Clinical trials: Heart; Complications
Complications Due to Coronary Artery Bypass Graft, Coronary Artery Disease
Neurological Complications Comparing Endoscopically vs. Open Harvest of the Radial Artery
Coronary artery bypass grafting (CABG) using the radial artery (RA) has since the nineties gone through a revival. The initially reported worse outcome in RA graft patients compared to patients grafted with the saphenous vein…
- Conditions
- Complications Due to Coronary Artery Bypass Graft, Coronary Artery Disease, Myocardial Ischemia, Coronary Disease
- Trial name
- NEO (NCT01848886)
- Testing
- Endoscopic radial artery harvest, Open radial artery harvest, Mammarioradial graft (Y-graft)
- Where
- Denmark
- Volunteers
- 301 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Uric Acid
Uric Acid and Surgical Prognosis
Preoperative serum uric acid significantly impacted mortality and morbidity in non-cardiac surgery.
- Trial name
- NCT06837545
- Testing
- No Intervention (Observational Study)
- Where
- South Korea
- Volunteers
- 309,353 people
- Sponsor
- Asan Medical Center
Ischemic Heart Disease, Post-Operative Complications
On-Pump vs. Off-Pump CABG in High-Risk Patients (EuroSCORE 6+)
Previous studies comparing on-pump and off-pump operating strategy did only partially demonstrate benefits of the off-pump myocardial revascularisation.In primary end-points (MI, death, renal failure, and so on) there was no…
- Trial name
- PRAGUE 6+ (NCT00606372)
- Testing
- OPCAB - the off-pump coronary artery bypass
- Where
- 2 sites in Czechia
- Volunteers
- 220 people
- Sponsor
- Charles University, Czech Republic
Fascicular Block, Motor Activity
The Effects of Different Clonidine Concentrations on Axillary Brachial Plexus Block With 1,5% Lidocaine
The purpose of this study is to determine whether different clonidine concentration on axillary brachial plexus block with 1,5% lidocaine for upper limb surgery may influence the sensory and motor block onset time and duration…
- Conditions
- Fascicular Block, Motor Activity, Pain, Postoperative, Latency Period
- Trial name
- NCT01620112
- Testing
- high Clonidine concentration, low clonidine concentration, Lidocaine
- Volunteers
- 60 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Acute Postoperative Pain
Intertransverse Process Block to Improve Quality of Recovery After Cardiac Surgery With Sternotomy
The goal of this clinical trial is to evaluate the efficacy of intertransverse process block (ITPB) in blunting sympathetic response of sternotomy, achieving perioperative opioid-sparing and improving quality of recovery in adult…
- Trial name
- NCT06926764
- Testing
- Intertransverse process block, Levobupivacaine 0.25%, Sodium Chloride (NaCl) 0.9 %
- Sponsor
- Chinese University of Hong Kong
Acute Renal Injury, Preventive Measures
Prevention and Early Detection and Intervention of Post-Coronary Artery Bypass Grafting Surgery (CABG) Acute Kidney Injury (AKI)
Nephrology participation in care of patients undergoing CABG could reduce AKI through correction of modifiable risk factors and early detection and intervention of post-op AKI.
- Trial name
- NCT02838667
- Testing
- Standard of Care plus Nephrology Care
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Mayo Clinic
Cardio Respiratory Arrest, Cardiac Death
Ventilation in Cardiac Arrest
Over the last decades, research in cardiopulmonary resuscitation was primarily focused on uninterrupted chest compressions to restore sufficient circulation.
- Conditions
- Cardio Respiratory Arrest, Cardiac Death, Ventilation Therapy; Complications, Apnea
- Trial name
- VICA (NCT04657393)
- Testing
- mechanical ventilation
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Cardiac Pacing, Permanent Pacemaker Implantation
Ultrasound-Guided PECS II Block for Permanent Pacemaker Implantation
This single-center, prospective, randomized, controlled clinical trial aims to evaluate whether ultrasound-guided PECS II block, when added to standard local infiltration anesthesia, improves perioperative analgesia in patients…
- Conditions
- Cardiac Pacing, Permanent Pacemaker Implantation, Postoperative Pain
- Trial name
- PACE-PECS (NCT07739407)
- Testing
- Ultrasound-Guided PECS II Block, Standard Local Infiltration Anesthesia
- Volunteers
- 72 people
- Sponsor
- ferdi gülaştı
Acute Coronary Syndrome
Reduce Bolus Injection of Bivalirudin
There are fewer studies on the bleeding risk of the currently administered bivalirudin bolus injection dose and the safety of bivalirudin in patients with CKD.
- Trial name
- NCT03588611
- Testing
- Bivalirudin
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Han Yaling, MD
Thyroid Diseases, Heart Diseases
Interest of the SPECT-CT Scan SUVspect in the New Generation of Gamma-cameras With Semiconductor
Since 2017, a revolution began in the departments of nuclear medicine, with the routine use of gamma-cameras with semiconductor.
- Conditions
- Thyroid Diseases, Heart Diseases, Bone Diseases, Brain Diseases
- Trial name
- GAMMA-CAM (NCT03414021)
- Testing
- SPECT-CT Scan
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Lille Catholic University
Heart Arrest, Cardiac Arrest
Resuscitation Outcomes in the Netherlands
The Resuscitation Outcomes in the Netherlands - study assesses one-year survival and quality of life after In-Hospital Cardiac Arrest(IHCA).
- Conditions
- Heart Arrest, Cardiac Arrest, Cardiac Arrest as A Complication of Care, Outcome, Fatal
- Trial name
- ROUTiNE (NCT03120507)
- Where
- 12 sites in Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Cardiac Catheterization
Effect of Animated Education on Anxiety and Vascular Complications
An animated education program about cardiac catheterization will be presented 24 hours to children in the intervention group before undergoing cardiac catheterization.
- Trial name
- VAEdA (NCT06483087)
- Testing
- Animated Education Program
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- University of Jordan
Hypotension, Very Low Birth Weight Infants
N-Terminal Pro-B-Type Natriuretic Peptide and Troponin Levels as Markers of Hemodynamic Stability in Very Low Birth Weight Infants During the First Days of Life
The primary objective is to test the hypothesis that there is an association between the hemodynamic status and the serum levels of NT-proBNP and cTnT in prematurely born infants.
- Conditions
- Hypotension, Very Low Birth Weight Infants, Ventricular Dysfunction, Prematurity
- Trial name
- NCT00425581
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Delirium, Postoperative, Delirium in Old Age
The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium
Sleep disturbances, cognitive reserve, and continuing pain and inflammation are other risk factors contributing to delirium (confusion and agitation) and neurocognitive decline (in the long term) following heart surgery.
- Trial name
- SCOPE (NCT06721819)
- Testing
- Sleep Hygiene, Brain Game, and IV Acetaminophen Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 406 people
- Sponsor
- Beth Israel Deaconess Medical Center
Heart Failure, Renal Failure
The Effects of Carperitide on Short and Long-term Prognosis in Patients With Both Cardiac and Renal Failure
Carperitide (alpha-human atrial natriuretic peptide) improves systemic hemodynamics in patients with heart failure through a vasodilatory action, a natriuretic action, and inhibition of the renin-angiotensin-aldosterone system…
- Trial name
- NCT00613964
- Testing
- Carperitide heart failure therapy, Standard heart failure therapy
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Nara Medical University
Thromboembolism, Cardiac Event
Influence of Cardiac Implantable Electronic Devices on the Hemostatic System
The hemostasis system is one of the many biological systems of the human body, designed to preserve the liquid state of blood and prevent its loss during vascular injuries.
- Conditions
- Thromboembolism, Cardiac Event, Hemostatic Disorder
- Trial name
- NCT04499612
- Testing
- Cardiac implantable electronic device implantation., Cardiac implantable electronic device replace., Duplex ultrasound.
- Where
- Russia
- Volunteers
- 250 people
- Sponsor
- Ryazan State Medical University
Postoperative Complications, Cardiovascular Complication
Perioperative Inflammatory Response Assessment in High-risk Patients Undergoing Noncardiac Surgery
Postoperative cardiovascular complications are common after noncardiac surgery. The association between perioperative inflammation and the occurrence of cardiovascular complications after surgery is still unknown.
- Conditions
- Postoperative Complications, Cardiovascular Complication, Myocardial Ischemia, Inflammation
- Trial name
- INSIGHT (NCT04753307)
- Testing
- Laboratory measurements
- Where
- Austria
- Volunteers
- 1,400 people
- Sponsor
- Medical University of Vienna
Testicular Cancer, Survivorship
Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors
Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant
- Conditions
- Testicular Cancer, Survivorship, ASCVD, Coronary Artery Disease
- Trial name
- NCT05611307
- Testing
- Lipid profile, Coronary artery assessment, Hormone levels for hypogonadism
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Postoperative Pain
Parasternal Block and TENS for Cardiac Surgery
the objective of the present study was to compare the efficacy of TENS and parasternal block with local anesthetic infiltration in relieving pain during the first 24 h period following median sternotomy.
- Trial name
- NCT02725229
- Testing
- parasternal block, TENS group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Antalya Training and Research Hospital
Bedwetting, Nocturnal Enuresis
Randomized Study Of Novel Enuresis Alarm vs Standard Bedwetting Alarm
Identify the dry night rate in patients using the GoGoband® nocturnal enuresis device vs a standard Pflaundler bedwetting alarm.
- Conditions
- Bedwetting, Nocturnal Enuresis, Urinary Incontinence
- Trial name
- NCT05214131
- Testing
- gogoband, SNEA group
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Yale University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.