Clinical trials: Heart Chambers
Atrial Fibrillation, Left Atrial Appendage Thrombosis
Intracardiac Echocardiography Guided Watchman Device Implant
This study is to look at the success of Intracardiac Echocardiography (ICE) in the Watchman procedure. Currently the process is to use a Transesophageal Echocardiography (TEE) to place the Watchman in patients.
- Trial name
- NCT06007872
- Testing
- Intracardiac Echocardiography (ICE)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Heart Failure, Bradycardia
Bolt CSP-M Holter Study
The purpose of this study is to investigate the cardiac electrical characteristics in different pacing outputs and body positions in LBB area pacing (LBBAP), from which the findings may help to develop and support data validation…
- Trial name
- NCT06540521
- Testing
- No intervention
- Where
- 2 sites in China
- Volunteers
- 95 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Amyloidosis Cardiac, Healthy Adults
Intracardiac Flow Assessment in Cardiac Amyloidosis
The primary objective of this study is to define the intracardiac flow imaging biomarkers in cardiac amyloidosis.
- Trial name
- NCT05379101
- Testing
- Cardiac magnetic resonance image (CMR), Transthoracic Echocardiogram (TTE), Six-minute Walk Test
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Atrial Fibrillation Paroxysmal
Zero-fluoroscopic Cryoballoon Ablation
This study aimed to investigate safety and efficacy of intracardiac echocardiography (ICE)-guided zero-fluoroscopic cryoballoon ablation (CBA) in patients with paroxysmal atrial fibrillation.
- Trial name
- NCT05711589
- Testing
- CBA was performed under intracardiac echocardiography guidance without fluoroscopy, cryoablation (CBA) was performed under fluoroscopic guidance
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pusan National University Hospital
Ventricular Tachycardia (VT), Ventricular Fibrillation
Evolution of Intracardiac Electrograms Recorded by Left Bundle Branch Pacing Lead in Patients With ICD or CRT-D
The goal of this observational study is to investigate the changes of LBB EGM during daily activities and overdrive pacing at the time of peri-implantation and up to 6-month follow-ups of ICD/CRT-D patients.
- Trial name
- NCT06745778
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Stroke, Intracardiac Thrombus
Brain MRI in Stroke Patients With Intracardiac Thrombus
Acute infarction patterns have been described in cardioembolic stroke, mainly with atrial fibrillation (AF) or patent foramen ovale.
- Trial name
- BRAIN IRM (NCT04456309)
- Testing
- No intervention,
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pacemaker, Defibrillators, Implantable
Correct Mobilization Time After Implantation of an Intracardiac Electronic Device Implantation
Bedrest is usually prescribed for patients management after cardiac electronic device implantation (CIED) in order to prevent complication.
- Trial name
- NCT06330675
- Testing
- Early mobilization, Standard of care
- Where
- Switzerland
- Volunteers
- 558 people
- Sponsor
- Caporali Elena
Atrial Fibrillation
FFS - Far Field Sensing Test Study in Cardiac Dual Chamber Pacemakers
The purpose of this study is to evaluate the effect of individual adjustment of the postventricular atrial blanking period in avoiding inappropriate mode switch of dual chamber pacemakers.
- Trial name
- NCT00196144
- Testing
- Individualized Programming of PVAB, Nominal PVAB
- Where
- Germany
- Volunteers
- 207 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Arrhythmia
Reduce Ventricular Pacing in Dual Chamber Implantable Cardioverter Defibrillators Using AutoIntrinsic Conduction Search Study
The purpose of this study is to determine if patients implanted with a St. Jude Medical (SJM) implantable cardioverter defibrillator (ICD) will benefit by using AutoIntrinsic Conduction Search (AICS) rather than only a programmed…
- Trial name
- NCT00187239
- Testing
- Autointrinsic Conduction Search Algorithm
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation
Simplified Pulmonary Vein Isolation Using singLe Catheter and IntraCardiac Echocardiography
Ablation for paroxysmal atrial fibrillation (PAF) by means of pulmonary vein isolation (PVI) is the principal method for the treatment of PAF.
- Trial name
- Simple-ICE (NCT04923009)
- Testing
- ICE visualization and map construction
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Centre of Postgraduate Medical Education
Atrial Fibrillation (AF)
LA Function After PFA in Paroxysmal AF
A prospective study that investigates the changes in LA echocardiographic parameters after PFA for paroxysmal AF.
- Trial name
- NCT07439016
- Testing
- LA and LAA function measurements
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Diabetes type1, Healthy
Impact of Gravity on Cardiac Hemodynamics
The goal of this clinical trial is to define and compare pre-load dependance of the cardiac function according to the intracardiac hydrostatic gradient of pressure in healthy and diabetic populations.
- Trial name
- ACUITY (NCT06190756)
- Testing
- Cardiovascular and Baroreflex stimulation by Tilting, Cardiovascular and Baroreflex stimulation by Lower Body Negative Pressure
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Left Ventricular Thrombus
Apixaban Versus Warfarin for Left Ventricular Thrombus
Left ventricular thrombus is a blood clot that forms in the left ventricle and is associated with risk of systemic embolism and ischemic stroke.
- Trial name
- APEX (NCT07709780)
- Testing
- Apixaban, Warfarin
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- University of Arizona
Primary Implantation of an Intracardiac Electronic Device Indication
Comparative Study of the Effectiveness of Three Access Routes for Implanting an Electronic Intracardiac Device
The implantation of an intra-cardiac electronic device (ICD) (pacemaker or defibrillator) is a frequent procedure, and one whose incidence is on the rise in the field of cardiology.
- Trial name
- MultiPM-ACCESS (NCT07273929)
- Testing
- Intervention 1: Cephalic vein dissection, Intervention 2 : Percutaneous echo-guided axillary route, Intervention 3 : Intrapocket ultrasound-guided axillary route
- Where
- 7 sites in France
- Volunteers
- 900 people
- Sponsor
- Hospices Civils de Lyon
Cardiac Pacemaker, Artificial, Cardiac Rhythm Disorder
Aveir DR i2i Study
Prospective, non-randomized, multi-center, international study designed to evaluate the safety and effectiveness of the Aveir™ Dual-Chamber (DR) Leadless Pacemaker system.
- Conditions
- Cardiac Pacemaker, Artificial, Cardiac Rhythm Disorder, Bradycardia
- Trial name
- NCT05252702
- Testing
- Aveir DR Leadless Pacemaker System
- Where
- 78 sites in United States, Austria and 11 more
- Volunteers
- 464 people
- Sponsor
- Abbott Medical Devices
Leiomyomatosis
Surgery for Intravenous Leiomyomatosis
Intravenous leiomyomatosis (IVL) with intracardiac extension is a rare benign smooth muscle tumor. Reviewing literature, intracardiac extension of the IVL has been reported in at least 70 cases. Most are individual case reports.
- Trial name
- SIVL (NCT01707862)
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Li Yang
Intracardiac and Septal Defects, Valve and Anulus Repair
Prospective and Non-randomized Registry of CardioCel 3D
Post-market, prospective, multi-centre, open-label, registry designed to collect prospective safety and performance data on the use of CardioCel in patients with cardiovascular disorders and in accordance with local standard of…
- Conditions
- Intracardiac and Septal Defects, Valve and Anulus Repair, Great Vessel Reconstruction, Peripheral Vessel Reconstruction
- Trial name
- NCT04175327
- Testing
- CardioCel implantation
- Where
- 6 sites in Germany, Italy and 2 more
- Volunteers
- 200 people
- Sponsor
- LeMaitre Vascular
Cardiac Amyloidosis, Cardiac Disease
High Resolution Three-dimensional Maps of the Right Chambers in Patient Diagnosed With Cardiac Amyloidosis
Amyloid heart disease is an accumulation of fibrillar proteins in the extracellular sector of the heart. Identified on echocardiography as Ventricular hypertrophy.
- Trial name
- CARTO-AMYLO (NCT04956965)
- Testing
- Cardiac electro-mapping
- Where
- Martinique
- Volunteers
- 24 people
- Sponsor
- University Hospital Center of Martinique
Safety of MR (Magnetic Resonance) Conditional CRT-pacemakers and ICDs
ProMRI PROVEN Master Study
This investigation is designed to provide supporting evidence for the clinical safety of the Ilesto/Iforia ICD (implantable cardioverter-defibrillator)system and the Evia/Entovis HF-T (Heart Failure) triple chamber pacemaker…
- Trial name
- NCT01809665
- Testing
- ICD/CRT-P therapy, MRI
- Where
- 23 sites in Australia, Austria and 6 more
- Volunteers
- 174 people
- Sponsor
- Biotronik SE & Co. KG
Myocardial Remodeling
Aldosterone Blockade to Prevent Myocardial Remodeling In Patients With Controlled Essential Hypertension
The goal of this project is to investigate the effects that the addition of aldosterone blockade with eplerenone will have on the progression of diastolic dysfunction in patients with controlled essential hypertension.
- Trial name
- Aldosterone (NCT00980031)
- Testing
- Eplerenone, Lactose Tablet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Creighton University