Clinical trials: Heart Arrest, Out-Of-Hospital
Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation
PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)
The PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE) study is a pilot feasibility trial evaluating the implementation of pre-hospital targeted temperature management (TTM) using a wearable surface…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation, Death, Sudden, Cardiac, Therapeutic Hypothermia
- Trial name
- PRECEDENCE (NCT07421882)
- Testing
- CarbonCool® Cooling Vest
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Cardiac Arrest
Basic Life Support Termination of Resuscitation Implementation Study
In Ontario, most people who experience a cardiac arrest at home (when their heart stops beating) only receive basic life support from Primary Care Paramedics (PCPs) and all are transported to the hospital.
- Trial name
- NCT00370461
- Where
- 7 sites in Canada
- Volunteers
- 350 people
- Sponsor
- Sunnybrook Health Sciences Centre
Out-of-hospital Cardiac Arrest (OHCA)
Out-of-hospital Cardiac Arrest Epidemiology and Outcomes in Western Lithuania 2022-2028
Out-of-hospital cardiac arrest rate is common problem, because of high mortality rate. It is not clear incidence rate, epidemiology and outcomes in Lithuania
- Trial name
- NCT07622082
- Testing
- Protocol based
- Volunteers
- 4,000 people
- Sponsor
- Lithuanian University of Health Sciences
Out-Of-Hospital Cardiac Arrest
Differential Diagnosis and Cause-specific Treatment During OHCA
Differential diagnosis: ultrasound, blood gas analyse combined with examination of the patient and environment is used during Out Of Hospital Cardiac Arrest (OHCA) to screen possible underlying cause of cardiac arrest.
- Trial name
- NCT04670354
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Out-of-hospital Cardiac Arrest
Immediate Unselected Coronary Angiography Versus Delayed Triage in Survivors of Out-of-hospital Cardiac Arrest Without ST-segment Elevation
The aim of the trial is to compare immediate angiography in survivors of out of hospital cardiac arrest (OHCA) without ST-segment elevation versus delayed/selective catheterization with respect to 30 day mortality.
- Trial name
- TOMAHAWK (NCT02750462)
- Testing
- Immediate coronary angiography, Delayed/selective coronary angiography
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- University Hospital Schleswig-Holstein
Sudden Cardiac Arrest
Sodium Bicarbonate in Cardiopulmonary Resuscitation
Out-of-hospital cardiac arrests (OHCA) account for over 60% of deaths from coronary artery disease. The annual incidence of OHCA treated by Emergency Medical Systems (EMS) is 41-89 per 100,000 population.
- Trial name
- SB CAT (NCT01377337)
- Testing
- sodium bicarbonate
- Where
- 2 sites in Israel
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Cardiac Arrest, Out-Of-Hospital, Hypotension
Cardiac Arrest - Ultrasound Detection of Occult Perfusion
The goal of this study is to describe the population of patients presenting after out of hospital cardiac arrest with occult perfusion, defined as a patient without a palpable pulse but with some evidence of pulsatile arterial…
- Trial name
- NCT07897370
- Where
- 8 sites in United States
- Volunteers
- 1,400 people
- Sponsor
- University of Massachusetts, Worcester
Out-of-hospital Cardiac Arrest
Evaluation of Out-of-Hospital Cardiac Arrest Recognition by Non-physicians Dispatchers in a French Emergency Dispatch Call Center
The purpose of this study is to measure an improvement in the detection rate of cardiac arrest (CA) in the Dispatch Center as a result of debriefings and repeated trainings for non-medical operators who receive emergency calls.
- Trial name
- OCAR (NCT01992419)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Fire Brigade Of Paris Emergency Medicine Dept
Cardiac Arrest With Successful Resuscitation
Gasping Improves Long-term Survival After Out-of-hospital Cardiac Arrest
The aim of our retrospective clinical study was to examine the association between agonal breathing, return of spontaneous circulation (ROSC), and long-term survival.
- Trial name
- NCT02998749
- Volunteers
- 584 people
- Sponsor
- Charles University, Czech Republic
Cardiac Arrest, Metabolic Acidosis
Bicarbonate in Patients With Out-of-hospital Cardiac Arrest
A pilot study to evaluate the effect of sodium bicarbonate administration on cardiopulmonary resuscitation results and outcomes in cardiac arrest patient with severe metabolic acidosis.
- Trial name
- NCT02303548
- Testing
- Sodium bicarbonate, Normal saline
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Out-of-Hospital Cardiac Arrest, Blood Pressure
Blood Pressure and OXygenation Targets After OHCA
This study compares two blood pressure targets and two oxygenation targets in the post-resuscitation care of comatose out-of-hospital cardiac arrets patients.
- Conditions
- Out-of-Hospital Cardiac Arrest, Blood Pressure, Hemodynamic Instability
- Trial name
- BOX (NCT03141099)
- Testing
- Low normal MAP, High normal MAP, Low normal PaO2.
- Where
- 2 sites in Denmark
- Volunteers
- 802 people
- Sponsor
- Jesper Kjaergaard
Sudden Death, Out-Of-Hospital Cardiac Arrest
Head-to-pelvis Computed Tomography Evaluation of Sudden Death Survivors
Out-of-hospital arrest can occur from multiple etiologies. In patients without an obvious reason for the sudden-death event, diagnostic evaluation is not clear.
- Trial name
- NCT03111043
- Testing
- Head to pelvis CT scan
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- University of Washington
Out of Hospital Cardiac Arrest
Functional Outcome After Cardiac Arrest
Descriptive and prognosis study of the functional outcome after cardiac arrest for the patients awake within the first 15 days.
- Trial name
- HANOX (NCT02292147)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Arrest, Coma
GLP-1 Analogs for Neuroprotection After Cardiac Arrest
Experimental studies and previous clinical trials suggest neuroprotective effects of GLP-1 analogs in various degenerative neurological diseases, and in hypoxic brain injuries in experimental designs.
- Trial name
- GLIP1 (NCT02442791)
- Testing
- Byetta (Lilly, Exenatide), 20% Human Albumin
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Jesper Kjaergaard
Out-of-Hospital Cardiac Arrest
AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA
The investigators aimed to evaluate the effect of AMCPR (Augmented-Medication CardioPulmonary Resuscitation: administration of additional vasopressin to titrate to arterial diastolic blood pressure over 20 mmHg) on…
- Trial name
- NCT03191240
- Testing
- Vasopressins, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- Asan Medical Center
Out-Of-Hospital Cardiac Arrest
Post-resuscitation Care Registry for Survival From Out-of-hospital Cardiac Arrest
The aim of this study is to construct multi-center post-cardiac arrest care registry that can be used for data warehousing and clinical research.
- Trial name
- NCT03695718
- Where
- 3 sites in South Korea
- Volunteers
- 1,057 people
- Sponsor
- Seoul National University Hospital
Out-Of-Hospital Cardiac Arrest
P25/30 SSEPs and Neurological Prognosis After Cardiac Arrest
Study Title: Early recorded P25/30 somatosensory evoked potentials are associated with neurologic prognosis of comatose survivors after out of hospital cardiac arrest.
- Trial name
- NCT03881865
- Where
- United Kingdom
- Volunteers
- 93 people
- Sponsor
- University Hospital Plymouth NHS Trust
Out-of-Hospital Cardiac Arrest
Predicting Long-term Outcomes After Cardiac Arrest by Using Serum NGAL
This study was performed to determine the prognosis of patients after cardiac arrest using serum markers called NGAL. The initial NGAL values of patients with post-cardiac arrest syndrome are checked by blood tests, and the…
- Trial name
- NCT03615300
- Testing
- serum NGAL
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Uijeongbu St. Mary Hospital
Pediatric ALL, Cardiac Arrest
Effect of IAM With an I-gel® on Ventilation Parameters in Simulated Pediatric OHCA
Pediatric cardiac arrest occurs most in the prehospital setting. Most of them are due to respiratory failure (e.g., trauma, drowning, respiratory distress), where hypoxia leads to cardiac arrest.
- Conditions
- Pediatric ALL, Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation
- Trial name
- NCT05498402
- Testing
- i-gel ® device, bag-valve-mask ventilation
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Bystander, Chest Compression
REsuscitation Survey of Police Officers in New Taipei City for Duty
Out-of-hospital cardiac arrest (OHCA) remains a time-critical emergency where early cardiopulmonary resuscitation (CPR) and timely defibrillation using an automated external defibrillator (AED) are key to improving survival and…
- Conditions
- Bystander, Chest Compression, Out of Hospital Cardiac Arrest, AED
- Trial name
- RESPOND (NCT06955351)
- Testing
- Survey by Questionnaire
- Where
- Taiwan
- Volunteers
- 4,867 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital