italiano de Buenos Aires
Sensorineural Hearing Loss, Bilateral Hearing Loss
Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array
A long-term follow-up of Cochlear's cochlear implant electrode array which passively elutes dexamethasone for a defined period of time to help reduce inflammatory responses.
- Trial name
- CI-DEX-LTFU (NCT06936449)
- Testing
- CI632D, CI632
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Cochlear
Influence of Anatomy Based Frequency Mapping on Speech Outcomes and Hearing Related Measures
Anatomy-based Fitting in Unexperienced Cochlear Implant Users
The present study investigates CI users' potential differences in speech tests, other performance measures (i.e. pitch-matching, perception of timbre and melodic intervals, consonance perception), and patient-reported outcome…
- Trial name
- NCT05684393
- Testing
- frequency distribution type
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Dominik Riss
Hearing Impairment, Sensorineural
A Feasibility Study Evaluating the Performance of Focused Multipolar Stimulation and Sound Coding in Adults.
The purpose of this early feasibility study is to explore several facets of hearing performance of Focused Multipolar stimulation in adult cochlear implant users.
- Trial name
- SASC (NCT05641155)
- Testing
- Focused Multipolar Stimulation (FMS) strategy
- Where
- 5 sites in United States, Belgium
- Volunteers
- 18 people
- Sponsor
- Cochlear
Cochlear Hearing Loss
MeasurIng and Restoring Auditory Awareness for Cochlear Implant Listeners in noisE
The goal of this interventional study is to describe how people with cochlear implants perceive the perceive speech in noise and their sound environment on adults who are native French speakers with typical hearing or with…
- Trial name
- MIRACLE (NCT06420921)
- Testing
- Speech in noise comprehension test, Objective tests of perception of ambient sound cues in noise, Subjective tests of perception of ambient sound cues in noise
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Hearing Loss, Unilateral, Hearing Loss, Profound
Iowa Cochlear Implant Clinical Research Center Study of SSD Using Med-El Cochlear Implants
The purpose of this study is to understand the speech perception in noise and in quiet and localization benefits in a laboratory setting in listeners that receive a cochlear implant in an ear with severe to profound hearing loss…
- Trial name
- NCT03929809
- Testing
- Cochlear Implant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Iowa
Speech Disorders
Effect of Hearing Aid Versus Cochlear Implant on Hearing and Speech Recognition in Children
This study examines the comparative effects of hearing aids and cochlear implants on hearing and speech recognition in children with hearing loss.
- Trial name
- NCT06913517
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Superior University
Deafness; Perception
Programming Cochlear Implant With Artificial Intelligence
This thesis project proposes to investigate the "state of the art" of the programming of the cochlear implant. In the center of audiophonologie Brussels, the classic 'manual programming' has been in use over 20 years and also the…
- Trial name
- CI_AI (NCT03700268)
- Testing
- Manual intervention to programme Cochlear Implant electrodes
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Hearing Loss
Clinical Study of Cochlear Implants in Adults With Asymmetrical Hearing Loss
The objective of this study is to investigate benefits of binaural hearing for non-traditional cochlear implant candidates (with Asymmetric Hearing Loss).
- Trial name
- NCT02004535
- Testing
- Cochlear Implantation
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Washington University School of Medicine
Hearing Loss, Complete
Evaluation of a Bio-inspired Coding Strategy for Cochlear Implant Users
This study will determine the facilitation, refractoriness and spatial spread effects of auditory nerve fiber responses to electrical stimulation via a cochlear implant.
- Trial name
- EBCS (NCT03726684)
- Testing
- Coding strategy for cochlear implants
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hearing Loss, Sensorineural, Cochlear Implantation
Evaluation of the Automated Integration of a Robotics and ECochG System for Use With Cochlear Implant Surgery
Evaluation of the Automated Integration of a Robotics and ECochG System for Use with Cochlear Implant Surgery
- Trial name
- AIMBOT (NCT06664710)
- Testing
- iotaSOFT Insertion System with AIM, iotaSOFT Insertion System with AIM Control
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- iotaMotion, Inc.
Deafness Unilateral, Deafness, Bilateral
Cochlear Implant Electrostimulation and the Influence on the Vestibular Organ
There is evidence that the sensor function of the utricle in patients with bilateral labyrinthine dysfunction (bilateral vestibulopathy) may improve balance under the influence of high frequency basal stimulation of the cochlea.
- Conditions
- Deafness Unilateral, Deafness, Bilateral, Deafness Congenital, Deafness, Acquired
- Trial name
- NCT05073796
- Testing
- Cochlea Implant
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- RWTH Aachen University
Hearing Loss, Bilateral Sensorineural
A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults
This pivotal study examines the clinical efficacy and safety of an investigational totally implantable cochlear implant (TICI) system.
- Trial name
- ELEVATE (NCT07287124)
- Testing
- Cochlear implant
- Where
- 11 sites in United States
- Volunteers
- 56 people
- Sponsor
- Cochlear
Cochlear Hearing Loss, Hearing Loss
Remote Evaluation of the Naída CI M90 (Marvel) Sound Processor
Within-subject comparison. Remotely Evaluating latest Advanced Bionics Marvel Sound Processor for cochlear implants, from two adult groups.
- Trial name
- NCT05007886
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Sensorineural Hearing Loss, Hearing Loss
Quantification of Visually Evoked Cortical Potentials in Individuals With Hearing Loss
This research is being done to determine whether a test that measures a "Visual Evoked Potential" can be used in a new way for individuals that have hearing loss.
- Trial name
- NCT05107466
- Testing
- P300 Visually evoked potential
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hearing Loss
Scalar Localization Cochlear Electrode Array Using 64 Slice CT
Insertion of electrode array in scala vestibuli, rather than the preferred location within scala tympani, leads to loss of native hearing in those patients with isolated high-frequency hearing loss undergoing cochlear…
- Trial name
- NCT00587262
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Cochlear Prosthesis Implantation
Electrocochleography Along Cochlear Implant Auditory Rehabilitation
Electrocochleography (eCochG) is an electrophysiological measurement to evaluate the activity of cochlear hair cells in response to acoustic stimulation.
- Trial name
- eCochGIC (NCT04561388)
- Testing
- Electrocochleography, Pure Tone Audiometry, Speech audiometry
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Hearing Loss
Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial
This longitudinal study evaluates the possible benefit of cochlear implantation in the poor ear of adults with asymmetric hearing loss who continue to use a hearing aid in the better hearing ear.
- Trial name
- NCT03052920
- Testing
- Cochlear implant
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Acoustic Neuroma, Labyrinthitis Ossificans
Maintaining Cochlear Patency After VIIIth Nerve Surgery
Tumors arising from the VIIIth Nerve (vestibulo-cochlear nerve) typically present with progressive unilateral hearing loss and tinnitus.
- Conditions
- Acoustic Neuroma, Labyrinthitis Ossificans, Profound Hearing Impairment
- Trial name
- NCT03261726
- Testing
- MedEl Test Electrode Placer
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System