Clinical trials: Heart; Complications
Venous Thromboembolism
Remote Home Prothrombin Time (PT)/International Normalized Ratio (INR) Monitoring and Patient Management System
Long-term anticoagulation is indicated in patients for the prophylaxis and/or treatment of the thromboembolic complications associated with atrial fibrillation and/or mechanical cardiac valve replacement, prevention or treatment…
- Trial name
- vMetrics-AMS (NCT00978445)
- Testing
- vMetrics protocol
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- ZIN Technologies, Inc.
Hypertension, Diabetes Mellitus, Type 2
Enhancing Community Health Through Patient Navigation, Advocacy and Social Support
Some patients who have multiple long-term health conditions have significant challenges accessing needed services despite available primary care and social services resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- ENCOMPASS (NCT03077386)
- Testing
- ENCOMPASS Intervention
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- University of Calgary
Pain, Postoperative
Parasternal Subpectoral Plane Blocks for Cardiac Surgery Via a Midline Sternotomy
To better determine whether parasternal subpectoral plane blocks (PSPB) infusing bupivacaine for midline sternotomy decreases opioid consumption and pain scores.
- Trial name
- NCT04788056
- Testing
- Parasternal Subpectoral Plane Block
- Sponsor
- Brigham and Women's Hospital
Hemodynamic Instability, Cardiovascular Complication
Evaluation of Cardiac Functions in Deep Trendelenburg Position
Robotic-assisted laparoscopic prostatectomy (RALP) is a surgical method with good short-term results and accepted as the gold standard because of its minimal invasiveness.
- Trial name
- NCT05685979
- Testing
- Robotic-assisted laparoscopic prostatectomy in deep Trendelenburg position.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Acibadem University
Perioperative/Postoperative Complications, Outcome
Evaluation of BIomarkers for POstoperative Complications in Non-cardiac Surgery Patients
Aim of this study is to evaluate whether the periopertive course is able to predict postoperative complications. Several approaches will be choosed to optimize perioperative risk stratification predicting postoperative…
- Trial name
- NCT03765372
- Where
- Germany
- Volunteers
- 1,598 people
- Sponsor
- Technical University of Munich
Postoperative Complications
Personalized Hemodynamic Therapy in Patients Undergoing High-risk Surgery
The purpose of this study is to evaluate the effectiveness of using the personal preoperatively assessed cardiac output in high-risk patients to guide perioperative administration of fluids and vasoactive drugs on predefined…
- Trial name
- TAPIR (NCT02834377)
- Testing
- Treatment algorithm targeting individual cardiac output
- Where
- Germany
- Volunteers
- 188 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Ischemia, Bypass Complications
Study of Remote Ischemic Postconditioning
Cardiac surgery is associated with cardiac and cerebral injury because of ischemia/reperfusion in approximately one third of cases.
- Trial name
- NCT01450475
- Testing
- Remote ischemic postconditioning
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Xijing Hospital
Fetal Cardiac Anomaly, Gestational Diabetes
Fetal Cardiac Remodeling in Gestational Diabetic Pregnancies at the Moment of Diagnosis
The aim of the present study will be to evaluate whether fetal cardiac remodeling is already present at the moment of the diagnosis of gestational diabetes (GD) in comparison with fetuses of healthy pregnant women.
- Trial name
- NCT05260931
- Testing
- Fetal echocardiography
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Healthy
Effects of Teduglutide on Cardiac Repolarisation and Conduction in Healthy Male and Female Volunteers
The primary objective of this trial is to investigate if teduglutide has an effect on cardiac repolarisation (QT, QTc interval).
- Trial name
- NCT01028924
- Testing
- Teduglutide
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Nycomed
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Central Venous Catheterization
Comparison of the Oblique-axis and Long-axis Approaches for Axillary Vein Catheterization Under Ultrasound Guidance
Ultrasound-guided axillary vein catheterization can be performed via the oblique-axis and long-axis approaches of the axillary vein.
- Trial name
- NCT04962945
- Testing
- Oblique-axis approach group, Long-axis approach group
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Guowei Tu
Ischemic Heart Disease
Exploration of Cerebral Pathophysiology During and After CABG Using CPB
Purpose: The purpose of this study is to examine cerebral oxidative and inflammatory stress and cerebral hemodynamics during and after coronary artery bypass grafting and correlate with postoperative cognitive function.
- Trial name
- NCT02941380
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiac Surgery Patient, Postoperative Pain
Effect of Intraoperative Morphine on Postoperative Pain After CABG
Ethics committee approval was obtained for this study, which was planned as a prospective, randomized, controlled, single-center trial to be conducted in patients undergoing coronary artery bypass grafting (CABG) surgery between…
- Conditions
- Cardiac Surgery Patient, Postoperative Pain, Pain After Surgery
- Trial name
- NCT07472959
- Testing
- In this study, morphine administration, which is routinely and frequently used in our operating room for patients undergoing CABG, was applied as an additional intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Disease, Coronary Artery Bypass Grafting
Comparative Outcomes of Mammary Artery Harvesting: Infection, Occlusion Rates and Thoracic Pain Assessment
The COMFORT Trial is a randomized controlled superiority trial comparing skeletonized (SK) versus non-skeletonized (non-SK) harvesting of the left internal mammary artery (LIMA) to left anterior descending artery (LAD) graft in…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Surgical Site Infection
- Trial name
- COMFORT (NCT07720661)
- Testing
- Skeletonized LIMA Harvesting, Non-Skeletonized LIMA Harvesting
- Sponsor
- Hamilton Health Sciences Corporation
Pulmonary Complications
Effectiveness Of Modified Chest PT Technidue In Pre And Post-Operative Program In Patients Open Heart Surgery
The purpose of this study is to explore effectiveness of modified chest physical therapy techniques using new device in pre and post-operative program in patients undergoing open heart surgery
- Trial name
- NCT02894879
- Testing
- BreatheMAX®, Routine treatment
- Where
- Thailand
- Volunteers
- 48 people
- Sponsor
- Khon Kaen University
Heart Failure
Calcium, Phosphate, Renal Impairment and Coronary Artery Disease in the Cardio-renal Syndrome, The CAPRICORN-CRS Study
Heart failure (HF) is a major public health problem, which affects about 5 million Americans.HF is when the heart muscle does not pump as much blood as the body needs.
- Trial name
- CAPRICORN (NCT00853541)
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Vasoplegia
Postoperative Hemodynamics Comparison After High Spinal Block With or Without Intrathecal Morphine.
There is paucity of literature on the effects of intrathecal morphine on the postoperative hemodynamics in the cardiac-surgical patients.We planned this study to compare the post-operative hemodynamic effects (particularly the…
- Trial name
- NCT02825056
- Testing
- Bupivacaine, Bupivacaine + Morphine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Atrial Fibrillation, Surgery--Complications
Novel Methods for Characterizing Patients With Post-operative Atrial Fibrillation Secondary to Abdominal Surgery
Purpose The primary purpose of the current project is to characterize unselected patients undergoing surgery developing post-operative atrial fibrillation (POAF), ultimately leading to a new risk-stratification model.
- Trial name
- NCT04090918
- Testing
- Cardiac examination programme 3 months after abdominal surgery
- Where
- Denmark
- Sponsor
- Frederiksberg University Hospital
Hypertension
Valsartan in Cardiovascular Disease With Renal Dysfunction (The V-CARD) Study
The purpose of this study is to investigate if an angiotensin II receptor blocker, valsartan 160 mg/day is more effective to reduce the incidence of cardiovascular events as compared to 40 mg/day in patients with moderate renal…
- Trial name
- NCT00140790
- Testing
- valsartan
- Where
- 2 sites in Japan
- Volunteers
- 1,000 people
- Sponsor
- Kumamoto University
Infection, Heart Failure
Hospital-Level Care at Home for Acutely Ill Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Infection, Heart Failure, COPD, Asthma
- Trial name
- NCT03203759
- Testing
- Home hospitalization, Traditional inpatient hospitalization
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Brigham and Women's Hospital
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