Clinical trials: Heart; Complications
Neurocognitive Disorders, Surgery-Complications
Cerebrolysin in Prevention of Postoperative Delirium in Cardiac Surgery
Postoperative delirium (POD) and postoperative neuropsychological dysfunction are frequently noted in critically ill patients undergoing elective or emergency surgery and treated in the intensive care unit (ICU).
- Conditions
- Neurocognitive Disorders, Surgery-Complications, Critical Illness, Brain Damage
- Trial name
- Cereb-POD (NCT05864677)
- Testing
- Cerebrolysin
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lublin
Genetic Polymorphism
The Role of Platelet Surface α2β1 Integrin Expression as a Risk Factor in Thrombotic and/or Bleeding Complications
This study will begin to define these critical determinants for patients undergoing procedures in the hybrid interventional cardiology/cardiac surgery suite.
- Trial name
- NCT00603148
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- Vanderbilt University
End Stage Renal Disease, Cardiac Insufficiency
Invasive Monitoring of Pulmonary Artery Pressure (PAP) Among Dialysis Treated Patients
The purpose of this study is examine whether invasive pulmonary artery pressure (PAP) monitoring could be beneficial for the patients in dialysis treatment.
- Trial name
- NCT02862197
- Where
- Finland
- Volunteers
- 8 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Acute Renal Failure, Acute Kidney Injury
Early Diagnosis of Postoperative Acute Renal Failure-using Biomarker to Predict Outcome of Cardiac Surgery Associated Acute Kidney Injury
The purpose of this study is to determine soluble HJV could be an early diagnosis urinary biomarker of ischemia/reperfusion injury in post CPB-patients.
- Trial name
- NSARF (NCT01503710)
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Extracorporeal Membrane Oxygenation Complication
Use of Nafamostat Mesilate for Anticoagulation in Patients With ECMO
The purpose of this study is to evaluate the effectiveness and safety of nafamostat mesilate compared with unfractionated heparin for anticoagulation in patients with ECMO after cardiac surgery.
- Trial name
- NCT06276010
- Testing
- nafamostat mesilate, unfractionated heparin group
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiaotong Hou
Sternotomy, Postoperative Pain
Erector Spinae Plane Block in Post-operative Recovery in Cardiac Surgery With Median Sternotomy.
This study aim is to measure the time of extubation in patients receiving ultrasound guided bilateral Erector Spinae Plane (ESP) block after cardiac surgery .
- Trial name
- NCT05356715
- Testing
- Ultrasound guided bilateral ESBP
- Where
- 2 sites in Egypt
- Volunteers
- 239 people
- Sponsor
- Kasr El Aini Hospital
Cardiac Disease
Opioid Reduced Anesthesia With Parasternal CATheters on Postoperative Delirium After Cardiac Surgery
PostOperative Delirium (POD) is the most common neuropsychiatric complication following cardiac surgery and may be related to morphine consumption.
- Trial name
- ORACAT (NCT05880615)
- Testing
- collection of datas
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Chest Pain
Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome
The main objective of our study is to evaluate the diagnostic value of copeptin testing in association with troponin HS testing during pre-hospital care (ambulance care) in the treatment of patients whose pattern of use is the…
- Trial name
- SCA COP (NCT02116426)
- Testing
- Blood work in the ambulance, Blood work upon arrival in the emergency room, Blood work at 3 hours post-arrival in the emergency room
- Where
- 2 sites in France
- Volunteers
- 320 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Out-of-Hospital Cardiac Arrest
AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA
The investigators aimed to evaluate the effect of AMCPR (Augmented-Medication CardioPulmonary Resuscitation: administration of additional vasopressin to titrate to arterial diastolic blood pressure over 20 mmHg) on…
- Trial name
- NCT03191240
- Testing
- Vasopressins, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- Asan Medical Center
Pain, Postoperative, Surgery
Postop Pain in the MICS Patients Versus Sternotomy Patients
To adequately assess postoperative pain in the coronary artery bypass surgical population a multicentered retrospective chart review was carried out; the study utilized a nonexperimental comparative descriptive study design.
- Trial name
- NCT04003584
- Testing
- Coronary bypass surgery
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Turner's Syndrome
Growth Hormone Treatment for the Prevention of Short Stature in Young Girls With Turner Syndrome Before the Age of 4 Years
The objective of this study is to evaluate the efficacy and safety of recombinant human growth hormone (r-hGH) treatment in girls with Turner Syndrome under the age of 4 years.
- Trial name
- NCT01066052
- Testing
- r-hGH
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Nephrotic Syndrome
Cardiac Performance Evaluation in Children With Steroid Dependent vs Steroid Resistant Nephrotic Syndrome
nephrotic syndrome (NS) is one of the most common pediatric kidney diseases There is an increased incidence of heart disease in patients with primary nephrotic syndrome (PNS) compared to the normal population Conventional…
- Trial name
- NCT06622915
- Testing
- Tissue Doppler imaging and Conventional Echocardiography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Heart Failure, Chronic Kidney Diseases
Kaiser Permanente Evaluation of Medically Tailored Meals in Adults With Medical Conditions at High Readmission Risk
This study is a virtual, remote, decentralized pragmatic clinical trial comparing the efficacy of medically tailored meals alone or medically tailored meals with remote nutritional counseling compared with usual standard of care…
- Conditions
- Heart Failure, Chronic Kidney Diseases, Diabetes Mellitus, Type 2
- Trial name
- KP NOURISH (NCT05166525)
- Testing
- Medically tailored meals
- Where
- 5 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Kaiser Permanente
Cardiorenal Syndrome
Exercise Rehabilitation for Cardiorenal Syndrome in HFrEF Patients
This study aims to investigate the efficacy and safety of exercise rehabilitation in patients with cardiorenal syndrome (CRS). Building on previous research demonstrating that exercise rehabilitation can effectively improve…
- Trial name
- NCT07167368
- Testing
- Standardized Basic Drug Therapy for HFrEF with Chronic Kidney Dysfunction, Home-based Personalized Exercise Rehabilitation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Haiyan Pan
Preeclampsia
Hemodynamic Measurements in Women With Serious Preeclampsia
This trial is examining hemodynamic measurements in women with serious preeclampsia.
- Trial name
- NCT00199810
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- Oslo University Hospital
Breast Cancer, Cardiac Toxicity
Side Effects Involving the Heart in Women With Breast Cancer Receiving Doxorubicin and Trastuzumab
RATIONALE: Studying samples of blood and tissue in the laboratory from women receiving doxorubicin and trastuzumab for breast cancer may help doctors learn more about changes that occur in DNA and identify biomarkers for…
- Conditions
- Breast Cancer, Cardiac Toxicity, Cardiovascular Complications
- Trial name
- PACE in BC (NCT00875238)
- Testing
- trastuzumab, doxorubicin hydrochloride, polymorphism analysis
- Where
- 4 sites in United States
- Volunteers
- 133 people
- Sponsor
- Vanderbilt University
Cardiorenal Syndrome, Acute Kidney Injury
Effect on Kidney Function Recovery Guiding Decongestion With VExUS in Patients With Cardiorenal Syndrome 1
During cardiorenal syndrome type 1 (CRS1) vascular congestion is the major contributor to worsening renal function, but promoting decongestion with routine clinical evaluation is ineffective in some patients.
- Conditions
- Cardiorenal Syndrome, Acute Kidney Injury, Decompensated Heart Failure, Fluid Overload
- Trial name
- NCT05927285
- Testing
- Vexus, Control group
- Where
- Mexico
- Volunteers
- 140 people
- Sponsor
- Hospital Civil de Guadalajara
Postoperative Delirium
Plasma Proteomics in Patients With Postoperative Delirium
Patients undergoing cardiac surgery were recruited. Baseline characteristics of all subjects were collected. The 3-minute Delirium diagnostic Scale (3D-CAM) was used to screen the POD group and non-POD group from the recruited…
- Trial name
- NCT05772026
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Acute Kidney Injury
Deferoxamine for the Prevention of Cardiac Surgery-Associated Acute Kidney Injury
Multiple lines of evidence support a central role of iron in causing acute kidney injury (AKI), including the finding that prophylactic administration of iron chelators attenuates AKI in animal models.
- Trial name
- DEFEAT-AKI (NCT04633889)
- Testing
- Deferoxamine, Normal saline
- Where
- 3 sites in United States
- Volunteers
- 320 people
- Sponsor
- Brigham and Women's Hospital
Heart Transplantation, Chronic Renal Insufficiency
Genetic Predictors of Renal Dysfunction Following Heart Transplantation
Kidney disease is a common problem after heart transplantation. It may be caused by anti-rejection medications such as cyclosporine or tacrolimus.
- Trial name
- NCT01686191
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.