Clinical trials: Heart Chambers
Acute Myocardial Infarction
Effects of Cardiac Rehabilitation on High Mobility Group Box-1 Levels After Acute Myocardial Infarction
This purpose of this study is to examine the relationship between HMGB-1 and postinfarction predictors of outcome such as cardiopulmonary and echocardiographic parameters before and after a 6-month exercise-based cardiac…
- Trial name
- NCT00755131
- Testing
- Exercise-based Cardiac Rehabilitation program
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Federico II University
Ventricular Tachycardia
Brain Perfusion and Hemodynamic Stability in Patients Undergoing Radiofrequency Ablation of Ventricular Tachycardia
Ventricular tachycardia (VT) is a life-threatening, fast heart rhythm that starts in the lower chambers of the heart (the ventricles). This fast heartbeat is caused by abnormal electrical pathways located in the heart tissue.
- Trial name
- NCT01695551
- Testing
- Data Collection Forms
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Dhanunjaya Lakkireddy, MD, FACC
Atrial Fibrillation, Atrial Flutter
Comparison of Intracardiac Echocardiography and Transesophageal Echocardiography
The presence of intracardiac thrombi and their propensity for systemic embolism is a major concern in patients with atrial fibrillation (AF) and atrial flutter (AFL) undergoing cardioversion and ablation procedures.
- Trial name
- ICE-TEE (NCT02213666)
- Testing
- Intracardiac Imaging
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Elad Anter
Atrial Fibrillation (AF)
The Added Value of Three-dimensional Electroanatomic Mapping For Accurate Delivery Of Pulsed Field Ablation In The Pulmonary Veins Compared To Pulsed Field Ablation With Fluoroscopy And/Or Intracardiac Echocardiography Alone In The Treatment Of Atrial Fibrillation: MAP-PFA Study
This is a randomized control trial that aims to evaluate the added value of electro-anatomical mapping to improve the quality of pulse field ablation lesions during Atrial fibrillation ablation.
- Trial name
- MAP-PFA (NCT07014423)
- Testing
- The Pulsed Field Ablation to Isolate the Pulmonary Vein with the utilization of FARAVIEW mapping software., The Pulsed Field Ablation to Isolate the Pulmonary Vein without the utilization of FARAVIEW mapping software.
- Where
- 2 sites in Netherlands
- Volunteers
- 32 people
- Sponsor
- University Medical Center Groningen
Chronically (i.e. Implanted for at Least Six Months) Dual-chamber Pacemaker, Stable Cardiac Status (i.e. no Hospitalizations or Cardiac Medication Changes Within 3 Months)
Short Atrioventricular Delay Pacing
We intend to examine the effects of temporary elevation of atrial wall stress by shortening of the atrioventricular delay in patients with dual-chamber pacemakers.
- Trial name
- SAVD (NCT01233661)
- Testing
- short AVD pacing ; prior (stable) programming
- Where
- United States
- Sponsor
- University of Pittsburgh
Sinus Node Disease., First Degree Atrioventricular Block.
Minimizing Ventricular Pacing
The aim of this study is to evaluate the effect of minimizing right ventricular pacing in dual-chamber pacemaker patients with sinus node disease (SND) and first degree atrioventricular block (AVIB)on exercise capacity, quality…
- Trial name
- NCT01611389
- Testing
- Prolonging atrioventricular (AV) delay., Standard atrioventricular (AV) delay.
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Military Institute od Medicine National Research Institute
Sinus Node Disease, Atrial Fibrillation
Reducing Atrial Pacing Rate to Reduce Atrial Fibrillation in Patients With Sick Sinus Syndrome.
Atrial fibrillation (AF) is prevalent in patients with sick sinus syndrome (SSS) and associated with an increased risk of stroke and death.
- Trial name
- DANPACEII (NCT02034526)
- Testing
- DDDR-60, DDD-40
- Where
- Denmark
- Volunteers
- 540 people
- Sponsor
- Aarhus University Hospital
Atrial Fibrillation, Insulin Resistance
Insulin Resistance as a Predictor of Pulsed Field Ablation Success in Atrial Fibrillation (HOMA-PULSE)
This study investigates whether insulin resistance, a metabolic condition where the body's cells respond poorly to insulin, can predict the success of atrial fibrillation (AF) ablation using pulsed field ablation (PFA)…
- Conditions
- Atrial Fibrillation, Insulin Resistance, Catheter Ablation, Artificial Intelligence
- Trial name
- HOMA-PULSE (NCT07551947)
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Patent Foramen Ovale (PFO), High Altitude Pulmonary Edema
The Cardiovascular Effects of Patent Foramen Ovale in Hypoxia
Before birth, the foramen ovale is a normal opening in the heart that allows blood to flow from the mother to the baby. After birth, this opening usually closes.
- Trial name
- NCT07742540
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Mitral Regurgitation
Left Chamber Function in Mitral Regurgitation and Predicting Outcome After Replacement and Targeting for Early Surgery
The study aims to analyze the role of left ventricular and left atrial functional parameters by speckle tracking echocardiography in predicting outcome after mitral valve replacement and targeting for early intervention compared…
- Trial name
- NCT03870516
- Testing
- Mitral valve replacement, Speckle tracking echocardiography
- Volunteers
- 100 people
- Sponsor
- Assiut University
Persistent Atrial Fibrillation
Sevoflurane Versus Propofol Anesthesia in Intracardiac Echocardiography-Guided Atrial Fibrillation Ablation
This prospective, randomized, single-center study will compare sevoflurane inhalational anesthesia with propofol intravenous anesthesia in patients undergoing intracardiac echocardiography-guided radiofrequency catheter ablation…
- Trial name
- NCT07877116
- Testing
- Sevoflurane, propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Hüseyin Ulaş Pinar
Atrial Fibrillation, Acute Coronary Syndrome
Triple vs. Dual Therapy
Background: The acute coronary syndrome (ACS) is a complication of coronary artery disease (CAD) and associated with increased mortality.
- Trial name
- NCT02080858
- Testing
- Ticagrelor + Apixaban + ASA, Ticagrelor + Apixaban
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Tachyarrhythmia
Study to Verify Proper Detection of Supraventricular Tachyarrhythmia With Single-Lead Dual-Chamber Implantable Cardioverter-Defibrillators (ADRIA)
A unique single-lead dual-chamber implantable cardioverter-defibrillator (ICD) system (produced by Biotronik, Germany) features a conventional electrode in the ventricle (anchored in the ventricular apex) and a floating electrode…
- Trial name
- NCT00324662
- Testing
- Implantable cardioverter-defibrillator
- Where
- 10 sites in Germany, Switzerland
- Volunteers
- 260 people
- Sponsor
- Biotronik SE & Co. KG
Heart Chambers
Normal Values of Cardiac Measurements by Echocardiography in Chinese Based on Artificial Intelligence
Establish echocardiographic normal reference values of Chinese Han adults based on artificial intelligence.
- Trial name
- NCT06234241
- Testing
- Echocardiography
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tianxin Dong
Atrial Fibrillation
Evaluation of 4D Intracardiac Echocardiography (ICE) During Structural Heart and Electrophysiology Procedures
The purpose of this study is to evaluate the imaging performance and procedural safety of a prototype 4D ICE catheter during real-time intracardiac imaging and to optimize device imaging parameters, compared with current standard…
- Trial name
- 4D-ICE (NCT07806890)
- Testing
- 4D ICE Adjunct Imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Hypertrophic Cardiomyopathy
Natural History and Results of Dual Chamber (DDD) Pacemaker Therapy of Children With Obstructive Hypertrophic Cardiomyop...
Several studies have shown that specialized pacemaking devices (DDD pacing) can improve the symptoms associated with hypertrophic cardiomyopathy (HCM) in adults.
- Trial name
- NCT00001396
- Testing
- Paragon Pacemaker
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Type 2 Diabetes Mellitus, Coronary Artery Disease
Platelet-dependent Thrombosis: a Placebo-controlled Trial of Antiplatelet Therapy (Clopidogrel)
Patients with diabetes are more likely to develop furring of their coronary arteries and present with angina and heart attacks. Furthermore, after such an event, they have poorer outcomes (higher rates of death) and survivors are…
- Trial name
- NCT00728156
- Testing
- clopidogrel
- Where
- 2 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust