Clinical trials: Heart Defects
Heart Disease Congenital
The Swiss Registry for Heart Diseases in Children Living in Switzerland. SPHC
The Swiss Pediatric Heart Cohort aims to collect representative longitudinal data on all children diagnosed with a clinically relevant heart disease in Switzerland.
- Trial name
- SPHC (NCT04442685)
- Where
- Switzerland
- Volunteers
- 590 people
- Sponsor
- University Children's Hospital, Zurich
Atrial Septal Defect, Patent Foramen Ovale
AWARE Registry: Wearable ECG in Structural Heart Interventions
This study is a multi-center (Sinchon Severance hospital / Gangnam Severance hospital), prospective cohort observational study to patients who had undergone structural heart intervention including device closure for secundum type…
- Trial name
- NCT06236776
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
Congenital Heart Diseases
The Role of Multislice Computed Tomography in Congenital Heart Diseases in Paediatric Age Group.
This study aims to evaluate the added value of cardiac multislice Computed Tomography in assessment of CHD in pediatrics as a non-invasive presurgical planning method
- Trial name
- NCT06223321
- Testing
- Computed Tomography in congenital heart diseases
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Congenital Heart Defect
Effect of Educational Program on Parental Stress of Parents of Children With CHD
Congenital Heart disease accounts for about one third of the all congenital anomalies. In last decades' huge advancements occurred in treatment and diagnosis.
- Trial name
- NCT06172608
- Testing
- psychoeducational intervention
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Zhengzhou University
Cardiac Congenital Defects
Volume Versus Pressure Ventilation on Lung Atelectasis
This prospective randomized comparative study, to assess post-operative lung atelectasis by comparing calculated lung score using ultrasound between pediatric patients intubated with LMA (laryngeal mask airway) under volume…
- Trial name
- NCT06076395
- Testing
- LMA (Laryngeal Mask Airway)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Down Syndrome, Congenital Heart Disease
Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)
The study objective is to compare neurodevelopmental (ND) and behavioral outcomes between children with Down syndrome (DS) who had complete atrioventricular septal defect (CAVSD) repair and children from the same clinical sites…
- Trial name
- CHILD-DS (NCT05312177)
- Testing
- Stanford Binet Intelligence Scales, Fifth Edition, Vineland Adaptive Behavior Scales Third Edition, Peabody Picture Vocabulary Test, Fifth Edition
- Where
- 14 sites in United States, Canada
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Infective Endocarditis, Congenital Heart Disease
Infective Endocarditis in Percutaneous Pulmonary Revalvulation: Comparison Between Melody and Sapien Valves
Percutaneous pulmonary valve revalvulation (PPVR) has emerged as an alternative to surgery for the treatment of congenital heart disease with right ejection pathway dysfunction.
- Conditions
- Infective Endocarditis, Congenital Heart Disease, Percutaneous Pulmonary Valve Implantation
- Trial name
- Endopulm (NCT06186258)
- Testing
- percutaneous pulmonary valve implantation (PPVI)
- Where
- 18 sites in France, Germany and 5 more
- Volunteers
- 300 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Pulmonary Arterial Hypertension, Heart Defects, Congenital
The Effects of the Otago Exercise Program
The objective of this experimental study is to conduct a comparative evaluation of the effects of a supervised Otago Exercise Program (OEP) functional exercise capacity, blood lactate levels, dyspnea, fatigue, peripheral muscle…
- Trial name
- NCT06172790
- Testing
- Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Eisenmenger Syndrome
Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger Syndrome
The Eisenmenger syndrome corresponds to the most advanced form of pulmonary arterial hypertension associated with congenital heart disease.
- Trial name
- NCT05611268
- Testing
- Pentoxifylline
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- University of Sao Paulo General Hospital
Congenital Heart Disease in Children
How to Report Postoperative Outcomes After a Paediatric Cardiac Surgery ?
Congenital heart disease is a common abnormality in newborns. The marked improvement in the surgical management of congenital heart disease has led to a reduction in postoperative mortality, historically a quality criterion for…
- Trial name
- Pedia-Card (NCT05546983)
- Where
- France
- Volunteers
- 189 people
- Sponsor
- University Hospital, Strasbourg, France
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Mothers, Quality of Life
The Effect of Web-based Training Given to Mothers of Babies With Congenital Heart Disease
This study was assessed the impact of a web-based education program provided to mothers of infants with congenital heart diseases on their quality of life and self-efficacy levels.
- Conditions
- Mothers, Quality of Life, Self Efficacy, Training
- Trial name
- NCT06168344
- Testing
- Web-Based Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Mother-Infant Interaction
Bonding, Self-effıcacy and Vital Signs in Infants Undergoing Cardiovascular Surgery
Congenital heart diseases, the most common type of congenital anomalies, which affect approximately 3% of all live births and are the second most common cause of death in infants, are associated with 7% of all neonatal deaths.
- Trial name
- NCT06158373
- Testing
- infant massage practice, Safe Swaddling, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Congenital Heart Disease, Fontan Operation
The Role of the Pulmonary Vasculature in the Fontan Circulation
This study aims to explore the structural and functional characteristics of the pulmonary vasculature in adult Fontan patients. Objectives: Determine the effect of pulmonary vasodilatation on indexed cardiac output during…
- Conditions
- Congenital Heart Disease, Fontan Operation, Pulmonary Vascular Resistance, Pulmonary Vascular Remodeling
- Trial name
- NCT02414321
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Congenital Heart Disease, Congenital Heart Defects
Cardiac Rehabilitation in Congenital Heart Disease: Effects on Brain and Cognitive Functions
The proposed trial is designed to evaluate the effect of an individualised cardiac rehabilitation program, consisting of aerobic and muscle strengthening exercises, on brain activity and cognitive functions in adults with…
- Trial name
- CongeNIRS (NCT05195788)
- Testing
- Cardiac rehabilitation
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Montreal Heart Institute
Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection
Central Venous Catheter Insertion Site and Colonization in Pediatric Cardiac Surgery
Randomized controlled trial comparing femoral vs internal jugular insertion site of central venous catheters (CVC) in newborns and infants undergoing cardiac surgery.
- Conditions
- Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection, Heart; Surgery, Heart, Functional Disturbance as Result, Congenital Heart Disease
- Trial name
- PRECiSE (NCT03282292)
- Testing
- Internal jugular vein CVC insertion
- Where
- Italy
- Sponsor
- IRCCS Policlinico S. Donato
Atrial Septal Defect
Improvement In Left Ventricular Diameter After Closure Of ASD With Fenestrated Patch: A Cross-sectional Study
Introduction: The presence of pulmonary hypertension (PH) in atrial septal defect (ASD) poses a clinical challenge on whether or not to close the defect.
- Trial name
- NCT06139679
- Testing
- ASD closure with fenestrated/non-fenestrated patch
- Where
- Indonesia
- Volunteers
- 21 people
- Sponsor
- Dr. Soetomo General Hospital
Transcatheter Neonatal Cardiac Interventions
Neonatal Transcatheter Cardiac Interventions at Sohag University Hospital
This study is performed to assess the safety, efficacy and outcome of transcatheter cardiac interventions in neonates with critical congenital heart disease at Sohag University Hospital
- Trial name
- NCT06126484
- Testing
- transcatheter cardiac intervention
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Congenital Heart Defects
Congenital Heart Defects
Describe the relationship between maternal diabetes and congenital heart defects in infants born to diabetic mothers referred to NICU unit \& Outpatient clinics of Assiut University Childeren's hospital.We will compare between 2…
- Trial name
- NCT06124443
- Volunteers
- 60 people
- Sponsor
- Assiut University
Congenital Heart Disease
Subcostal Transverse Abdominis Plane Block for Epigastric Cardiac Pacemaker Operation
This prospective randomized controlled trial aims to examine the effect of subcostal transverse abdominis plane block on the postoperative pain and opioid consumption in patients (12y≤ age) who will undergo epigastric cardiac…
- Trial name
- NCT04570878
- Testing
- SC TAP, Control
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Hospital